Drug Development

Balls of intestinal cells from people with celiac disease faithfully model the disorder in a Stanford Medicine study. The lab-grown organoids revealed a new link between gluten and cell death.

In an early Stanford Medicine study, CAR-T cell therapy helps some with intractable lymphoma, but those who relapse have few options. Modifying the therapy’s molecular target improved response.

In a Stanford Medicine-led study, researchers combed through billions of compounds to find one that could enhance naloxone’s ability to fend off more potent opioids, with promising results in mice.

Experts at Stanford Medicine Children’s Health helped conduct clinical trials for the new therapy, which gives kids with X-linked adrenoleukodystrophy, or ALD, a functioning copy of the abnormal gene.

In an analysis of more than 2 million patient records, researchers discovered that people taking angiotensin receptor blockers for high blood pressure were less likely to develop epilepsy.

Stanford Medicine researchers devise a new artificial intelligence model, SyntheMol, which creates recipes for chemists to synthesize the drugs in the lab.

A Stanford Medicine study found that metformin, a commonly prescribed diabetes drug associated with moderate weight loss, stimulates production of lac-phe, a molecule abundant after exercise.

Stanford Medicine researchers clock the age of cells to find new therapy targets.

Hard-driving molecular virologist who used ‘advanced chemistry to unlock the tightly held secrets of viruses’ was also a hearty mountain man, scaling peaks in Alaska and Nepal.

A two-day event at the Stanford School of Medicine brought together investors, regulators, company executives and scientists to discuss the most productive ways for them to work together.

In a study led by Stanford Medicine researchers, a low-cost COVID-19 vaccine that does not require refrigeration provided immunity in rhesus monkeys for one year.