September 01 Sep 01
2023
Friday Fri

Meeting Details:

2:00PM-2:30PM - Refreshments

2:30PM-3:30PM – Seminar

Tung Auditorium, Biomedical Innovations Bldg – Room 1021

Host: Dr. Daibhid O Maoileidigh

Physics of the Auditory System

Dolores Bozovic, PhD, University of California Los Angeles

Hair cells of the auditory system constitute a remarkable biological sensor that exhibits nanometer-scale sensitivity of mechanical detection. Our experiments explore the active nonlinear processes behind the detection of very weak signals. We demonstrate the presence of chaos in the innate motility of active bundles, and explore both theoretically and experimentally its role in enhancing the sensitivity of detection. We further show that these cells utilize weakly chaotic dynamics to combine sensitive response with high temporal resolution. The presence of chaos in individual hair bundles also aids in the synchronization between coupled hair cells, and gives rise to new dynamical states. Finally, we explore the neural mechanisms that reduce and control the responsiveness of the cell. Specifically, we show that the efferent neurons serve as a gain control system, which can strongly affect the very compliance of the mechanosensory cells.

Speaker

Dolores Bozovic, PhD
Professor
Department of Physics and Astronomy
University of California Los Angeles

Location

Stanford University School of Medicine
240 Pasteur Dr. Rm 1021
Palo Alto, CA 94304
USA

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Stanford University School of Medicine

240 Pasteur Dr. Rm 1021
Palo Alto, CA 94304
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