Katharine Miller

Basic Life Research Scientist, OHNS/Research Division

All Publications

Publications (15)

All Publications (15)
Featured Publications (3)
Journal Articles (15)

Profiles With Related Publications

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Jeffrey Axelrod

Professor of Pathology
Research Interests
Genetic and cell biological analyses of signals controlling cell polarity and morphogenesis. Frizzled signaling and cytoskeletal organization.

95 Total Publications
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Nesrine Benkafadar

Instructor, Otolaryngology (Head and Neck Surgery)

12 Total Publications
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Alan G. Cheng, MD

Edward C. and Amy H. Sewall Professor in the School of Medicine, Professor of Otolaryngology - Head & Neck Surgery (OHNS) and, by courtesy, of Pediatrics
Clinical Focus
Hearing loss, Cholesteotoma, Pediatric sinus disease, Pediatric head and neck tumors, Pediatric Otolaryngology
Research Interests
Active Wnt signaling maintains somatic stem cells in many organ systems. Using Wnt target genes as markers, we have characterized distinct cell populations with stem cell behavior in the inner ear, an organ thought to be terminally differentiated. Ongoing work focuses on delineating the developing significance of these putative stem/progenitor cells and their behavior after damage.

86 Total Publications
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Gerald Crabtree

David Korn, MD, Professor of Pathology and Professor of Developmental Biology
Research Interests
Chromatin regulation and its roles in human cancer and the development of the nervous system. Engineering new methods for studying and controlling chromatin and epigenetic regulation in living cells.

265 Total Publications
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Dean W. Felsher

Professor of Medicine (Oncology) and of Pathology
Research Interests
My laboratory studies the molecular basis of cancer with a focus on understanding when cancer can be reversed through targeted oncogene inactivation.

217 Total Publications
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Andrew Fire

George D. Smith Professor of Molecular and Genetic Medicine and Professor of Pathology and of Genetics
Research Interests
We study natural cellular mechanisms for adapting to genetic change. These include systems activated during normal development and those for detecting and responding to foreign or unwanted genetic activity. Underlying these studies are questions of how a cells can distinguish information as "self" versus "nonself" or "wanted" versus "unwanted".

189 Total Publications
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Margaret T. Fuller

Reed-Hodgson Professor of Human Biology, Katharine Dexter McCormick and Stanley McCormick Memorial Professor and Professor of Genetics and of Obstetrics/Gynecology (Reproductive and Stem Cell Biology)
Research Interests
Regulation of self-renewal, proliferation and differentiation in adult stem cell lineages. Developmental tumor suppressor mechanisms and regulation of the switch from proliferation to differentiation. Cell type specific transcription machinery and regulation of cell differentiation. Developmental regulation of cell cycle progression during male meiosis.

129 Total Publications
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Nicolas Grillet, PhD

Assistant Professor of Otolaryngology - Head & Neck Surgery (OHNS)
Research Interests
We are interested in identifying the genes leading to Hearing and Vestibular impairments, and understanding their function at the molecular level.
We have a special focus on how the Hair Cells are able to detect mechanical stimulation.

29 Total Publications
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Daria Hekmat-Scafe

Advanced Lecturer

14 Total Publications
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Stefan Heller

Edward C. and Amy H. Sewall Professor in the School of Medicine and Professor of Otolaryngology - Head & Neck Surgery (OHNS)
Research Interests
Our research focuses on the inner ear, from its earliest manifestation as one of the cranial placodes until it has developed into a mature and functioning organ. We are interested in how the sensory epithelia of the inner ear that harbor the sensory hair cells develop, how the cells mature, and how these epithelia respond to toxic insults. The overarching goal of this research is to find ways to regenerate lost sensory hair cells in mammals.

125 Total Publications
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Justyna Janas

Basic Life Research Scientist, Stem Cell Bio Regenerative Med Institute

14 Total Publications
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Ron Kopito

Professor of Biology
Research Interests
Our laboratory use state-of-the-art cell biological, genetic and systems-level approaches to understand how proteins are correctly synthesized, folded and assembled in the mammalian secretory pathway, how errors in this process are detected and how abnormal proteins are destroyed by the ubiquitin-proteasome system.

129 Total Publications