Postoperative Pain Management in Rhinoplasty

The primary purpose of the study is to determine adequacy of postoperative pain control after nasal surgery in patients prescribed Acetaminophen (325mg) + Hydrocodone (5mg) compared to Acetaminophen(325mg) + Ibuprofen (200mg)for a period of 5 days after nasal surgery. To assess the degree of pain, the participants will score the intensity of their pain on a visual analog scale(VAS)of 0-100points (0- no pain and 100- most severe pain), preoperatively and postoperatively (to be documented before each dose) for the duration of the prescribed medications .

Additionally, the study will also seek to track:

1. The total number of pills each patients consume from the prescribed 5 day regimen.

2. Any associated side effects.

3. Additional pain medications prescribed in case of inadequate pain control, postoperatively.

Stanford is currently accepting patients for this trial.

Lead Sponsor:

Stanford University

Stanford Investigator(s):


  • Drug: Norco 5Mg-325Mg Tablet
  • Drug: Tylenol 325Mg Caplet
  • Drug: Ibuprofen 200 mg


Phase 2


Inclusion Criteria:

   - Minimum age of 18 years

   - Able to speak and understand english.

   - Undergoing rhinoplasty for cosmetic purposes

   - Undergoing rhinoplasty for treatment of nasal obstruction

Exclusion Criteria:

   - Less than 18 years of age

   - Cannot speak and understand english

   - Patients not undergoing nasal surgery.

   - Women will be excluded if they are either pregnant or lactating as this population
   does not undergo nasal surgery at our center.

   - Patients with any known allergies to the class of pain medications used in the study.

Ages Eligible for Study

18 Years - N/A

Genders Eligible for Study


Now accepting new patients

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Cherian K Kandathil, MD
Not Recruiting