External PANS Basic Science and Research Collaborators

Jill Hollenbach, PhD, MPH

  • Associate Professor, Neurology
  • University of California, San Francisco
  • The Hollenbach Lab specializes in analysis of the extremely polymorphic human leukocyte antigen (HLA) and killer immunoglobulin-like receptor (KIR) immunogenetic systems. In addition to their critical role in transplantation, over 100 infectious, autoimmune and pharmacological disease phenotypes and cancers are associated with genetic variation of HLA and KIR, which also have functional interaction with one another. She is running analyses on a cohort of our patient specimens.

Omar Cornejo, PhD

  • Associate Professor in the School of Biological Sciences at Washington State University.
  • Washington State University
  • Dr. Cornejo is a population geneticist specializing in infectious diseases and human genetics. He is primarily interested in how microbes and pathogens have evolved and shaped each other's genomes.  Dr. Cornejo is a continual participant in our PANS basic science team and is lending his expertise to help pave the way for oral and gut microbiome projects.

Naresha Saligrama, PhD

  • Assistant Professor of Neurology
  • Washington University St.Louis
  • The Saligrama lab is dedicated to understanding the adaptive immune responses in health and neurological disorders. He began T cell work in PANS during his time as a postdoc in Dr. David Lewis's lab, and continues this research in his lab at Washington University, St Louis. 

Juliette Madan, MD, MS

  • Associate Professor, Pediatrics, Epidemiology, Quantitative Biomedical Data Science
  • Dartmouth
  • Dr. Madan joined the Dartmouth Children’s Center as its Clinical Research Director, expanding the microbiome research program to investigate the relationship between early microbiome development and health outcomes, including neurodevelopmental and neuropsychological outcomes (the gut-brain axis). Recent expansion of this work has included expansion of translational research as part of her Directorship of the Psycho-Immunology and Neurology Group at Dartmouth within Child Psychiatry.

Anne McHugh, MD

Behavioral Health Research in Patients with Arthritis

  • Former Stanford Postdoctural Medical Fellow
  • Dayton Children's Hospital
  • Dr. McHugh is a Pediatric Rheumatologist and began research on behavioral symptoms in rheumatology patients as a fellow on the NIH T-32 grant. She has continued her work post fellowship in her clinical practice as Dayton Children's in Dayton, Ohio. 

Christopher Pittenger, MD, PhD, FAPA, FANA

  • Professor of Psychiatry; Assistant Chair for Translational Research, Psychiatry; Director, Yale OCD Research Clinic; Director, Neuroscience Research Training Program, Yale Department of Psychiatry
  • Yale
  • Dr. Pittenger researches the basal ganglia (regulator of motor and behavioral function) and the consequences of its dysfunction in various diseases like obsessive-compulsive disorder, tics, and Tourette syndrome. He and his colleagues have discovered autoantibodies against neurons within the basal ganglia which alter the behavior of the brains neural network and is likely involved in driving PANS symptoms. His work has included specimens from our patient cohort.

Madeleine Cunningham, PhD

  • George Lynn Cross Research Professor
  • Oklahoma State University
  • Dr. Cunningham's laboratory has been highly focused on the investigation of molecular mimicry, autoimmunity and infection in inflammatory heart disease for the past 20 years. A second focus of the laboratory is on the study of autoimmunity and behavior which is manifest in diseases such as Sydenham's chorea following group A streptococcal infection. 

Erin Masterson, PhD, MPH

  • Epidemiologist
  • University of Washington, Seattle
  • Dr. Masterson's research is broadly focused on the developmental origins and social determinants of health. Specifically, she is developing methods that will enable teeth (through defective formation of the dental enamel) to be used as biomarkers of adverse early life exposures and, potentially, as a clinical screening tool for subsequent health risk. Dr. Masterson led the efforts for the creation of the PANS Registry, a public registry collecting medical information on PANS patients and their families.

Christopher Bartley, MD, PhD

  • Adjunct Instructor-HCOMP, Psychiatry
    UCSF Weill Institute for Neurosciences
  • University of California, San Francisco
  • Dr. Bartley is a physician-scientist who oversees the Immunopsychiatry Clinic in the Department of Psychiatry at University of California, San Francisco. In that clinic he provides consultations for patients with immune-related psychiatric symptoms. As a scientist, Dr. Bartley works closely with his neuroinflammatory colleagues in the Department of Neurology to discover new brain-targeting antibodies that may be relevant to psychiatric and/or neurologic syndromes. Dr. Bartley research utilizes CSF from our Stanford patient cohort.

Richard Frye, MD, PhD

  • Professor of Child Health, Neurology
  • Phoenix Children's Hospital
  • Dr. Richard Frye is a child neurologist with expertise in neurodevelopmental and neurometabolic disorders. He has conducted several clinical trials demonstrating the efficacy of safe and novel treatments that target underlying physiological abnormalities in children with Autism Spectrum Disorder. Dr. Frye is chief of neurodevelopmental disorders at Barrow Neurological Institute at Phoenix Children’s.