Genetics
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Tiny circles of DNA harbor cancer-associated oncogenes and immunomodulatory genes promoting cancer development. They arise during transformation from pre-cancer to cancer, say Stanford Medicine-led team.
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Myc-caused sugar changes protect cancers
A novel Stanford School of Medicine partnership uncovers a direct link between a cancer-associated gene, Myc, and sugar patterns on cancer cell surfaces that tell immune cells to stand down.
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African-American Alzheimer’s risk factor
A genetic risk factor found virtually exclusively among people of at least partial African ancestry substantially boosts the risk of incurring Alzheimer’s disease — but only sometimes.
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Telomere length crucial in muscular dystrophy
Telomeres shorten in heart muscle cells from people with Duchenne muscular dystrophy. A Stanford Medicine study finds blocking this process improves the health of these cells grown in a dish.
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Blood drop yields lots of data
Using a new technique called multi-omic microsampling, Stanford Medicine researchers can measure thousands of protein, fat and metabolic molecules from a single drop of blood.
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$18 million for transplant and gene-editing research
The California Institute for Regenerative Medicine has funded Stanford Medicine projects to improve kidney transplantation and advance treatment for a rare genetic disease in children.
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Gel treatment heals blistering wounds
Researchers find that a gel tested in patients with a life-threatening blistering skin disease helps wounds heal. The gel — the first topical gene therapy — awaits FDA approval.
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Possible new way to kill cancer cells
After finding long, repetitive sequences in the genomes of seven kinds of cancer, researchers at Stanford Medicine and their colleagues developed a molecule that curbed their production.
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Predicting immunity from vaccination
A gene signature seen in antibody-producing cells in the blood of vaccinated study participants could expedite vaccine development.
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Bioethicists support researchers
In the five decades since the emergence of recombinant DNA technology, researchers at Stanford Medicine have benefited from the close involvement of bioethics experts.
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Fish study rebuts anti-evolution argument
A key developmental gene governs the number and length of spines in the stickleback, Stanford Medicine researchers find. The discovery supports the concept of progressive evolution in nature.
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Step toward growing organs
Researchers have shown initial viability of an embryo that contains both chimpanzee and macaque cells in a preliminary study that explores the feasibility of primate organ genesis.
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