Stanford Science and Research Team

Cellular Immunology in PANS

Elizabeth Mellins, MD
Monocyte Research

  • Professor
  • Stanford Children's Health
  • Pediatrics Human Gene Therapy

Catherine Blish, MD, PhD

HLA in PANS

  • Professor
  • Stanford University School of Medicine
  • Infectious Disease

David Lewis, MD 
Immmunology Research

  • Chief & Professor
  • Stanford Children's Health
  • Pediatric Allergy, Immunology & Rheumatology

Naresha Saligrama, PhD

  • Assistant Professor of Neurology
  • Washington University St.Louis
  • The Saligrama lab is dedicated to understanding the adaptive immune responses in health and neurological disorders. He began T cell work in PANS during his time as a postdoc in Dr. David Lewis's lab, and continues this research in his lab at Washington University, St Louis. 

Holden Maecker, PhD 
CyTOF and Cytokine Research

  • Director of Human Immune Monitoring Center
  • Stanford Children's Health
  • Microbiology & Immunology

Autoantibodies in PANS

PJ Utz, MD
Immunological Research

  • Professor
  • Stanford Medicine
  • Immunology and Rheumatology

Christopher Bartley, MD, PhD

  • Adjunct Instructor-HCOMP, Psychiatry
    UCSF Weill Institute for Neurosciences
  • University of California, San Francisco
  • Dr. Bartley is a physician-scientist who oversees the Immunopsychiatry Clinic in the Department of Psychiatry at University of California, San Francisco. In that clinic he provides consultations for patients with immune-related psychiatric symptoms. As a scientist, Dr. Bartley works closely with his neuroinflammatory colleagues in the Department of Neurology to discover new brain-targeting antibodies that may be relevant to psychiatric and/or neurologic syndromes. Dr. Bartley research utilizes CSF from our Stanford patient cohort.

Christopher Pittenger, MD, PhD, FAPA, FANA

  • Professor of Psychiatry; Assistant Chair for Translational Research, Psychiatry; Director, Yale OCD Research Clinic; Director, Neuroscience Research Training Program, Yale Department of Psychiatry
  • Yale
  • Dr. Pittenger researches the basal ganglia (regulator of motor and behavioral function) and the consequences of its dysfunction in various diseases like obsessive-compulsive disorder, tics, and Tourette syndrome. He and his colleagues have discovered autoantibodies against neurons within the basal ganglia which alter the behavior of the brains neural network and is likely involved in driving PANS symptoms. His work has included specimens from our patient cohort.

Madeleine Cunningham, PhD

  • George Lynn Cross Research Professor
  • Oklahoma State University
  • Dr. Cunningham's laboratory has been highly focused on the investigation of molecular mimicry, autoimmunity and infection in inflammatory heart disease for the past 20 years. A second focus of the laboratory is on the study of autoimmunity and behavior which is manifest in diseases such as Sydenham's chorea following group A streptococcal infection. 

Genetics in PANS

Carlos Bustamante, AB, AM, PhD 
Genetics and Microbiome Research

  • Professor
  • Department of Genetics & Biology

Agnes Kalinowski, MD

C4 Gene Research

  • Clinical Instructor
  • Stanford University School of Medicine
  • Psychiatry and Behavioral Sciences

Fereshteh Jahaniani, PharmD, PhD

Chronic Fatigue in PANS

  • Research Associate
  • Stanford University School of Medicine
  • Stanford Center for Genomics & Personalized Medicine

Mike Snyder, PhD

Genomics Research

  • Professor
  • Stanford University School of Medicine
  • Genetics

David Stevenson, MD

  • Professor
  • Stanford University School of Medicine
  • Pediatrics

Jill Hollenbach, PhD, MPH

  • Associate Professor, Neurology
  • University of California, San Francisco
  • The Hollenbach Lab specializes in analysis of the extremely polymorphic human leukocyte antigen (HLA) and killer immunoglobulin-like receptor (KIR) immunogenetic systems. In addition to their critical role in transplantation, over 100 infectious, autoimmune and pharmacological disease phenotypes and cancers are associated with genetic variation of HLA and KIR, which also have functional interaction with one another. She is running analyses on a cohort of our patient specimens.

Marcelo Fernandez Vina, PhD 
HLA Research

  • Professor
  • Stanford Children's Health
  • Pathology

Ronald Davis, PhD
Genetics

  • Professor
  • Stanford Children's Health
  • Biochemistry & Genetics

Alex Urban, PhD

C4 Gene Research

  • Associate Professor
  • Stanford University School of Medicine
  • Psychiatry and Behavioral Sciences, Genetics

Neuroimaging in PANS

Allan Reiss, MD

Psychiatry and Radiology

  • Professor
  • Stanford University School of Medicine and Stanford Children's Health
  • Psychiatry and Behavioral Sciences

Kristen Yeom, MD

Neuroradiology Research

  • Associate Professor
  • Stanford Children's Health
  • Pediatric Radiology

Allison Vreeland, PhD

MRI/Imaging Research

  • Postdoctoral Scholar
  • Stanford University School of Medicine
  • Pediatric Radiology and Psychology (Reiss Lab)

Microbiome and Related Proteomics

Omar Cornejo, PhD

  • Associate Professor in the School of Biological Sciences at Washington State University.
  • Washington State University
  • Dr. Cornejo is a population geneticist specializing in infectious diseases and human genetics. He is primarily interested in how microbes and pathogens have evolved and shaped each other's genomes.  Dr. Cornejo is a continual participant in our PANS basic science team and is lending his expertise to help pave the way for oral and gut microbiome projects.

