Genetics

  • Tiny circles of DNA harbor cancer-associated oncogenes and immunomodulatory genes promoting cancer development. They arise during transformation from pre-cancer to cancer, say Stanford Medicine-led team.

  • Myc-caused sugar changes protect cancers

    A novel Stanford School of Medicine partnership uncovers a direct link between a cancer-associated gene, Myc, and sugar patterns on cancer cell surfaces that tell immune cells to stand down.

  • African-American Alzheimer’s risk factor

    A genetic risk factor found virtually exclusively among people of at least partial African ancestry substantially boosts the risk of incurring Alzheimer’s disease — but only sometimes.

  • Telomere length crucial in muscular dystrophy

    Telomeres shorten in heart muscle cells from people with Duchenne muscular dystrophy. A Stanford Medicine study finds blocking this process improves the health of these cells grown in a dish.

  • Blood drop yields lots of data

    Using a new technique called multi-omic microsampling, Stanford Medicine researchers can measure thousands of protein, fat and metabolic molecules from a single drop of blood.

  • $18 million for transplant and gene-editing research

    The California Institute for Regenerative Medicine has funded Stanford Medicine projects to improve kidney transplantation and advance treatment for a rare genetic disease in children.

  • Gel treatment heals blistering wounds

    Researchers find that a gel tested in patients with a life-threatening blistering skin disease helps wounds heal. The gel — the first topical gene therapy — awaits FDA approval.

  • Possible new way to kill cancer cells

    After finding long, repetitive sequences in the genomes of seven kinds of cancer, researchers at Stanford Medicine and their colleagues developed a molecule that curbed their production.

  • Predicting immunity from vaccination

    A gene signature seen in antibody-producing cells in the blood of vaccinated study participants could expedite vaccine development.

  • Bioethicists support researchers

    In the five decades since the emergence of recombinant DNA technology, researchers at Stanford Medicine have benefited from the close involvement of bioethics experts.

  • Fish study rebuts anti-evolution argument

    A key developmental gene governs the number and length of spines in the stickleback, Stanford Medicine researchers find. The discovery supports the concept of progressive evolution in nature.

  • Step toward growing organs

    Researchers have shown initial viability of an embryo that contains both chimpanzee and macaque cells in a preliminary study that explores the feasibility of primate organ genesis.


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