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Dr. Fredric Kraemer is a Professor in the Division of Endocrinology, Gerontology and Metabolism. He is a board certified endocrinologist for over 40 years who specializes in the treatment diabetes mellitus, particularly type 1 diabetes, and the treatment of lipid disorders, such as elevated cholesterol or triglycerides.
Our research interests are in the general area of cellular lipid and lipoprotein metabolism. The work is aimed primarily at understanding the mechanisms regulating cholesterol and triglyceride accumulation in cells. We utilize a variety of techniques from cell biology, biochemistry, and molecular biology. Current research projects focus on the regulation of hormone sensitive lipase (HSL). HSL is an intracellular enzyme responsible for the cytosolic hydrolysis of intracellular triglyceride and cholesteryl esters. Thus, it has an important role in fat mobilization, but also in cholesterol metabolism. We are examining all aspects of the biology of HSL, including its mechanisms of action and its structure-function relationships in regard to adipose cell function and steroid hormone synthesis.
Treatment of Psychotic Major Depression With Mifepristone
The purpose of this research study is to see how certain hormones cause changes in mood and
thinking in some depressed patients and to determine the effectiveness of mifepristone in
treating some forms of depression.
This study is conducted in conjunction with an observational study "Clinical and Biological
Characteristics of Psychotic Depression".
Stanford is currently not accepting patients for this trial.
For more information, please contact Lakshika Tennakoon, 6507233305.
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