Bio

Professional Education


  • Bachelor of Science, University of Washington (2008)
  • Doctor of Philosophy, University of California Davis (2014)

Stanford Advisors


Research & Scholarship

Lab Affiliations


Publications

All Publications


  • Programmable Microfluidic Synthesis of Over One Thousand Uniquely Identifiable Spectral Codes Advanced Optical Materials Nguyen, H. Q., Baxter, B. C., Brower, K., Diaz-Botia, C. A., DeRisi, J. L., Fordyce, P. M., Thorn, K. S. 2016: 6

    View details for DOI 10.1002/adom.201600548

  • Synthesis and Structural Characterization of Three Unique Helicobacter pylori alpha-Cholesteryl Phosphatidyl Glucosides ANGEWANDTE CHEMIE-INTERNATIONAL EDITION Nguyen, H. Q., Davis, R. A., Gervay-Hague, J. 2014; 53 (49): 13400-13403

    Abstract

    Steryl glycosides produced by bacteria play important biological roles in the evasion and modulation of host immunity. Step-economical syntheses of three cholesteryl-6-O-phosphatidyl-α-D-glucopyranosides (αCPG) unique to Helicobacter pylori have been achieved. The approach relies upon regioselective deprotection of per-O-trimethylsilyl-α-D-cholesterylglucoside at C6 followed by phosphoramidite coupling. Global TMS ether deprotection in the presence of oxygen and subsequent deprotection of the cyano ethyl phosphoester afforded the target compounds in 16-21 % overall yield starting from D-glucose. The structures of these natural products were determined using a combination of 2D NMR methods and mass spectrometry. These robust synthesis and characterization protocols provide analogues to facilitate glycolipidomic profiling and biological studies.

    View details for DOI 10.1002/anie.201406529

    View details for Web of Science ID 000345590300012

    View details for PubMedID 25195783