Stem Cells

An active protein component of royal jelly helps honeybees create new queens. Stanford researchers have identified a similar protein in mammals, which keeps cultured embryonic stem cells pluripotent.

New research from Stanford shows that skeletal stem cells in mice assume a more primitive developmental state in response to extensive regeneration needs and environmental cues.

Identification of the human skeletal stem cell by Stanford scientists could pave the way for regenerative treatments for bone fractures, arthritis and joint injuries.

The discovery by Stanford scientists drills a peephole into the black box of cellular reprogramming and may lead to new ways to generate induced pluripotent stem cells in the laboratory.

Stanford researchers used genetic-editing tools and stem cell technology to uncover whether a genetic mutation linked to a heart rhythm disorder was benign or pathogenic.

Fresh or frozen human blood samples can be directly transformed into patient-specific neurons to study disorders such as schizophrenia and autism, Stanford researchers find.

Bertha Chen, MD, professor of obstetrics and gynecology, will receive nearly $6 million from the state stem cell agency to support research into the use of stem cells to treat urinary incontinence.

The California Institute for Regenerative Medicine awarded Stanford researcher Crystal Mackall a grant to study immune cells genetically modified to attack two proteins on leukemia and lymphoma cells.

A subset of liver cells with high levels of telomerase renews the organ during normal cell turnover and after injury, according to Stanford researchers. The cells may also give rise to liver cancer.

Young, resting neural stem cells have large protein clumps often associated with neurodegeneration. As stem cells age, the aggregates inhibit their ability to make new neurons, Stanford researchers say.

In a clinical trial, participants were given an antibody to CD117, a cell surface marker, in an effort to wipe out their defective blood stem cells without high-risk chemotherapy or radiation.