Malenka Lab

For information on the Malenka lab, visit the STAAR lab website.

Selected Center Papers

Rijsketic DR, Casey AB, Barbosa DAN, et al. UNRAVELing the synergistic effects of psilocybin and environment on brain-wide immediate early gene expression in mice. Preprint. bioRxiv. 2023;2023.02.19.528997. Published 2023 Feb 21. doi:10.1101/2023.02.19.528997 [PDF]

Pomrenze MB, Cardozo Pinto DF, Neumann PA, Llorach P, Tucciarone JM, Morishita W, Eshel N, Heifets BD, Malenka RC. Modulation of 5-HT release by dynorphin mediates social deficits during opioid withdrawal. Neuron. 2022 Dec 21;110(24):4125-4143.e6. doi: 10.1016/j.neuron.2022.09.024. Epub 2022 Oct 5. PMID: 36202097; PMCID: PMC9789200. [Pubmed]

Christoffel DJ, Walsh JJ, Hoerbelt P, Heifets BD, Llorach P, Lopez RC, Ramakrishnan C, Deisseroth K, Malenka RC. Selective filtering of excitatory inputs to nucleus accumbens by dopamine and serotonin. Proc Natl Acad Sci U S A. 2021 Jun 15;118(24):e2106648118. doi: 10.1073/pnas.2106648118. PMID: 34103400; PMCID: PMC8214692. [PDF]
 

Heifets BD, Malenka RC. Better living through chemistry: MDMA's prosocial mechanism as a starting point for improved therapeutics. Neuropsychopharmacology. 2021 Jan;46(1):261. doi: 10.1038/s41386-020-00803-8. PMID: 32792684; PMCID: PMC7688942. [Pubmed]

Kim CK, Sanchez MI, Hoerbelt P, Fenno LE, Malenka RC, Deisseroth K, Ting AY. A Molecular Calcium Integrator Reveals a Striatal Cell Type Driving Aversion. Cell. 2020 Dec 23;183(7):2003-2019.e16. doi: 10.1016/j.cell.2020.11.015. Epub 2020 Dec 11. PMID: 33308478; PMCID: PMC9839359. [PDF]

Vesuna S, Kauvar IV, Richman E, Gore F, Oskotsky T, Sava-Segal C, Luo L, Malenka RC, Henderson JM, Nuyujukian P, Parvizi J, Deisseroth K. Deep posteromedial cortical rhythm in dissociation. Nature. 2020 Oct;586(7827):87-94. doi: 10.1038/s41586-020-2731-9. Epub 2020 Sep 16. PMID: 32939091; PMCID: PMC7553818. [PDF]

Steinberg EE, Gore F, Heifets BD, Taylor MD, Norville ZC, Beier KT, Földy C, Lerner TN, Luo L, Deisseroth K, Malenka RC. Amygdala-Midbrain Connections Modulate Appetitive and Aversive Learning. Neuron. 2020 Jun 17;106(6):1026-1043.e9. doi: 10.1016/j.neuron.2020.03.016. Epub 2020 Apr 14. PMID: 32294466. [Pubmed]

Heifets BD, Salgado JS, Taylor MD, Hoerbelt P, Cardozo Pinto DF, Steinberg EE, Walsh JJ, Sze JY, Malenka RC. Distinct neural mechanisms for the prosocial and rewarding properties of MDMA. Sci Transl Med. 2019 Dec 11;11(522):eaaw6435. doi: 10.1126/scitranslmed.aaw6435. PMID: 31826983; PMCID: PMC7123941. [PDF]

Beier KT, Kim CK, Hoerbelt P, Hung LW, Heifets BD, DeLoach KE, Mosca TJ, Neuner S, Deisseroth K, Luo L, Malenka RC. Rabies screen reveals GPe control of cocaine-triggered plasticity. Nature. 2017 Sep 21;549(7672):345-350. doi: 10.1038/nature23888. Epub 2017 Sep 13. PMID: 28902833; PMCID: PMC6069680. [PDF]

Humphreys K, Malenka RC, Knutson B, MacCoun RJ. Brains, environments, and policy responses to addiction. Science. 2017 Jun 23;356(6344):1237-1238. doi: 10.1126/science.aan0655. PMID: 28642399. [PDF]