Andrew Gentles

Associate Professor (Research) of Pathology, of Medicine (BMIR) and, by courtesy, of Biomedical Data Science

Bio

BSc (Hons) Physics, University of Manchester, UK
PhD Theoretical particle physics, University of Southampton, UK

Academic Appointments

Associate Professor (Research), Pathology
Associate Professor (Research), Medicine - Biomedical Informatics Research
Associate Professor (Research) (By courtesy), Department of Biomedical Data Science
Member, Bio-X
Member, Cardiovascular Institute
Member, Stanford Cancer Institute
Member, Wu Tsai Neurosciences Institute

Current Research and Scholarly Interests

Computational systems biology

Stanford Advisees

Doctoral Dissertation Reader (AC)
Diego Almanza, Vandon Duong, Rachel Gleyzer, Kevin Liu, Warren Reynolds
Postdoctoral Faculty Sponsor
Brendan Ball, Ruohan Wang
Master's Program Advisor
Karen Flores Cano
Doctoral Dissertation Co-Advisor (AC)
Emma Heaton, Ilayda Ilerten

Graduate and Fellowship Programs

Biomedical Data Science (Masters Program)
Biomedical Data Science (Phd Program)
Cancer Biology (Phd Program)
Immunology (Phd Program)

All Publications

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Ash A. Alizadeh, MD/PhD

Moghadam Family Professor
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Cancer > Lymphoma, Lymphoma, B-Cell Chronic Lymphocytic Leukemia, Waldenstrom Macroglobulinemia, Burkitt Lymphoma, Follicular Lymphoma, Diffuse Large-Cell Lymphomas, Leukemia, Hairy Cell, Lymphoma, B-Cell, Marginal Zone, Hodgkin Disease, Medical Oncology
Research Interests
My research is focused on attaining a better understanding of the initiation, maintenance, and progression of tumors, and their response to current therapies toward improving future treatment strategies. In this effort, I employ tools from functional genomics, computational biology, molecular genetics, and mouse models.

Clinically, I specialize in the care of patients with lymphomas, working on translating our findings in prospective cancer clinical trials.

430 Total Publications
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Gill Bejerano

Professor of Developmental Biology, of Computer Science, of Pediatrics (Genetics) and of Biomedical Data Science
Research Interests
1. Automating monogenic patient diagnosis.
2. The genomic signatures of independent divergent and convergent trait evolution in mammals.
3. The logic of human gene regulation.
4. The reasons for sequence ultraconservation.
5. Cryptogenomics to bridge medical silos.
6. Cryptogenetics to debate social injustice.
7. Managing patient risk using machine learning.
8. Understanding the flow of money in the US healthcare system.

133 Total Publications
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Patrick O. Brown

Professor of Biochemistry, Emeritus
Research Interests
Dr. Brown's research focuses on replacing humanity's most destructive invention - the use of animals as a food technology - by developing a new and better way to produce the world's most delicious, nutritious and affordable meats, fish and dairy foods directly from plants. He is also working on developing and scaling optimal methods for restoring healthy ecosystems and sequestering carbon on the 45% of Earth's surface that have been devastated by animal agriculture.

319 Total Publications
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Mike Cherry

Professor (Research) of Genetics, Emeritus
Research Interests
My research involves identifying, validating and integrating scientific facts into encyclopedic databases essential for research and scientific education. Published results of scientific experimentation are a foundation of our understanding of the natural world and provide motivation for new experiments. The combination of in-depth understanding reported in the literature with computational analyses is an essential ingredient of modern biological research.

149 Total Publications
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Jesse Engreitz

Assistant Professor of Genetics
Research Interests
Regulatory elements in the human genome harbor thousands of genetic risk variants for common diseases and could reveal targets for therapeutics — if only we could map the complex regulatory wiring that connects 2 million regulatory elements with 21,000 genes in thousands of cell types in the human body.

We combine experimental and computational genomics, biochemistry, molecular biology, and genetics to assemble regulatory maps of the human genome and uncover biological mechanisms of disease.

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Dean W. Felsher

Professor of Medicine (Oncology) and of Pathology
Research Interests
My laboratory studies the molecular basis of cancer with a focus on understanding when cancer can be reversed through targeted oncogene inactivation.

224 Total Publications
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Olivier Gevaert

Associate Professor of Medicine (Biomedical Informatics) and of Biomedical Data Science
Research Interests
My lab focuses on biomedical data fusion: the development of machine learning methods for biomedical decision support using multi-scale biomedical data. We primarily use methods based on regularized linear regression to accomplish this. We primarily focus on applications in oncology and neuroscience.

214 Total Publications
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Hanlee P. Ji

Professor of Medicine (Oncology) and, by courtesy of Electrical Engineering
Clinical Focus
Cancer > GI Oncology, Medical Oncology, Oncology (Cancer), Gastrointestinal Neoplasms, Inherited Cancer Disorders, Immunotherapy in gastrointestinal cancers
Research Interests
Cancer genomics and genetics, translational applications of next generation sequencing technologies, development of molecular signatures as prognostic and predictive biomarkers in oncology, primary genomic and proteomic technology development, cancer rearrangements, genome sequencing, big data analysis

209 Total Publications
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Ronald Levy, MD

Robert K. and Helen K. Summy Professor in the School of Medicine
Clinical Focus
Cancer > Lymphoma, Lymphoma , Non-Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma - Medical Oncology, Burkitt's Lymphoma, Burkitt's Lymphoma - Medical Oncology, Hodgkin's Disease, Hodgkin's Disease - Medical Oncology, Burkitt's Lymphoma - Hematology, Hodgkin's Disease - Hematology, Oncology (Cancer), Non-Hodgkin's Lymphoma - Hematology, Medical Oncology
Research Interests
Clinical Interests: lymphoma. Research Interests: Immunology and molecular biology of lymphoid malignancy; molecular vaccines for cancer.

425 Total Publications
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Gordon Li, MD

Professor of Neurosurgery and, by courtesy, of Neurology and Neurological Sciences and of Otolaryngology - Head & Neck Surgery (OHNS)
Clinical Focus
Cancer > Neuro Oncology, Neurosurgery, Brain Tumors, radiosurgery, Minimally Invasive Surgical Procedures
Research Interests
1.) My laboratory studies the biology of brain tumors with the goal of developing novel therapeutics for the treatment of malignant brain tumors and translating that research into clinical trials.
2.) My clinical interests include improving surgical techniques for brain tumor surgery, immunotherapy for the treatment of glioblastoma, and novel uses for stereotactic radiosurgery.

219 Total Publications
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Emma Lundberg

Associate Professor of Bioengineering and of Pathology

137 Total Publications
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Ravi Majeti MD, PhD

Director, Stanford Institute for Stem Cell Biology and Regenerative Medicine, Virginia and D. K. Ludwig Professor and Professor of Medicine (Hematology/Stem Cell Institute)
Research Interests
The Majeti lab focuses on the molecular/genomic characterization and therapeutic targeting of leukemia stem cells in human hematologic malignancies, particularly acute myeloid leukemia (AML). Our lab uses experimental hematology methods, stem cell assays, genome editing, and bioinformatics to define and investigate drivers of leukemia stem cell behavior. As part of these studies, we have led the development and application of robust xenotransplantation assays for human hematopoietic cells.

194 Total Publications