January 10 Jan 10
2020
Friday Fri

Pediatric Grand Rounds (CME): Lessons From Human Genetics for Diabetes: From Bench to Bedside

Anna Gloyn, DPhil

This lecture will provide an overview on the genetic basis for diabetes focusing on where genetic discoveries have impacted clinical care and management.

Speaker

Anna Gloyn, DPhil 

Professor of Molecular Genetics & Metabolism 
University of Oxford
Oxford Centre for Diabetes Endocrinology & Metabolism, Churchill Hospital

Session Description

This lecture will provide an overview on the genetic basis for diabetes focusing on where genetic discoveries have impacted clinical care and management.   The value of human models for understanding human disease will be discussed and the implications our understanding of the genetic basis of rare forms of diabetes has for understanding more complex and common forms of diabetes (e.g. T2D) which are increasingly more prevalent in paediatric clinics will be discussed.

Education Goals

  • An appreciation of the power of human genetics to provide fundamental insights into human metabolism
  • Recognition that there are rare monogenic subtypes of diabetes, many of which present in children and young adults
  • Challenges in differentiating the diagnosis of individuals with rare monogenic diabetes from T1 and T2 diabetes
  • Subjects with KCNJ11 activating mutations can be treated with oral sulphonylureas rather than insulin injections

Location

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Lucile Packard Children's Hospital, West Building Auditorium

725 Welch Road
Stanford, CA 94304
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CME Credit

Accreditation

The Stanford University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation

The Stanford University School of Medicine designates this live activity for a maximum of 1.00 AMA PRA Category 1 Credit(s)TM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Cultural and Linguistic Competency

California Assembly Bill 1195 requires continuing medical education activities with patient care components to include curriculum in the subjects of cultural and linguistic competency.  The planners and speakers of this CME activity have been encouraged to address cultural issues relevant to their topic area. The Stanford University School of Medicine Multicultural Health Portal also contains many useful cultural and linguistic competency tools including culture guides, language access information and pertinent state and federal laws. You are encouraged to visit the portal: http://lane.stanford.edu/portals/cultural.html

Contact Stanford Center for Continuing Medical Education for CME credit transcript. Email Magna Patel, RSS Manager at magna@stanford.edu or stanfordcme@stanford.edu.

Planner and Faculty Disclosure to Learners

In accordance with the standards of the Accreditation Council for Continuing Medical Education (ACCME), all speakers, planners and/or persons who can influence the CME content must disclose to learners any relationships with commercial interests providing products or services that are relevant to the content of the presentation. The following individual(s) HAVE indicated the following relationships:

Speaker:

Anna Gloyn, DPhil

Spouse Employment by commercial interest- Genentech

Advisory board member with monetary and/or other compensation- Diabetologia and Endocrine Reviews

Fees for speaker’s bureaus received directly from commercial interest - Novo Nordisk

Contracted Research (Self, Spouse/Partner) - Novo Nordisk

Ownership interest (Spouse/Partner)- Genentech

Consulting Fees (Self, Spouse/Partner) - Merck, Pfizer, Novo Nordisk

Planner

Bertil Glader, MD
Contracted Research: Agios

The following speakers, planning committee members and/or persons who can influence CME content have indicated they have NO relationships with commercial industry to disclose relevant to the content of this CME activity:

Course Director

Alan Schroeder, MD, Associate Chief for Research, Division of Pediatric Hospital Medicine

Planners

Mary Leonard, MD, MSCE, Chair Department of Pediatrics
Matthew Porteus, MD, PhD, Associate Professor, Division of Stem Cell Transplantation and Regenerative Medicine
Neville H. Golden, MD, Chief, Division of Adolescent Medicine
Lisa Chamberlain, MD, MPH, Associate Professor, General Pediatrics
Minnie Dasgupta, MD, Chief Resident, Pediatric Residency Program