Welcome to the 2023 Stanford Pathology Research Retreat. This event has passed but read about the results of the Retreat below.
Congratulations to over 460 students, postdocs, residents, fellows, staff, and faculty who participated in our annual retreat on Friday, November 3, 2023. A very rewarding day was spent in a terrific venue with close colleagues and good friends learning of the amazing quality and breadth of research happening in our department. There were 120 scientific presentations and 11 pathology art submissions.
The purpose of our retreat is to allow Stanford Pathology members to become more familiar with the research that is being conducted in the Department, including basic, translational, and clinical projects. We hope this will facilitate new opportunities for collaborative studies and research training, and enhance prospects for additional funding of such activities.
Cash prizes were awarded in 6 categories:
- Students
- Postdoctoral Fellows
- Research Associates
- CP Residents
- AP Residents
- Clinical Fellows
Winners of the 2023 Stanford Pathology Research Retreat
[read more about them below]
Students
5 prizes awarded
Elsa Balfe, BS [Abstract #62]
"New Hope in Treating Chronic Inflammation and Fibrosis- CAR-T Mediated Immunotherapy for Liver Cirrhosis and ILD"
Alex Muselman, BS [Abstract #81]
"Viral Infection Primes Microglia and Induces CVhronic Neuroinflammation"
Zhuang (Max) Miao, PhD [Abstract #90]
"Investigating the Role of TCR Signal Strength in T Cell Differentiation and Exhaustion"
Noah Greenwald
[Abstract #95]
"The Temporal Influence of the Tumor Microenvironment in Response to Checkpoint Blockade"
Drew Galls [Abstract #52]
"The (mis)behavior of E. coli RNA Polymerase on RNA Replicons: Studies on RNA Replication by a Cellular RNA Polymerase"
Postdocs
9 prizes awarded
Cristabelle De Souza, PhD [Abstract #12]
"Targeting CD63 as a Novel Fibrogenic Immune Target for the Treatment of HCC and NASH"
Mohammad Ovais Aziz-Zanjani, Phd [Abstract #49]
"Identification of Phosphorylation Regulatory Mechanisms Driving Beta Cell Insulin Secretion"
Sijie Wang, PhD
[Abstract #59]
"Development of Cyclic Covalent Inhibitors Targeting SARS-CoV-2 spike/ACE2 Protein-Protein Interaction using Phage Display"
Kazuma Sekiba, MD, PhD [Abstract #23]
"Defining Pathways for Microbiome-derived Molecules in Human Circulation: A Genes-to-Metabolites Approach"
Shuke Xiao, PhD
[Abstract #74]
"A Hibernation-induced Molecule that Prevents Hypoglycemia in Bears"
Zhiwei Zhou, PhD
[Abstract #18]
"Plasma metabolomics uncovers characteristic metabolic aberrancies in early-onset Crohn's Disease"
Akila Parvathy Dharshini Sankaraeswaran, PhD [Abstract #51]
"Identifying Resistant and Vulnerable Neuronal Populations in the Human Alzheimer's Disease Neocortex by Single-nuclear RNA Sequencing"
Korina Steinbergs, MD [Abstract #91]
"Novel Blindness-deafness Syndrome Reveals Sensorineural Hearing Loss caused by Variants in ATF6"
Inna Averbukh, PhD [Abstract #75]
"A Spatially Resolved Timeline of the Human Maternal–fetal Interface"
Research Associates
Yuanyuan Liu, PhD [Abstract #35]
"In Vitro Reconstitution of a Seven-step Pathway for Anaerobic Uric Acid Metabolism"
Kausalia Vijayaragavan-Bossé, PhD, MSc
[Abstract #36]
"Single-cell Spatial Proteomic Imaging of Metabolic Changes in Human Neuropathology"
C. Alejandra Morato Torres, MS [Abstract #102]
"Robust dCas9-mediated Downregulation of Alpha-synuclein in a Parkinson’s Mouse Model"
Linh Nguyen [Abstract #86]
"Characterizing the Functions of SMARCB1 in Translation"
AP Residents
1 prize awarded
Sheren Younes, MD, PhD [Abstract #10]
"Spatial Phenotyping of Nodular Lymphocyte Predominant Hodgkin Lymphoma in Transition to Diffuse Large B-Cell Lymphoma"
