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Postdoctoral Scholar, Pulmonary and Critical Care Medicine
Books and Book Chapters
Profiles With Related Publications
Cristina Maria Alvira
Associate Professor of Pediatrics (Critical Care)
Intensive Care, Pediatric, Pediatric Critical Care Medicine
The overall objective of the Alvira Laboratory is to elucidate the mechanisms that promote postnatal lung development and repair, by focusing on three main scientific goals: (i) identification of the signaling pathways that direct the transition between the saccular and alveolar stages of lung development; (ii) exploration of the interplay between postnatal vascular and alveolar development; and (iii) determination of developmentally regulated pathways that mediate lung repair after injury.
Professor of Developmental Biology, of Computer Science, of Pediatrics (Genetics) and of Biomedical Data Science
1. Automating monogenic patient diagnosis.
2. The genomic signatures of independent divergent and convergent trait evolution in mammals.
3. The logic of human gene regulation.
4. The reasons for sequence ultraconservation.
5. Cryptogenomics to bridge medical silos.
6. Cryptogenetics to debate social injustice.
7. Managing patient risk using machine learning.
8. Understanding the flow of money in the US healthcare system.
Patrick O. Brown
Professor of Biochemistry, Emeritus
Dr. Brown, currently an emeritus professor, is CEO and founder of Impossible Foods, a company dedicated to replacing the world's most destructive technology - the use of animals to transform plant biomass into meat, fish and dairy foods - by developing a new and better way to produce the world's most delicious, nutritious and affordable meats, fish and dairy foods directly from plants. Visit impossiblefoods.com for more information.
Alan G. Cheng, MD
Edward C. and Amy H. Sewall Professor in the School of Medicine, Professor of Otolaryngology - Head & Neck Surgery (OHNS) and, by courtesy, of Pediatrics
Otolaryngology, Hearing loss, Cholesteotoma, Pediatric sinus disease, Pediatric head and neck tumors
Active Wnt signaling maintains somatic stem cells in many organ systems. Using Wnt target genes as markers, we have characterized distinct cell populations with stem cell behavior in the inner ear, an organ thought to be terminally differentiated. Ongoing work focuses on delineating the developing significance of these putative stem/progenitor cells and their behavior after damage.
Paul Cheng MD PhD
Assistant Professor of Medicine (Cardiovascular Medicine)
Amyloidosis, Cardio-Oncology, Cardiovascular Disease
Maria Inmaculada Cobos Sillero
Assistant Professor of Pathology
Anatomic Pathology, Neuropathology
Professor of Medicine (Pulmonary, Allergy and Critical Care Medicine)
Pulmonary Disease, Interstitial Lung Diseases
Basic and translational research in lung stem cell biology, cancer, pulmonary fibrosis, COPD, and acute lung injury/ARDS. Upper airway stem cell CRISPR gene correction followed by autologous stem cell transplantation to treat Cystic fibrosis. Using lung organoids and precision cut lung slice cultures of mouse and human lungs to study molecular regulation of lung stem cells. Using transgenic mice to visualize Wnt protein transmission from niche cell to stem cell in vivo.
Assistant Professor of Genetics
Regulatory elements in the human genome harbor thousands of genetic risk variants for common diseases and could reveal targets for therapeutics — if only we could map the complex regulatory wiring that connects 2 million regulatory elements with 21,000 genes in thousands of cell types in the human body.
We combine experimental and computational genomics, biochemistry, molecular biology, and genetics to assemble regulatory maps of the human genome and uncover biological mechanisms of disease.
Professor of Surgery (Plastic & Reconstructive Surgery)
Dr. Helms' research interests center around regenerative medicine and craniofacial development.
Associate Professor (Research) of Neurology
We study the role of oxygen free radicals in oxidative tissue damage and degeneration. Our research tools include transgenic and knockout mice and tissue culture cells for in vitro gene expression.
Nicholas Hedemann Juul
Instructor, Medicine - Pulmonary, Allergy & Critical Care Medicine
Paul and Mildred Berg Professor
- Lung development and stem cells
- Neural circuits of breathing and speaking
- Lung diseases including lung cancer
- New genetic model organism for biology, behavior, health and conservation
Publication Topics For This Person
Core Binding Factor Alpha 1 Subunit
Fibroblast Growth Factor 10
Fibroblast Growth Factor 2
Fibroblast Growth Factor 7
Fibroblast Growth Factors
Gene Expression Profiling
Gene Expression Regulation
Gene Expression Regulation, Developmental
Genetic Association Studies
Genetic Diseases, Inborn
Interferon Regulatory Factor-3
Mice, Inbred C3H