Elizabeth Anne Allen

Senior Research Scientist-Basic Life, Obstetrics & Gynecology - Oncology

All Publications

Publications (22)

All Publications (22)
Journal Articles (20)
Conference Proceedings (2)

Profiles With Related Publications

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Helen M. Blau

Donald E. and Delia B. Baxter Foundation Professor, Director, Baxter Laboratory for Stem Cell Biology and Professor, by courtesy, of Psychiatry and Behavioral Sciences
Research Interests
Prof. Helen Blau's research area is regenerative medicine with a focus on stem cells. Her research on nuclear reprogramming and demonstrating the plasticity of cell fate using cell fusion is well known and her laboratory has also pioneered the design of biomaterials to mimic the in vivo microenvironment and direct stem cell fate. Current findings are leading to more efficient iPS generation, cell based therapies by dedifferentiation a la newts, and discovery of novel molecules and therapies.

316 Total Publications
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Michele Calos

Professor of Genetics, Emerita
Research Interests
My lab is developing innovative gene and stem cell therapies for genetic diseases, with a focus on gene therapy and regenerative medicine.

We have created novel methods for inserting therapeutic genes into the chromosomes at specific places by using homologous recombination and recombinase enzymes.

We are working on 3 forms of muscular dystrophy.

We created induced pluripotent stem cells from patient fibroblasts, added therapeutic genes, differentiated, and engrafted the cells.

134 Total Publications
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Ian Y Chen, MD, PhD

Assistant Professor of Medicine (Cardiovascular) and of Radiology (Veterans Affairs)

76 Total Publications
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Steven Chu

William R. Kenan Jr. Professor, Professor of Molecular and Cellular Physiology and of Energy Science and Engineering
Research Interests
Synthesis, functionalization and applications of nanoparticle bioprobes for molecular cellular in vivo imaging in biology and biomedicine. Linear and nonlinear difference frequency mixing ultrasound imaging. Lithium metal-sulfur batteries, new approaches to electrochemical splitting of water. CO2 reduction, lithium extraction from salt water

232 Total Publications
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Christopher H. Contag

Professor of Pediatrics (Neonatology), Emeritus
Research Interests
We develop and use the tools of molecular imaging to understand oncogenesis, reveal patterns of cell migration in immunosurveillance, monitor gene expression, visualize stem cell biology, and assess the distribution of pathogens in living animal models of human biology and disease. Biology doesn't occur in "a vacuum" or on coated plates--it occurs in the living body and that's were we look for biological patterns and responses to insult.

384 Total Publications
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Bianxiao Cui

Job and Gertrud Tamaki Professor of Chemistry
Research Interests
Our objective is to develop new biophysical methods to advance current understandings of cellular machinery in the complicated environment of living cells. Currently, we are focusing on four research areas: (1) Membrane curvature at the nano-bio interface; (2) Nanoelectrode arrays (NEAs) for scalable intracellular electrophysiology; (3) Electrochromic optical recording (ECORE) for neuroscience; and (4) Optical control of neurotrophin receptor tyrosine kinases.

158 Total Publications
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Uta Francke

Professor of Genetics and of Pediatrics, Emerita
Clinical Focus
Neurogenetics, Clinical Genetics, Marfan syndrome, Williams syndrome, Heritable connective tissue disorders
Research Interests
Functional consequences and pathogenetic mechanisms of mutations and microdeletions in human neurogenetic syndromes and mouse models. Integration of genomic information into medical care.

565 Total Publications
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Mary Hynes

Associate Professor (Research) of Biology

37 Total Publications
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Peter K. Jackson

Professor of Microbiology and Immunology (Baxter Labs) and of Pathology
Research Interests
Dr. Jackson’s lab studies how primary cilia organize hormone, metabolite, and growth factor signaling in metabolic tissues and how their disruption causes obesity and diabetes. A second focus is defining the KRAS driven secreted factor networks that rewire the tumor microenvironment in lung and pancreatic cancers to promote immune evasion and therapeutic resistance. This work is revealing new secreted drug targets and combination strategies for precision oncology and metabolic disease.

176 Total Publications
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Paul A. Khavari, MD, PhD

Carl J. Herzog Professor of Dermatology in the School of Medicine
Clinical Focus
Cancer > Cutaneous (Dermatologic) Oncology, Dermatology, General Dermatology
Research Interests
We work in epithelial tissue as a model system to study stem cell biology, cancer and new molecular therapeutics. Epithelia cover external and internal body surfaces and undergo constant self-renewal while responding to diverse environmental stimuli. Epithelial homeostasis precisely balances stem cell-sustained proliferation and differentiation-associated cell death, a balance which is lost in many human diseases, including cancer, 90% of which arise in epithelial tissues.

248 Total Publications
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Ron Kopito

Professor of Biology
Research Interests
Our laboratory use state-of-the-art cell biological, genetic and systems-level approaches to understand how proteins are correctly synthesized, folded and assembled in the mammalian secretory pathway, how errors in this process are detected and how abnormal proteins are destroyed by the ubiquitin-proteasome system.

131 Total Publications
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Frank M. Longo, MD, PhD

George E. and Lucy Becker Professor of Medicine and Professor, by courtesy, of Neurosurgery
Clinical Focus
Alzheimer's Disease, Huntington Disease, Neurology
Research Interests
Clinical interests include Alzheimer's disease and Huntington's disease and the development of effective therapeutics for these disorders. Laboratory interests encompass the elucidation of signaling mechanisms relevant to neurodegenerative disorders and the development of novel small molecule approaches for the treatment of neurodegenerative and other neurological disorders.

225 Total Publications