Pathology Art

2024 Pathology Research Retreat


1st Place Prize: Your winning image premium frame mounted on a metal plate for your own piece of hangable art from ShinyPrints

 

Click or scan to vote!
1st, 2nd, and 3rd choice
[Voting available Oct 7-11]

Alejandra Torres, MS
Research Staff
Schuele Lab

"A Glimpse into the Mind"

Neurons in a mesencephalic coronal section of a mouse model using COdetection by INDEXing technology (CODEX).

— Alejandra

Basil Baccouche,
MPhil

Student

"Pilau"

While imaging a section of myocardial tissue, an artifact sliced off the wall emerged as an "island" off of the ventricular wall. In the final image it struck me how topographically similar it appeared to the island of Pilau off the coast of Rafraf, Tunisia, where my family originated. The image here shows the histology slide and the map of Tunisia side-by-side for comparison.

— Basil

Jorge Sanz-Ros, MD, PhD
Post Doc
Cobos Lab

"Brain Seaweeds"

In our lab we are currently studying the interaction between different brain cell types and its role in neurodegeneration. To achieve this, we are using different AAV-based strategies that enable labeling of specific cell types in the brain. In this 3D projection of mouse cortex, we can see layer 1 interneurons (green) interacting with the apical dendrites of excitatory neurons (white), GFAP+ layer 1 astrocytes (violet) and microglia (red).

— Jorge

Rachel Frauches, MD
Research Associate
Lin Lab

"Macrophages Surfing in the Geographic Atrophy Wave"

The prevalence of Geographic Atrophy (GA) in the United States is estimated to be about 1 million people.  This condition is marked by the atrophy of outer retinal tissue, retinal pigment epithelium (RPE), and choriocapillaris, leading to impaired central vision. The histological features and immunohistochemical patterns of inflammation in GA within human eyes are not well understood. The red surfboard in the image highlights a macrophage by CD163 immunohistochemistry. Our findings suggest that macrophage-mediated inflammation may play a role in RPE degeneration during GA pathogenesis.

— Rachel

Yuhan Bi, PhD
Post Doc
Butcher Lab

"Homing T Cells"

A set of images to show T cell homing to non-mucosal organs including Lung, trachea, Gallbladder, etc. I also provide images to show blood vessels of lymphoid tissues. These images are whole-mount staining with our cutting-edge technology of injecting antibodies I.V. to light up the blood vessels.

— Yuhan

Alex Chang-Graham MD, PhD
Resident AP/CP

"Don't Drink and Divide"

A compilation of mitotic figures from histologic sections of specimens with cancer.

— Alex

Goonho Park, PhD
Instructor

"Neuronal Serenade"

This image captures the intricate dance between the CA1 and CA2 regions of a brain organotypic slice culture. The red fluorescent signal, driven by a tomato-expressing virus, highlights neurons in the CA2 region, while the green fluorescence marks the CA1 region. The projection of these neurons towards each other symbolizes a profound connection as if they are reaching out to share and communicate—a visual representation of the intricate communication and connection that underlies cognitive function.

— Goonho

Marcus Schonemann, PHD
Research Staff

"Cellular Olympics – The Relocalization Event"

Parkinson’s Disease (PD) is a progressive neurodegenerative disorder.  Mutations in the LRRK2 Kinase and its implied signal transduction pathway, are associated with Hereditary PD. Targeting the kinase domain of the G2019S variant of LRRK2 with selective small molecule TypeI inhibitors provides an avenue to investigate the role of LRRK2 in PD. We are using a well established In Vitro Cell Culture model system to visualize target engagement by the selective inhibitor which results in relocalization of the LRRK2-GFP reporter protein from the cytoplasm (pseudocolored-orange) to a cytoskeletal “like” structure we describe as “Skeines” (pseudo-colored green). The actual relevance of this observation in a clinical setting remains to be determined. In the spirit of the recent Olympic Games in Paris France, I give the artwork the title of “Cellular Olympics”, let the relocalization game begin, with the hope to find a cure for PD.

— Marcus

Syed Usman Enam
Student
Fire Lab

"Copy/Haste"

This is a commentary piece on data manipulation. Shown are principal investigators who are authors on papers with suspected duplicated western blots. The resepective suspected blots are represented as blindfolds and cited on the border of the piece. This piece is not meant to be an indictment of the individuals shown, most of whom, in fact, may not have been privy to any potential data manipulation. Rather, this piece was created for a class final project in as short a time as possible, for maximal possible "flashiness", all while copying a different artist's style. The purpose was to mirror what goes on in the mind of someone who manipulates scientific results. It is meant also to evoke facets of Warhol's artistic philosophy.

— Syed