Petritsch Lab Open Positions

The Petritsch lab is actively recruiting highly motivated postdoctoral trainees who are two or less years past their doctorate. The prospective candidate will participate in one or more of the following projects:

  1. Molecular and cellular mechanistic analyses of asymmetric cell division in OPCs using a candidate gene approach. Candidates are from an expression screen that was recently conducted in the laboratory. The postdoc is expected to develop new tools to study cell fate decisions in the oligodendrocyte lineage using genome editing, live cell imaging, microfluidics and single cell RNA-seq analyses. This work is expected to reveal the underlying biology for cell fate decision making in the brain and provide new insights into dysregulation of glioma cell hierarchies.
  2. Identify the role of OPCs for cellular heterogeneity in the normal brain and in brain tumors. This project emphasizes on the interactions of OPCs with the immune system, and aims to define molecular interactions between tumor cells, OPCs and the immune system to understand and overcome immune suppression in gliomas. The postdoc is expected to isolate human OPCs from fresh brain tissue (normal and tumor), analyze them by -omics methods, and establish ex vivo cultures. The postdoc will maintain transgenic animals for OPC studies to complement human data. These studies are expected to yield important insights into the underlying causes for heterogeneity, both in the normal brain, and in malignant brain tumors.

For more information, please contact Dr. Claudia Petritsch at