CP Residents
2 prizes awarded
Priscilla Yeung, MD [Abstract #16]
"Study of Patient Serum Monoclonal Proteins by Biolayer Interferometry coupled with High-Resolution Mass Spectrometry"
Theodore Roth, MD, PhD [Abstract #100]
"CRISPR-All: A Unified Genetic Perturbation Language in Human Immune Cells"
AP/CP Residents
3 prizes awarded
Paul Wadsworth, MD, PhD [Abstract #4]
"Multi-Omics Profiling of Skin Biopsies of Patients with Sclerodermatous Graft-Vs-Host Disease Suggests Therapeutic Potential of Targeting Don't Eat Me Signals"
Alex Chang-Graham, MD, PhD [Abstract #19]
"Detection of Adenovirus in Formalin-Fixed Paraffin-Embedded Tissue by qPCR Compared to Immunohistochemistry"
Ben Dulken, MD, PhD [Abstract #9]
"Multiplexed immunofluorescent imaging to interrogate the tumor microenvironment of colorectal adenocarcinoma"
Clinical Fellows
2 prizes awarded
Rachel Frauches, MD [Abstract #69]
"Light Microscopic Comparison between Guttae containing Fuchs' and Non-guttae Fuchs' Endothelial Dystrophy"
Rabia Bhalli, MD
[Abstract #37]
"Invasive Mammary Carcinoma with Secretory Carcinoma-Like Features: Is ETV6::NTRK3 Definitional?"
1st Place
Steffen H Raun, PhD
Postdoc, Long Lab
"Running the Strings of Exercise"
Exercise has a plethora of health benefits, which we are still trying to understand at a molecular level. This artwork is based on the work led by postdoctoral researcher Wei Wei, PhD, where he and the team described how different tissues and organs secrete very different proteins and peptides during exercise. Each string represent an organ, where the strings move in harmony during exercise to elicit the health benefits of physical activity. The person running the lines is small, as an indication of how little we know about the molecular landscape of exercise. The artwork was drawn as a suggestion for the cover of the journal, where the work is now published.
— Steffen
2nd Place
Philip Bulterys, MD, PhD
Clinical Fellow
"Flow Cytometry Savanna"
This was inspired by seeing a distinct elephant shape while analyzing clinical flow cytometry data. Pathology is a visually stunning field, and flow cytometry is no exception!
— Phil
3rd Place
Sarah Frail
Researcher, Yeh Lab
"Inkblot Biota"
From the crystal shells of diatoms to the complex morphology of apicomplexans, the microbial world is full of diverse beauty. In this piece, we allude to the Victorian era practice of diatom arranging by producing our own composition of diatoms, algae, and apicomplexan parasites stamped into a symmetric pattern. Each stamp was hand-carved in rubber. The pattern was created collaboratively by different members of the lab and department during a social hour. This selection is just a few of our favorite model systems and their cousins, and we hope it represents the diversity, interaction, and intricacy of your favorite biology, too.
— Sarah
Preview Abstracts
View all presenter's abstracts for the week of October 27 thru November 3, 2023
[The preview session has passed]
2023 Schedule
[This event has passed]
Registration OPENS for all |
FRIDAY, JUNE 30, 2023 |
Abstract, poster, video, and pathology artwork submission portals OPEN (Poster Presenters) |
FRIDAY, JUNE 30, 2023 |
| Registration CLOSES for all! (Attendees & Presenters) | WEDNESDAY, SEPTEMBER 20, 2023 • 5 pm PST |
| Abstract, poster, video, and pathology artwork submission portals CLOSED! (Poster Presenters) | FRIDAY, OCTOBER 13, 2023 • 5 pm PST |
Online preview of poster presenter information, abstracts, videos, & pathology artwork |
OCTOBER 27 thru NOVEMBER 3, 2023 |
| THE RETREAT | FRIDAY, NOVEMBER 3, 2023 • 9:00 am-4:30 pm |
Location
[*TAKE NOTE: LOCATION HAS MOVED FROM LI KA SHING TO NEW LOCATION!]
