Current Research and Scholarly Interests
Dr. Witteles' research focuses on three major areas:
1) Amyloidosis -- As Co-Director of the Stanford Amyloid Center, Dr. Witteles works with a team of investigators to explore novel therapies for amyloidosis and to better understand the mechanisms underlying the disease. This work ranges from clinical trials for multiple types of amyloidosis (AL, ATTR), to defining the role of organ transplantation and pacemakers/defibrillators, to partnering with basic science labs to explore basic principles of pathogenesis.
2) CardioOncology (Cardiac toxicity of cancer therapies) -- Studying optimal prevention and treatment strategies for patients who develop heart failure and other cardiac toxicity as a consequence of cancer therapies, as well as studies to better understand the mechanisms/patterns of toxicity for multiple chemotherapeutic agents. Dr. Witteles serves as Associate Editor for JACC: CardioOncology, the world's leading journal devoted to the field.
3) Sarcoidosis -- As Co-Director of the Stanford Multidisciplinary Sarcoidosis Program, Dr. Witteles studies novel diagnostic modalities to improve the accuracy of disease diagnosis and the ability to follow responses to treatment of the disease, partners with laboratories to understand the pathogenesis of the disease, and studies new treatments for the disease.