Andrew Gentles

Assistant Professor (Research) of Pathology, of Medicine (BMIR) and, by courtesy, of Biomedical Data Science

Bio

BSc (Hons) Physics, University of Manchester, UK
PhD Theoretical particle physics, University of Southampton, UK

Academic Appointments

Assistant Professor (Research), Pathology
Assistant Professor (Research), Medicine - Biomedical Informatics Research
Assistant Professor (Research) (By courtesy), Biomedical Data Science
Member, Bio-X
Member, Cardiovascular Institute
Member, Stanford Cancer Institute
Member, Wu Tsai Neurosciences Institute

Current Research and Scholarly Interests

Computational systems biology

Stanford Advisees

Doctoral Dissertation Reader (AC)
Vandon Duong, Noah Greenwald, Warren Reynolds
Postdoctoral Faculty Sponsor
Ruohan Wang
Doctoral Dissertation Co-Advisor (AC)
Emma Heaton, Ilayda Ilerten

Graduate and Fellowship Programs

Biomedical Informatics (Masters Program)
Biomedical Informatics (Phd Program)
Cancer Biology (Phd Program)
Immunology (Phd Program)

All Publications

Profiles With Related Publications

close
Ash A. Alizadeh, MD/PhD

Moghadam Family Professor
Clinical Focus
Cancer > Lymphoma, Lymphoma, B-Cell Chronic Lymphocytic Leukemia, Waldenstrom Macroglobulinemia, Burkitt Lymphoma, Follicular Lymphoma, Diffuse Large-Cell Lymphomas, Leukemia, Hairy Cell, Lymphoma, B-Cell, Marginal Zone, Hodgkin Disease, Medical Oncology
Research Interests
My research is focused on attaining a better understanding of the initiation, maintenance, and progression of tumors, and their response to current therapies toward improving future treatment strategies. In this effort, I employ tools from functional genomics, computational biology, molecular genetics, and mouse models.

Clinically, I specialize in the care of patients with lymphomas, working on translating our findings in prospective cancer clinical trials.

410 Total Publications
close
Swaroop Aradhya

Adjunct Clinical Professor, Pathology
Clinical Focus
Clinical Pathology, Clinical laboratory genomics, Neurodevelopmental genetic disorders

130 Total Publications
close
Gill Bejerano

Professor of Developmental Biology, of Computer Science, of Pediatrics (Genetics) and of Biomedical Data Science
Research Interests
1. Automating monogenic patient diagnosis.
2. The genomic signatures of independent divergent and convergent trait evolution in mammals.
3. The logic of human gene regulation.
4. The reasons for sequence ultraconservation.
5. Cryptogenomics to bridge medical silos.
6. Cryptogenetics to debate social injustice.
7. Managing patient risk using machine learning.
8. Understanding the flow of money in the US healthcare system.

132 Total Publications
close
Patrick O. Brown

Professor of Biochemistry, Emeritus
Research Interests
Dr. Brown's research focuses on replacing humanity's most destructive invention - the use of animals as a food technology - by developing a new and better way to produce the world's most delicious, nutritious and affordable meats, fish and dairy foods directly from plants. He is also working on developing and scaling optimal methods for restoring healthy ecosystems and sequestering carbon on the 45% of Earth's surface that have been devastated by animal agriculture.

319 Total Publications
close
Howard Y. Chang, MD, PhD

Virginia and D. K. Ludwig Professor of Cancer Research, Professor of Genetics and, by courtesy, of Pathology
Clinical Focus
Cancer > Cutaneous (Dermatologic) Oncology, Dermatology, General Dermatology
Research Interests
Our research is focused on how the activities of hundreds or even thousands of genes (gene parties) are coordinated to achieve biological meaning. We have pioneered methods to predict, dissect, and control large-scale gene regulatory programs; these methods have provided insights into human development, cancer, and aging.

489 Total Publications
close
Mike Cherry

Professor (Research) of Genetics, Emeritus
Research Interests
My research involves identifying, validating and integrating scientific facts into encyclopedic databases essential for research and scientific education. Published results of scientific experimentation are a foundation of our understanding of the natural world and provide motivation for new experiments. The combination of in-depth understanding reported in the literature with computational analyses is an essential ingredient of modern biological research.

145 Total Publications
close
Maximilian Diehn, MD, PhD

Jack, Lulu, and Sam Willson Professor and Professor of Radiation Oncology (Radiation Therapy)
Clinical Focus
Cancer > Radiation Oncology, Cancer > Thoracic Oncology, Radiation Oncology, Radiation Therapy
Research Interests
My laboratory focuses on two main areas: 1) cancer stem cell biology and 2) novel biomarkers for identifying the presence of malignant cells (diagnostic), predicting outcome (prognostic), and predicting response to therapy (predictive). Areas of study include cancers of the lung, breast, and gastrointestinal system. Clinically I specialize in the treatment of lung cancer and applications of stereotactic ablative radiotherapy and perform both prospective and retrospective clinical studies.

470 Total Publications
close
Dean W. Felsher

Professor of Medicine (Oncology) and of Pathology
Research Interests
My laboratory studies the molecular basis of cancer with a focus on understanding when cancer can be reversed through targeted oncogene inactivation.

217 Total Publications
close
Olivier Gevaert

Associate Professor of Medicine (Biomedical Informatics) and of Biomedical Data Science
Research Interests
My lab focuses on biomedical data fusion: the development of machine learning methods for biomedical decision support using multi-scale biomedical data. We primarily use methods based on regularized linear regression to accomplish this. We primarily focus on applications in oncology and neuroscience.

199 Total Publications
close
Hanlee P. Ji

Professor of Medicine (Oncology) and, by courtesy of Electrical Engineering
Clinical Focus
Cancer > GI Oncology, Medical Oncology, Oncology (Cancer), Gastrointestinal Neoplasms, Inherited Cancer Disorders, Immunotherapy in gastrointestinal cancers
Research Interests
Cancer genomics and genetics, translational applications of next generation sequencing technologies, development of molecular signatures as prognostic and predictive biomarkers in oncology, primary genomic and proteomic technology development, cancer rearrangements, genome sequencing, big data analysis

200 Total Publications
close
Ronald Levy, MD

Robert K. and Helen K. Summy Professor in the School of Medicine
Clinical Focus
Cancer > Lymphoma, Lymphoma , Non-Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma - Medical Oncology, Burkitt's Lymphoma, Burkitt's Lymphoma - Medical Oncology, Hodgkin's Disease, Hodgkin's Disease - Medical Oncology, Burkitt's Lymphoma - Hematology, Hodgkin's Disease - Hematology, Oncology (Cancer), Non-Hodgkin's Lymphoma - Hematology, Medical Oncology
Research Interests
Clinical Interests: lymphoma. Research Interests: Immunology and molecular biology of lymphoid malignancy; molecular vaccines for cancer.

422 Total Publications
close
Ravi Majeti MD, PhD

Director, Stanford Institute for Stem Cell Biology and Regenerative Medicine, Virginia and D. K. Ludwig Professor and Professor of Medicine (Hematology)
Research Interests
The Majeti lab focuses on the molecular/genomic characterization and therapeutic targeting of leukemia stem cells in human hematologic malignancies, particularly acute myeloid leukemia (AML). Our lab uses experimental hematology methods, stem cell assays, genome editing, and bioinformatics to define and investigate drivers of leukemia stem cell behavior. As part of these studies, we have led the development and application of robust xenotransplantation assays for human hematopoietic cells.

190 Total Publications