Rodriguez Lab

For information on the Rodriguez Lab, visit the Rodriguez Lab website.

Selected Center Papers

Hack LM, Zhang X, Heifets BD, Suppes T, van Roessel PJ, Yesavage JA, Gray NJ, Hilton R, Rodriguez CI, Deisseroth K, Knutson B, Williams LM. Ketamine’s acute effects on negative brain states are mediated through distinct dissociative states in humans. In Revision with Nature Communications

Hack LM, Warthen KG, Zhang X, Heifets BD, Suppes T, van Roessel PJ, Rodriguez CI, Knutson B, Williams LM. Acute Ketamine Modulated Functional Brain Coupling and Dissociative and Affective States in Human Subjects: Interim Analyses. bioRxiv. 2021 Sep 20. doi: 10.1101/2021.09.20.460992. [PDF]

Selected Lab Papers

Reiff, C., Richman, E., Nemeroff, C.B., Carpenter, L., Widge, A., Rodriguez, C.I., Kalin, N.H., McDonald, W.M. Psychedelics and Psychedelic-Assisted Therapy. American Journal of Psychiatry, 2020. May 01;177(5):391-410. PMID: 32098487. [PDF]
 
Hill, K.P., Gold, M.S., Nemeroff, C.B., McDonald, W.M., Grzenda, A., Widge, A.S., Rodriguez, C.I., Kraguljac, N.V., and Krystal, J.H. Risks and Benefits of Cannabis and Cannabinoids in Psychiatry. American Journal of Psychiatry, 2022. Feb; 179(2):98-109. PMID: 34875873. [PDF]
 
Kajs, B.L., van Roessel, P., Davis, G., Williams, L.M., Rodriguez, C.I. and Gunaydin, L.A. Valence Processing Alterations Associated with Compulsive Behavior in SAPAP3 Knockout Mice and Human OCD. Journal of Psychiatric Research, 2022 07; 151: 657-666. PMID: 35661523. [PDF]
 
Rodriguez, C.I., Chen, C., Glover, G., Jo, B., Spielman, D., Williams, L., Van Roessel, P., DeBattista, C., Flood, P., Ringold, A., Wintermark, M., Anderson, K., Linkovski, O., Lombardi, A., Millen, A., Pinto, A., Raila, H., Valentine, K., Filippou-Frye, M., Hawkins, J., McCarthy, E., Mukunda, P., Varias, A., Wilson, J., Wright, B. Efficacy of Ketamine in Unmedicated Adults With Obsessive-Compulsive Disorder: A Randomized Controlled Trial. Neuropsychopharmacology (2022) 47: 302-303. [PDF]
 
Davis, G., Minerva, A.R.., Lario, A., Rodriguez, C.I., Gunaydin, L.A. Ketamine increases activity of a fronto-striatal projection that regulates compulsive behavior. Nature Communications, 2021 10 15;12(1):6040. PMID: 34654803. PMCID: PMC8519915. [PDF, Figure 2, Figure 8]
 

Selected Center Abstracts

Hack LM, Zhang X, Brawer J, Gray N, Heifets B, Suppes T, van Roessel P, Rodriguez C, Knutson B, Williams LM. Deconstructing Ketamine-Induced Changes in Cortisol and Dissociative and Affective States in a Controlled Mechanistic Study. Biological Psychiatry, 91(9), S178-S179 (2022) [PDF]

Zhang X, Hack LM, Brawer J, Gray N, Heifets B, Suppes T, van Roessel P, Rodriguez C, Knutson B, Williams LM. Acute Ketamine Modulates Cognitive Control Network Activity during Cognitive Inhibition: Evidence from a Mechanistic Trial. Biological Psychiatry, 91(9), S225 (2022) [PDF]