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We are interested in the basic principles that govern interactions within the intestinal microbiota and between the microbiota and the host. To pursue these aims, we colonize germ-free (gnotobiotic) mice with simplified, model microbial communities, apply systems approaches (e.g. functional genomics), and use genetic tools for the host and microbes to gain mechanistic insight into emergent properties of the host-microbial super-organism.
Contrasting Ketogenic and Mediterranean Diets in Individuals With Type 2 Diabetes and Prediabetes: The Keto-Med Trial
The objective of this study is to compare two metabolically distinct diets, WFKD vs Med-Plus,
in order to examine the potential benefits, and unintended consequences, of going beyond a
focus on maximally avoiding added sugars and refined grains, to also avoiding legumes,
fruits, and whole grains.
Stanford is currently not accepting patients for this trial.
For more information, please contact Jennifer Robinson, PhD, 650-736-8577.
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The RAMP Study - Rejuvenation of the Aging Microbiota With Prebiotics
An individual's immune and metabolic status is coupled to consumed carbohydrates. Complex
carbohydrates that are not digested by human enzymes may influence host biology by impacting
microbiota composition and function, or act in a yet-unknown microbiota-independent manner.
Prebiotics offer a promising safe route to influence host health, possibly via the
microbiota. However, it remains largely unknown to what extent immune function and metabolism
can be modulated by prebiotics.