Aerin Yang

Basic Life Research Scientist, Molecular and Cellular Physiology

All Publications

Publications (15)

All Publications (15)
Featured Publications (4)
Journal Articles (15)

Profiles With Related Publications

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Anne Brunet

Michele and Timothy Barakett Endowed Professor
Research Interests
Our lab studies the molecular basis of longevity. We are interested in the mechanism of action of known longevity genes, including FOXO and SIRT, in the mammalian nervous system. We are particularly interested in the role of these longevity genes in neural stem cells. We are also discovering novel genes and processes involved in aging using two short-lived model systems, the invertebrate C. elegans and an extremely short-lived vertebrate, the African killifish N. furzeri.

155 Total Publications
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Dennis J Bua

Administrative Co-Director, School of Medicine - IDP's - MSTP

8 Total Publications
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Katrin Chua

Professor of Medicine (Endocrinology, Gerontology and Metabolism)

51 Total Publications
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Karlene Cimprich

Professor of Chemical and Systems Biology and, by courtesy, of Biochemistry
Research Interests
Genomic instability contributes to many diseases, but it also underlies many natural processes. The Cimprich lab is focused on understanding how mammalian cells maintain genomic stability in the context of DNA replication stress and DNA damage. We are interested in the molecular mechanisms underlying the cellular response to replication stress and DNA damage as well as the links between DNA damage and replication stress to human disease.

75 Total Publications
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Gerald Crabtree

David Korn, MD, Professor of Pathology and Professor of Developmental Biology
Research Interests
Chromatin regulation and its roles in human cancer and the development of the nervous system. Engineering new methods for studying and controlling chromatin and epigenetic regulation in living cells.

265 Total Publications
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James Ferrell

Professor of Chemical and Systems Biology and of Biochemistry
Research Interests
My lab has two main goals: to understand the regulation of mitosis and to understand the systems-level logic of simple signaling circuits. We often make use of Xenopus laevis oocytes, eggs, and cell-free extracts for both sorts of study. We also carry out single-cell fluorescence imaging studies on mammalian cell lines. Our experimental work is complemented by computational and theoretical studies aimed at understanding the design principles and recurring themes of regulatory circuits.

152 Total Publications
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Or Gozani

Dr. Morris Herzstein Professor
Research Interests
We study the molecular mechanisms by which chromatin-signaling networks effect nuclear and epigenetic programs, and how dysregulation of these pathways leads to disease. Our work centers on the biology of lysine methylation, a principal chromatin-regulatory mechanism that directs epigenetic processes. We study how lysine methylation events are generated, sensed, and transduced, and how these chemical marks integrate with other nuclear signaling systems to govern diverse cellular functions.

122 Total Publications
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Li Guan

Basic Life Research Scientist, Radiation Oncology - Radiation Therapy

11 Total Publications
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Peter K. Jackson

Professor of Microbiology and Immunology (Baxter Labs) and of Pathology
Research Interests
Cell cycle and cyclin control of DNA replication .

180 Total Publications
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Justyna Janas

Basic Life Research Scientist, Stem Cell Bio Regenerative Med Institute

14 Total Publications
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Ron Kopito

Professor of Biology
Research Interests
Our laboratory use state-of-the-art cell biological, genetic and systems-level approaches to understand how proteins are correctly synthesized, folded and assembled in the mammalian secretory pathway, how errors in this process are detected and how abnormal proteins are destroyed by the ubiquitin-proteasome system.

129 Total Publications
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Michael Lin

Associate Professor of Neurobiology, of Bioengineering and, by courtesy, of Chemical and Systems Biology
Research Interests
Our lab applies biochemical and engineering principles to the development of protein-based tools for investigating biology in living animals. Topics of investigation include fluorescent protein-based voltage indicators, synthetic light-controllable proteins, bioluminescent reporters, and applications to studying animal models of disease.

87 Total Publications