Our laboratory uses the skin and other epithelia to answer unresolved questions in stem cell biology and regenerative medicine, cancer genetics and metastasis, and degenerative diseases. We aim to use our basic discoveries to develop novel cellular and molecular therapies for epithelial diseases and demonstrate their effectiveness in clinic. In the process, our goal is to train the brightest and most promising biomedical scientists using the newest stem cell, genomic, and bioinformatic approaches.