Orly R. Klein, MD

Clinical Assistant Professor, Pediatrics - Stem Cell Transplantation

Clinical Focus

Hematopoietic Stem Cell Transplantation
Immune Regulatory Disorders
Severe Aplastic Anemia
Leukemia/Lymphoma
Pediatric Hematology-Oncology

Academic Appointments

Clinical Assistant Professor, Pediatrics - Stem Cell Transplantation

Boards, Advisory Committees, Professional Organizations

Chair, Medical Committee, Camp Ramah Darom (2018 - Present)
Medical Advisory Board, Rally Foundation for Childhood Cancer (2017 - Present)

Professional Education

Board Certification: American Board of Pediatrics, Pediatric Hematology-Oncology (2017)
Fellowship: Johns Hopkins Medicine Pediatric Hematology and Oncology Program (2016) MD
Fellowship, National Institutes of Health, National Cancer Institute Pediatric Oncology Branch, Pediatric Hematology-Oncology (2015)
Board Certification: American Board of Pediatrics, Pediatrics (2012)
Residency: Icahn School of Medicine at Mount Sinai Pediatric Residency (2012) NY
Medical Education: Icahn School of Medicine at Mount Sinai (2009) NY

Contact

Academic oklein@stanford.edu

Administrative Contact Elizabeth Alarcon Administrative Associate elarcon@stanford.edu

Clinical (Primary)

This is the primary clinic for this clinical provider. For additional clinical locations and information, please visit the link(s) listed below in the 'Additional Clinical Info' section.

Pediatric Stem Cell Transplantation 725 Welch Rd Ste 160 Palo Alto CA 94304 Tel: (650) 497-8953 Fax: (650) 497-8101

Additional Clinical Info

Stanford Medicine Children's Health

All Publications

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Rajni Agarwal

Professor of Pediatrics (Stem Cell Transplantation)
Clinical Focus
Blood and Marrow Transplantation, Pediatric, Cell and Gene therapy, Pediatric Hematology-Oncology
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Hematopoietic Stem cell biology-created a SCID mouse model to study engraftment of cord blood derived hematopoietic cells and use of this model to develop gene transfer technology for Fanconi anemia.
Clinical research interests are to develop new protocols to reduce Toxicity from the conditioning regimens for stem cell transplants, reducing graft vs host disease, treatment of viral infections post transplant and use of manipulated HSC graft in patients who receive haplo donor transplants.

88 Total Publications
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Bone marrow transplantation (BMT) is a treatment modality which is being broadly applied to a growing number of disorders. Increasing success with BMT is offering improved survival to pediatric and adult patients with acute leukemia, chronic leukemia, lymphomas, and a variety of solid tumors as well as severe aplastic anemia.

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My research focuses on the physiolgogic and biomarker characteristics of early acute lung injury (ALI) prior to need for mechanical ventilation. While, to date no pharmacologic treatment has improved survival in ALI, following the paradigm of early goal directed therapy for severe sepsis, clinical benefit may derive from identifying patients and initiating treatment prior to the need for positive pressure ventilation (and therefore prior to meeting current study entry criteria).

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