Aromatase Inhibitor Growth Study

Clinical Study Details

Title

Aromatase Inhibitor Growth Study

Description

This clinical trial uses anastrozole (1 mg by mouth daily) in adolescent males for 1-3 years during puberty to reduce estrogen levels toward a goal of possible gain in final adult height.

Inclusion Criteria

  1. At least 10 years of age
  2. Have a Bone age of 14 years or younger
  3. Be in puberty - LH greater than 0.3 AND Testosterone greater that 15
  4. Height less than the 5th percentile OR PAH more than 10cm BELOW the MEASURED (adjusted) midparental height (Best if BOTH criteria are met)

Exclusion Criteria

  1. Is a female
  2. Primary testicular failure
  3. GH therapy is NOT an exclusion (assure GH consent is ALSO signed

More Info

If you're interested in learning more about this study, please reach out to the study contact listed on the right. You may also download the consent form, assent form, and any other documents linked on the right.


Study Contact

Kirk Neely, MD

650-723-5791

ekneely@stanford.edu

Study Documents