This year's retreat will be held at the David and Joan Traitel Building of Hoover Institution located at 435 Lasuen Mall, Stanford CA 94305.
Friday, November 3, 2023: 9:00 AM - 4:30 PM
David and Joan Traitel Building
of Hoover Institution
435 Lasuen MallStanford, CA 94305
*Due to unanticipated record attendance registration, this year's Pathology Department Research Retreat has relocated to the David and Joan Traitel Building of Hoover Institution (this event was originally planned to be held at Li Ka Shing Center for Learning and Knowledge). Our date has remained the same, Friday, November 3rd, 2023. We chose this location as it can accommodate the number of attendees and is a quick walk from the Lane Building. This decision was to ensure we can accommodate all our Pathology Faculty, Staff, Students, and Trainees in one location. We did not anticipate this much excitement, the number of submitted abstracts, registered attendees, and overall growth in our Pathology community. We look forward to seeing you at the retreat!
Previous Winners
Students
Mary Defeo, BS (Abstract #45)
"Bacterial production of the aryl-hydrocarbon receptor ligand, indole acetic acid, and its role in gut microbiota and host metabolism"
John Bennett, BS (Abstract #32)
"Mixed Alkyl/Aryl Phosphonates as Bioisosteres of Phosphate Electrophiles Identify a Novel Essential Serine Hydrolase in Plasmodium falciparum"
Maxim Zaslavsky (Abstract #54)
"Disease diagnostics using machine learning of immune receptors"
Rachel Ungar, BS (Abstract #21)
"Functional impact of rare variants and sex across the x chromosome and autosomes"
Sai Gourisankar, BA, BS (Abstract #64)
"Rewiring Cancer Drivers to Activate Apoptosis"
Amanda Wiggenhorn, BS (Abstract #57)
"Capped peptides are a large family of blood-borne signaling molecules"
Meelad Amouzgar, MS (Abstract #26)
"Supervised dimensionality reduction for exploration of single-cell data by HSS-LDA"
Lina Mohamad (Abstract #65)
"Testing T-Cells From Multiple Donors Simultaneously"
Postdocs
Laetitia Coassolo, PhD, PharmD
(Abstract #3)
"Tissue-based human prohormone prediction identifies an anti-obesity BRINP2-derived peptide"
Kazuma Sekiba, MD, PhD (Abstract #48)
"Unbiased mapping of gut microbial pathways that contribute to human chemistry"
Matteo Guerra, PhD (Abstract #10)
"Erythropoietin (EPO) programs macrophages to suppress antitumor immunity in hepatocellular carcinoma"
Matthew McCoy, PhD (Abstract #49)
"Gene size expansion during nervous system evolution"
Laurin Heinrich, PhD (Abstract #67)
"Investigating genes within the 22q11.2 deletion region as potential risk factors for Parkinson's disease in human iPSC models"
David van IJzendoorn, MD, PhD
(Abstract #46)
"Interactions in CSF1-driven Tenosynovial Giant Cell Tumors"
Maria Dolores Moya-Garzon, PhD
(Abstract #71)
"A ketosis inducible metabolite linked to body weight and energy balance"
David Kung-Chun Chiu, PhD (Abstract #10)
"Erythropoietin (EPO) programs macrophages to suppress antitumor immunity in hepatocellular carcinoma"
Jie Pan, MD, PhD (Abstract #4)
"A new deletion in CSF1R in adult-onset leukoencephalopathy with axonal spheroids and pigmented glia"
Chris McGinnis, PhD (Abstract #31)
"Temporally-resolved scRNA-seq atlas of PyMT mouse lungs reveals tumor-mediated reprogramming of both infiltrating and tissue-resident myeloid cells during metastatic progression"
Connie Fung, PhD (Abstract #41)
"Tuft cells mediate commensal remodeling of the small intestinal antimicrobial landscape"
Research Associates
Andrey Krokhotin, PhD (Abstract #60)
"Rewiring Cancer Drivers to Activate Apoptosis"
Patricia Favaro, PhD (Abstract #15)
"Unraveling human hematopoietic progenitor cell diversity through association with intrinsic regulatory factors"
Faria Zafar, MS (Abstract #62)
