Welcome to the Owen Lab

The Owen lab studies how neuromodulation can shape the activity of targeted cell types and circuits to guide behavior. Our goal is to understand how specialized physiology, connectivity, and cell-signaling support the diverse functions of individual neuronal cell types. How can a deeper understanding of these features guide future therapeutic interventions for neurological diseases including Autism, Obsessive-Compulsive Disorder, and Parkinson’s Disease? To address these questions, we integrate a diverse set of experimental approaches, including human and mouse brain slice physiology, single-cell RNA sequencing, operant mouse behavior, in vivo physiology, imaging, and tool development.