Sarkis Mazmanian, PhD

Microbiome-Based Therapeutics for Autism
  • Luis B. and Nelly Soux Professor of Microbiology, Caltech Investigator, Heritage Medical Research Institute
  • Cofounder and a board member of Axial Therapeutics.

Juliette Madan, MD, MS

  • Associate Professor, Pediatrics, Epidemiology, Quantitative Biomedical Data Science
  • Dartmouth
  • Dr. Madan joined the Dartmouth Children’s Center as its Clinical Research Director, expanding the microbiome research program to investigate the relationship between early microbiome development and health outcomes, including neurodevelopmental and neuropsychological outcomes (the gut-brain axis). Recent expansion of this work has included expansion of translational research as part of her Directorship of the Psycho-Immunology and Neurology Group at Dartmouth within Child Psychiatry.

Stewart Campbell, PhD

Microbiome based therapeautics 

  • CEO, Axial Therapeautics

Noga Or-Geva, PhD

Research in Immunophenotyping

  • Postdoctoral Research Fellow
  • Stanford University School of Medicine
  • Neurology & Neurological Sciences

Lawrence Steinman, MD
Neuroimmunology Research

  • Professor
  • Stanford Children's Health
  • Pediatrics & Neurology & Neurological Sciences

Bio-Informatics

Carlos Bustamante, AB, AM, PhD 
Genetics and Microbiome Research

  • Professor
  • Department of Genetics & Biology

Omar Cornejo, PhD

  • Associate Professor in the School of Biological Sciences at Washington State University.
  • Washington State University
  • Dr. Cornejo is a population geneticist specializing in infectious diseases and human genetics

Corrado Priami 

  • Professor of Computer Science, University of Pisa
  • Director SPARK Program Pisa
  • CTO Vydiant 

Clinical Research

Cynthia Kapphahan, MD, MPH

Eating Restriction in PANS

  • Clinical Professor
  • Stanford University School of Medicine
  • Pediatrics, Adolescent Medicine

Margo Thienemann, MD
Director of Psychiatry Services &
PANS Psychiatrist (expertise in O.C.D.)

  • Clinical Professor
  • Stanford Children's Health
  • Psychiatry & Behavioral Sciences -
    Child & Adolesecent Psychiatry 

Erin Masterson, PhD, MPH

  • Epidemiologist
  • University of Washington, Seattle
  • Dr. Masterson's research is broadly focused on the developmental origins and social determinants of health. Specifically, she is developing methods that will enable teeth (through defective formation of the dental enamel) to be used as biomarkers of adverse early life exposures and, potentially, as a clinical screening tool for subsequent health risk. Dr. Masterson led the efforts for the creation of the PANS Registry, a public registry collecting medical information on PANS patients and their families.

Jennifer Frankovich, MD, MS 
PANS Clinical Biorepository Director, PANS Research Program Director

  • Clinical Professor
  • Stanford Children's Health
  • Pediatric Rheumatology

Austism in PANS

Richard Frye, MD, PhD

  • Professor of Child Health, Neurology
  • Phoenix Children's Hospital
  • Dr. Richard Frye is a child neurologist with expertise in neurodevelopmental and neurometabolic disorders. He has conducted several clinical trials demonstrating the efficacy of safe and novel treatments that target underlying physiological abnormalities in children with Autism Spectrum Disorder. Dr. Frye is chief of neurodevelopmental disorders at Barrow Neurological Institute at Phoenix Children’s.

Sarkis Mazmanian, PhD

Microbiome-Based Therapeutics for Autism

  • Luis B. and Nelly Soux Professor of Microbiology, Caltech Investigator, Heritage Medical Research Institute
  • Cofounder and a board member of Axial Therapeutics.

Stewart Campbell, PhD

Microbiome based therapeautics 

  • CEO, Axial Therapeautics

Postdocs and Research Affiliates

Shamma Rahman, PhD

Monocyte Research

  • Postdoctoral Scholar
  • Stanford University School of Medicine
  • Pediatrics Human Gene Therapy (Mellins Lab)

Ayan Mondal, PhD

Blood Brain Barrier

  • Postdoctoral Scholar
  • Stanford University School of Medicine
  • Pediatrics Human Gene Therapy (Mellins Lab)

Tyler Prestwood, MD PhD

Influence of the immune system on psychiatric illness

  • Stanford University School of Medicine
  • Psychiatry (Utz Lab)

Xihui Yin, BS

Autoantibody Profiling in the Utz Lab

  • Research Associate
  • Stanford University School of Medicine
  • Immunology and Rheumatology (Utz Lab)