Support teaching, research, and patient care.
Dr. Jack Wang is a physician-scientist and a neurointensivist at Stanford University Medical Center, where he currently cares for critically ill patients with neurological illnesses in the ICU. He has particular clinical and research interests in stroke and traumatic brain injury, and currently leads an active translational effort to identify novel therapeutic targets to promote functional recovery after brain and spinal cord injuries.
Our primary research focus is understanding the molecular mechanisms of axonal degeneration and subsequent failure of axonal regeneration in the CNS. We have identified critical cellular pathways mediating axonal degeneration following acute neurological injuries including ischemic stroke and traumatic brain injury. Modulating these pathways presents a novel therapeutic strategy to protect vulnerable nerve fibers and enhance functional recovery in a multitude of acute CNS injuries and diseases.