PATHOLOGY GRAND ROUNDS

The Pathology Grand Rounds is open to those affiliated with Stanford University Medical Center and invited guests only. The objective is to increase knowledge in the field of Pathology. There is no commercial support received for this course unless otherwise specified. These lectures are hosted by Stanford Pathology Faculty.

Some Grand Rounds Lectures may be available in person and/or hybrid via ZOOM. Please contact Annie Vo at annie.vo@stanford.edu or 650-725-3940 for more information.

Dr. Jiang Wu obtained her bachelor’s degree in Genetics from Fudan University and Ph.D. degree in Molecular Biology from the University of Texas at Austin. She carried out postdoctoral training in the Department of Pathology and Developmental Biology in Stanford University with Dr. Gerald Crabtree. During her postdoc training, she developed a state-of–the-art proteomic approach and discovered subunit composition changes of chromatin remodeling complexes during neural differentiation. Using genetic manipulations, she demonstrated their specific functions in neural progenitors and neurons. Dr. Wu is currently an Associate Professor and Virginia Murchison Linthicum Scholar in Medical Research in the Department of Physiology at UT Southwestern Medical Center.     Her research focuses on how chromatin states and epigenetic regulators control gene expression in response to signals during neural development and tumorigenesis. Using the mammalian developing brain as a model system, she combines the current genomic and proteomic techniques, as well as the classic biological approaches to investigate the epigenetic mechanisms regulating neural developmental disorders and pediatric brain cancers. One project in her lab uncovers critical and diverse epigenetic mechanisms regulating Sonic hedgehog (SHH) signaling and medulloblastoma. The second project involves the molecular function of the neuron-specific chromatin remodeling complexes in regulating neuronal activity-induced enhancer activation and gene expression.