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Dr. Jack Wang is a physician-scientist and a neurointensivist at Stanford University Medical Center, where he currently cares for critically ill patients with neurological illnesses in the ICU. He has particular clinical and research interests in stroke and traumatic brain injury, and currently leads an active translational effort to identify novel therapeutic targets to promote functional recovery after brain and spinal cord injuries.
My primary research focus is in understanding the molecular mechanisms of axonal degeneration and subsequent failure of axonal regeneration in the CNS. I have identified a critical cellular pathway mediating axonal degeneration following neurological injuries. Modulating this pathway presents a novel therapeutic target to protect vulnerable nerve fibers and enhance functional recovery in a multitude of CNS diseases.