Stanford Medicine scientists have rebuilt, in laboratory glassware, the neural pathway that sends information from the body’s periphery to the brain, promising to aid research on pain disorders.

Stanford Medicine research on Timothy syndrome — which predisposes newborns to autism and epilepsy — may extend well beyond the rare genetic disorder to schizophrenia and other conditions.

Combining two cutting-edge technologies, researchers revealed the impact of a multitude of genes that are associated with neurodevelopmental disorders, including autism, but whose effects on human brain development were previously unknown.

Lab-grown clusters of human brain cells integrate so well into young rats' brains they enable researchers to study neurodevelopmental disorders' molecular and circuit underpinnings.

A Stanford Medicine team used human stem cells to assemble a working nerve circuit connecting brain tissue to muscle tissue. The research could enable scientists to better understand neurological disorders that affect movement.

A common genetic deletion boosts the risk for schizophrenia by 30-fold. Generating nerve cells from people with the deletion has showed Stanford researchers why.

Low oxygen levels during brain development may cause particular cells to differentiate too soon, a Stanford-led study found.

Studying human oligodendrocytes, which provide insulation for nerve cells, has been challenging. But a new way of generating stem-cell-derived, three-dimensional brain-cell cultures is paying off.

The grant will help Stanford investigators find out if variants in many different autism-linked genes trigger the condition by affecting molecular pathways and cellular processes.

Stanford investigators fused two stem-cell-derived neural spheroids, each containing a different type of human neuron, then watched as one set of neurons migrated and hooked up with the other set.

Researchers have figured out how to create spheres of neuronal cells resembling the cerebral cortex, making functional human brain tissue available for the first time to study neuropsychiatric diseases such as autism and schizophrenia.