Support teaching, research, and patient care.
We develop quantitative imaging methods to characterize the tumor microenvironment, and to subsequently relate these imaging parameters to biomarkers that can be used for cancer surveillance, diagnosis and treatment monitoring/characterization. The focus is on 1) developing new acquisition methods and protocols to enhance quantification, 2) designing new image processing algorithms, analysis parameters and statistical models to quantitatively characterize imaging data, and 3) using advanced AI methods to further refine quantification or classification. While our methods can be used for other imaging modalities, we primarily focus on Ultrasound imaging modes such as contrast, molecular, elastography and spectroscopic ultrasound. Disease focus include liver cancer and liver metastasis, liver fibrosis/cirrhosis, and tumor blood flow characterization.