Bio

Clinical Focus


  • Neonatal Hospitalist
  • Neonatology
  • Neonatal Resuscitation

Academic Appointments


Administrative Appointments


  • Associate Director, Packard Intermediate Care Nursery, Division of Neonatology (2005 - Present)
  • Director, Neonatal Hospitalist Program, Division of Neonatology (2005 - Present)

Boards, Advisory Committees, Professional Organizations


  • Co-Chair, AAP SOHM Neonatal Hospitalist Subcommittee (2017 - Present)
  • Member, SOHM Liaison, NRP Steering Committee (2015 - Present)
  • Steering Group/Executive Board Member, AAP SOHM Neonatal Hospitalist subcommittee (2015 - Present)

Professional Education


  • Residency:Stanford University School of Medicine Registrar (2002) CA
  • Internship:Stanford University School of Medicine Registrar (2000) CA
  • Board Certification: Pediatrics, American Board of Pediatrics (2002)
  • Medical Education:Vanderbilt University (1999) TN
  • Residency, Stanford University - LPCH, Pediatrics (2002)
  • M.D., Vanderbilt University, Medicine (1999)
  • B.S., Duke University, Biology, Psychology (1995)

Publications

All Publications


  • Clinical Monitoring of Well-Appearing Infants Born to Mothers With Chorioamnionitis. Pediatrics Joshi, N. S., Gupta, A., Allan, J. M., Cohen, R. S., Aby, J. L., Weldon, B., Kim, J. L., Benitz, W. E., Frymoyer, A. 2018; 141 (4)

    Abstract

    The risk of early-onset sepsis is low in well-appearing late-preterm and term infants even in the setting of chorioamnionitis. The empirical antibiotic strategies for chorioamnionitis-exposed infants that are recommended by national guidelines result in antibiotic exposure for numerous well-appearing, uninfected infants. We aimed to reduce unnecessary antibiotic use in chorioamnionitis-exposed infants through the implementation of a treatment approach that focused on clinical presentation to determine the need for antibiotics.Within a quality-improvement framework, a new treatment approach was implemented in March 2015. Well-appearing late-preterm and term infants who were exposed to chorioamnionitis were clinically monitored for at least 24 hours in a level II nursery; those who remained well appearing received no laboratory testing or antibiotics and were transferred to the level I nursery or discharged from the hospital. Newborns who became symptomatic were further evaluated and/or treated with antibiotics. Antibiotic use, laboratory testing, culture results, and clinical outcomes were collected.Among 277 well-appearing, chorioamnionitis-exposed infants, 32 (11.6%) received antibiotics during the first 15 months of the quality-improvement initiative. No cases of culture result-positive early-onset sepsis occurred. No infant required intubation or inotropic support. Only 48 of 277 (17%) patients had sepsis laboratory testing. The implementation of the new approach was associated with a 55% reduction (95% confidence interval 40%-65%) in antibiotic exposure across all infants ≥34 weeks' gestation born at our hospital.A management approach using clinical presentation to determine the need for antibiotics in chorioamnionitis-exposed infants was successful in reducing antibiotic exposure and was not associated with any clinically relevant delays in care or adverse outcomes.

    View details for DOI 10.1542/peds.2017-2056

    View details for PubMedID 29599112

  • Optimal Criteria Survey for Preresuscitation Delivery Room Checklists. American journal of perinatology Brown, T., Tu, J., Profit, J., Gupta, A., Lee, H. C. 2016; 33 (2): 203-207

    Abstract

    Objective To investigate the optimal format and content of delivery room reminder tools, such as checklists. Study Design Voluntary, anonymous web-based surveys on checklists and reminder tools for neonatal resuscitation were sent to clinicians at participating hospitals. Summary statistics including the mean and standard deviation of the survey items were calculated. Several key comparisons between groups were completed using Student t-test. Results Fifteen hospitals were surveyed and 299 responses were collected. Almost all (96%) respondents favored some form of a reminder tool. Specific reminders such as "check and prepare all equipment" (mean 3.69, SD 0.81) were ranked higher than general reminders and personnel reminders such as "introduction and assigning roles" (mean 3.23, SD 1.08). Rankings varied by profession, institution, and deliveries attended per month. Conclusions Clinicians perceive a benefit of a checklist for neonatal resuscitation in the delivery room. Preparation of equipment was perceived as the most important use for checklists.

    View details for DOI 10.1055/s-0035-1564064

    View details for PubMedID 26368913