Knowles Lab News & Events


SynGap Research Grant Awarded

The SynGAP Research Fund announced a $130,000 grant to the Knowles Lab at Stanford University to support research on SynGAP-related intellectual disability (SRID). SRID is a rare neurodevelopmental disorder that causes severe intractable epilepsy, intellectual disability and is one of the leading genetic causes of autism.

2023 Neurobiology of Brain Disorders Award

The Knowles lab is honored and grateful to receive the 2023 McKnight Foundation Neurobiology of Disease award! The funds will be used to study neuron-to-OPC synapses in epilepsy.

Vicious Cycle: Epilepsy Seizures Could Encourage More Seizures

Seizures tend to get progressively worse over time in people with epilepsy, and a new study in mice suggests why that might be the case.

CURE Epilepsy Grant

The Knowles Lab has been awarded a grant to study the therapeutic potential for targeting myelin plasticity in Lennox-Gastaut syndrome.

CURE Epilepsy Discovery: Investigating Mechanism of the Progression of Epilepsy

New research by Dr. Juliet Knowles on the mechanisms of the progression of epilepsy that has the potential to help with future epilepsy treatments.

2022 McCormick and Gabilan Faculty Awards

Congratulations, Juliet Knowles, MD, PhD, on your 2022 McCormick Faculty Award. This award was established to support the advancement of women in medicine and/or medical research directly, or by supporting the mentoring, training and encouragement of women pursuing the study of medicine, in teaching medicine, and engaging in medical research.

Brain plasticity promotes worsening of epileptic seizures, study finds

A brain mechanism needed for learning explains why epileptic seizures become more frequent, but a finding in rodents offers hope for treatment, according to a new study.

The brain ‘learns’ to have seizures more efficiently and frequently over time, mouse study shows

Scientists found that mice and rats that suffered from seizures commonly seen in people with epilepsy developed changes in the wiring of their brains that advanced the disease. A closer look showed that the cementing of these signals was driven by a process that also supports learning, memory, and attention.


Knowles lab members attended the 2023 American Epilepsy Society meeting in Orlando Florida. Congratulations to Kala Nair, Belen Perez-Ramirez and Veronica Alonzo for their excellent research presentations

Third Annual Lab Dinner at the Knowles House

First Annual Knowles Lab Lake Tahoe Ski Trip, February 2023

1/31/2023: Lab Hike in Portola Valley

1/19/2023: Knowles Lab Work Retreat - Lunch at the Stanford Faculty Club

6/13/2022: Lab lunch to welcome our summer students

6/2022: A bittersweet farewell to Ankita and Sydney! These two superstars are headed off to medical school. We wish them all the best!

5/2022: Celebrating the publication in Nature Neuroscience, of our work on maladaptive myelination in epilepsy

5/2022: Surprise birthday party by this amazing crew! So much fun!

6/2021: Inaugural Lab Party!

5/2021: Congratulations to Knowles Lab member Tristan Saucedo, who received a 2021 Stanford Major Grant to support his summer research project on myelination and EEG coherence. Tristan also received a Stanford BioX Undergraduate Research Fellowship in 2020.

4/2021: Congratulations to Knowles lab member Haojun (Lucy) Xu, whose original children’s book, Good Night Lucy: The Virus Fighter, was published in Japan. The book, which will help children (and possibly adults, too) understand how viruses and the immune system interact, is being translated into multiple languages.

3/2021: The Knowles lab research on maladaptive myelination in epilepsy was recognized by the Johns Hopkins Stroup Award for Pediatric Epilepsy Research!

  • 5/2020: The Knowles lab research on maladaptive myelination in epilepsy was recognized by the Child Neurology Foundation Elterman Award!