"Alpha-synuclein gene dosage affects neuronal differentiation and cellular stress in human stem cell model of Parkinson’s Disease"
Karen Artiles, PhD (Abstract #16)
"High throughput genomic and transcriptomic approaches to investigate causes of a Chronic Kidney Disease of unknown etiology (CKDu) in Sri Lanka"
AP Residents
Diane Libert, MD (Abstract #1)
"Effusion tumor cell (ETC) detection from cytology samples following long-term storage" (Please note: this is 1 of 2 abstracts submitted by Diane)
Clinical Fellows
Rebecca Rojansky, MD, PhD (Abstract #27)
"Digital Spatial Profiling Reveals Spatial Heterogeneity in Nodular Lymphocyte-Predominant Hodgkin Lymphoma"
CP Residents
Alex Chang-Graham, MD, PhD
(Abstract #39)
"Clinicopathologic Features of Mucinous Adenocarcinoma Arising in Low-Grade Appendiceal Mucinous Neoplasm"
1st Place
Leila DeSchepper, BS
Student, Howitt Lab
"Orgaynoids"
When I first saw this organoid under the lens of a Zeiss confocal, I was transported to another world, one where cytokine-treated colon organoids float blissfully in a sea of Vectashield, their mucus blooms frozen in eternity, waiting to swish away unsuspecting predators. Under the scope, the mucus appears in vibrant orange, spreading its tendrils beyond the organoid's epithelium, where cell nuclei are marked by DAPI and F-actin by phalloidin. Though organoids form a small part of my research on cell interactions in the intestinal epithelium, they are one of my favorite systems, in no small part because of the excitement and suspense I feel each time I turn on the scope, illuminating anew the secrets hidden within the ethereal world of organoids.
— Leila
2nd Place
Philip Bulterys, MD, PhD
Resident AP/CP
"At Slides Edge"
It's hard not to anthropomorphize the little shapes that mounting media makes at histology slide's edge. Always there, never seen. Living out a complex lifecycle replete with life's ups and downs.
— Philip
3rd Place
Sheren Younes, MD, PhD
Research Associate
"Lymphoma Leopard"
Multiplex tissue image, CODEX-MAV software.
— Sheren
Students
Wei Wei (Abstract #2)
Cell type-selective secretome profiling in vivo
Julia Tanzo, BS (Abstract #26)
Vitamin D binding protein is a plasma carrier of N-acyl amino acids
Nicholas Hughes (Abstract #40)
A compact and inducible Cas12a barcode system for simultaneous single-cell lineage recording and transcriptional profiling
Veronica Li, BS (Abstract #21)
N-lactoyl phenylalanine as a molecular transducer of physical activity
YeEun Kim, BS (Abstract #33)
A highly multiplexed single cell proteomic screen reveals the phenotypic and functional landscape of the human lympho-myeloid differentiation axis
Postdocs
Thanaphong Phongpreecha, PhD (Abstract #6)
Single-cell peripheral immunoprofiling of Alzheimer’s and Parkinson’s diseases
Oliver Wirz, PhD (Abstract #46)
Serological profile of COVID-19 convalescent plasma donors and effects in transfusing COVID-19 patients
Meng (Gemma) Zhao, PhD (Abstract #13)
Identification of a novel extracellular regulator of hepatic fructose transport
Research Associates
Sandra Nielsen, PhD (Abstract #10)
Human B cell clonal expansion and convergent antibody responses to SARS-CoV-2
Katharina Roeltgen, PhD (Abstract #37)
Defining the features and duration of antibody responses to SARS-CoV-2 infection associated with disease severity and outcome
AP Residents
Joshua Wheeler, MD, PhD (Abstract #5)
RNA-binding proteins direct myogenic cell fate decisions
Clinical Fellows
Steven Baker, MD, PhD (Abstract #18)
Lung angiotensin-converting enzyme 2 (ACE2) expression increases with age in patients requiring mechanical ventilation
CP Residents
Hannah Wang, MD (Abstract #20)
SARS-CoV-2 nucleocapsid plasma antigen for the diagnosis and monitoring of COVID-19
Student
Pagé Goddard, BS (Abstract #32)
Transcriptional diversity in the African functional genomics resource