Melanie Hayden Gephart

Professor of Neurosurgery and, by courtesy, of Neurology

Bio

I am a brain tumor neurosurgeon, treating patients with primary and metastatic brain tumors. I treat patients with malignant and benign tumors, including glioma, brain metastases, meningioma, and vestibular schwannomas. I direct the Stanford Brain Tumor Center and the Stanford Brain Metastasis Consortium, collaborative unions of physicians and scientists looking to improve our understanding and treatment of brain tumors. My laboratory seeks greater understanding of the mechanisms driving tumorigenesis and disease progression in malignant brain tumors. We study how rare cancer cell populations survive and migrate in the brain, inadvertently supported by native brain cells. We develop novel cell free nucleic acid biomarkers to track brain cancer treatment response, relapse, and neurotoxicity. Our bedside-to-bench-to-bedside research model builds on a foundation of generously donated patient samples, where we test mechanisms of brain cancer growth, develop novel pre-clinical models that reliably recapitulate the human disease, and facilitate clinical trials of new treatments for patients with brain cancer.

www.GephartLab.com
www.GBMseq.org
https://stan.md/BrainMets
@HaydenGephartMD

Clinical Focus

Neurosurgery

Academic Appointments

Professor - University Medical Line, Neurosurgery
Professor - University Medical Line (By courtesy), Neurology & Neurological Sciences
Member, Bio-X
Member, Maternal & Child Health Research Institute (MCHRI)
Member, Stanford Cancer Institute

Administrative Appointments

Associate Program Director, Neurosurgery Residency (2022 - Present)
Co-Director, Stanford Brain Tumor Center, Stanford University (2018 - Present)
Director, Stanford Brain Metastases Consortium (2018 - Present)

Professional Education

Neurosurgery Residency, Stanford University (2014)
MD, University of California at San Diego (2007)
Board Certification: American Board of Neurological Surgery, Neurosurgery (2018)
Masters of Advanced Sciences, University of California at San Diego, Clinical Research (2007)
BS, University of California at San Diego, Neuroscience and Physiology (2001)

Contact

Academic mghayden@stanford.edu

Stanford Brain Tumor Center Tel: 650 497 7777

Clinical Stanford Cancer Center 875 Blake Wilbur Dr Clinic A MC 6560 Stanford CA 94305 Tel: (650) 498-6000 Fax: (650) 724-3556
Clinical Stanford Neuroscience Health Center 213 Quarry Rd 4th Fl MC 5958 Palo Alto CA 94304 Tel: (650) 723-6469 Fax: (650) 725-0390

2022-23 Courses

Independent Studies
- Directed Reading in Neurosurgery
  NSUR 299 (Aut, Win, Spr)
- Early Clinical Experience in Neurosurgery
  NSUR 280 (Aut, Win, Spr)
- Graduate Research
  NSUR 399 (Aut, Win, Spr)
- Medical Scholars Research
  NSUR 370 (Aut, Win, Spr, Sum)
- Undergraduate Research
  NSUR 199 (Aut, Win, Spr)

Stanford Advisees

Med Scholar Project Advisor
Guan Li, Adrian Rodrigues
Postdoctoral Faculty Sponsor
Giuseppe Barisano, Shruti Jain, Zheng Hao Samuel Wong

All Publications

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See Biosketch for details.

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