Williams Lab

For information on the Williams lab, please visit the Williams PanLab website.

Selected Center Papers

Hack LM, Zhang X, Heifets BD, Suppes T, van Roessel PJ, Yesavage JA, Gray NJ, Hilton R, Rodriguez CI, Deisseroth K, Knutson B, Williams LM. Ketamine’s acute effects on negative brain states are mediated through distinct dissociative states in humans. In Revision with Nature Communications

Rijsketic DR, Casey AB, Barbosa DAN, et al. UNRAVELing the synergistic effects of psilocybin and environment on brain-wide immediate early gene expression in mice. Preprint. bioRxiv. 2023;2023.02.19.528997. Published 2023 Feb 21. doi:10.1101/2023.02.19.528997 [PDF]

Hack LM, Warthen KG, Zhang X, Heifets BD, Suppes T, van Roessel PJ, Rodriguez CI, Knutson B, Williams LM. Acute Ketamine Modulated Functional Brain Coupling and Dissociative and Affective States in Human Subjects: Interim Analyses. bioRxiv. 2021 Sep 20. doi: 10.1101/2021.09.20.460992. [PDF]

White, T. Falling for Psychedelics. Stanford Magazine (2023) [PDF]

Abstracts

Zhang X*, Hack LM*, Warthen KG*, Heifets BD, Suppes T, van Roessel P, Rodriguez CI**, Knutson B**, Williams LM**. Acute Ketamine Modulated Functional Brain Coupling and Dissociative and Affective States in Human Subjects. Stanford University Wu Tsai Neurosciences Institute symposium. (2021) (*Equal first authors, **Equal senior authors.)

Hack LM, Zhang X, Brawer J, Gray N, Heifets B, Suppes T, van Roessel P, Rodriguez C, Knutson B, Williams LM. Deconstructing Ketamine-Induced Changes in Cortisol and Dissociative and Affective States in a Controlled Mechanistic Study. Biological Psychiatry, 91(9), S178-S179 (2022) [PDF]

Zhang X, Hack LM, Brawer J, Gray N, Heifets B, Suppes T, van Roessel P, Rodriguez C, Knutson B, Williams LM. Acute Ketamine Modulates Cognitive Control Network Activity during Cognitive Inhibition: Evidence from a Mechanistic Trial. Biological Psychiatry, 91(9), S225 (2022) [PDF]

Conferences

2023

Presentation at the Inaugural Bay Area Psychedelic Science Symposium, title: “The Doors of Precision: Personalizing psychedelics based on brain circuits and experiences”, Stanford, March 16.

Leanne Williams, PhD: The Doors of Precision: Personalizing psychedelics based on brain circuits and experiences

Boris Heifets, MD, PhD: Brain-wide neural correlates of set and setting for MDMA and psilocybin in mice

Karl Deisseroth, MD, PhD: Inner workings of channelrhodopsins and brains

2022

Precision Mental Health and Wellness Anniversary Symposium “The future of personalized neuroscience and mental health”, September 28.

Karl Deisseroth, MD, PhD, plenary: Translational neuroscience of drug-altered states

Boris Heifets, MD, PhD: Rapid acting mental health therapeutics