Current Research and Scholarly Interests
We investigate the biological and clinical characteristics that drive resilience in humans using surgery as an interventional injury model. The capacity to recover from injury, or alternatively, suffer from dire consequences, is at the very core of human health. The modern armamentarium in the natural, clinical, and computational sciences allows for an unprecedented exploration of the question as to what constitutes human fitness. Our efforts employ sophisticated multi-omic and computational approaches. Gained knowledge will permit individual patient consultation and management in the field of anesthesiology and perioperative care. Some patients may benefit most from complex and invasive surgical procedures, while others may be better served by minimally invasive or none-surgical interventions. Furthermore, novel strategies are on the horizon to render vulnerable patients fit for surgery with pre-surgical and perioperative interventions.
