Stem Cells
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If the antibody treatment is eventually found to be viable in humans, it could increase the numbers of people who benefit from hematopoietic stem transplants, Stanford researchers said.
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Toward radiation-free stem cell transplants
Researchers at Stanford and the University of Tokyo may have cracked the code to doing stem cell transplants and gene therapy without radiation and chemotherapy.
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Possible ‘bubble boy’ disease therapy
In preclinical trials, Stanford scientists and their collaborators harnessed the gene-editing system CRISPR-Cas9 to replace the mutated gene underpinning the devastating immune disease.
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Gentler pre-transplant treatment with antibody
An antibody to a protein on blood-forming stem cells may allow bone marrow transplants without the need for chemotherapy and radiation, according to a Stanford study.
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Transplants without tissue-matching?
Researchers’ experimental approach for preparing mice for blood stem cell transplantation may one day make it possible in humans to safely transplant organs or cells from any donor to any recipient.
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What sea invertebrate reveals about us
A lowly sea creature may provide a way to understand our own blood-forming system, improve our immune function and find new immune-associated tools for biological discovery, Stanford researchers say.
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Bee-made protein keeps stem cells primed
An active protein component of royal jelly helps honeybees create new queens. Stanford researchers have identified a similar protein in mammals, which keeps cultured embryonic stem cells pluripotent.
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Adult stem cells channel early development
New research from Stanford shows that skeletal stem cells in mice assume a more primitive developmental state in response to extensive regeneration needs and environmental cues.
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Human skeletal stem cell identified
Identification of the human skeletal stem cell by Stanford scientists could pave the way for regenerative treatments for bone fractures, arthritis and joint injuries.
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New protein essential for making stem cells
The discovery by Stanford scientists drills a peephole into the black box of cellular reprogramming and may lead to new ways to generate induced pluripotent stem cells in the laboratory.
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Study solves mystery of genetic mutation
Stanford researchers used genetic-editing tools and stem cell technology to uncover whether a genetic mutation linked to a heart rhythm disorder was benign or pathogenic.
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Neurons quickly generated from blood
Fresh or frozen human blood samples can be directly transformed into patient-specific neurons to study disorders such as schizophrenia and autism, Stanford researchers find.
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