The Keto-Med Trial - Contrasting Ketogenic and Mediterranean Diets in Individuals With Type 2 Diabetes and Prediabetes

We Want to Know...

The objective of this study was to compare two metabolically distinct diets, a well-formulated Ketogenic diet (WFKD) vs a Mediterranean Diet (Med-Plus), in order to examine the potential benefits, and unintended consequences, of going beyond a focus on maximally avoiding added sugars and refined grains, to also avoiding legumes, fruits, and whole grains.

Eligible Participants

Eligible participant are:

  • 18 years or older
  • Have type-2 diabetes or pre-diabetes

Study Design

If eligible, participants were asked to:

  • Eat both a Ketogenic (WFKD) and Mediterranean (Med-Plus) diet for 12 weeks each.
  • Attend 7 clinic visits over a 16-week period (30 minutes each).
  • Attend up to 14 classes with a registered dietitian.
  • Maintain dietary food records throughout the study.
  • Provide blood and stool samples, and complete questionnaires.
  • Wear a continuous glucose monitor (CGM) for 2 weeks at 6 time points throughout the study.


Upon completion, participants will receive the following free of charge:

  • Results of their blood analyses
  • A “map” of their microbiota composition

How to Participate

This study is now closed to enrollment.

If you have questions, please email