The Food and Drug Administration has approved a new and expensive medication for Alzheimer’s disease, but it’s not clear it helps. Researcher Kevin Schulman discusses what the government should consider before deciding to cover it.
Inflammatory-aging “clock” predicts health
Scientists at Stanford and the Buck Institute have found a way to predict an individual’s immunological decline as well as the likelihood of incurring age-associated diseases and becoming frail.
Study reveals immune driver of brain aging
Scientists have identified a key factor in mental aging and shown that it might be prevented or reversed by fixing a glitch in the immune system’s front-line soldiers.
Molecule restores strength in old mice
A single protein is a master regulator of mouse muscle function during aging, a Stanford study finds. Blocking this protein increased muscle strength and endurance in old animals. It may play a role in age-related muscle weakening in humans.
High-risk, high-reward grants for researchers
Annelise Barron, Peter Kim, Siddhartha Jaiswal and Keren Haroush will receive grants totaling $10 million to fund their investigations. The awards support risky efforts that could potentially have a big impact in the biomedical sciences.
How to better care for older adults at lower cost
Stanford Medicine researchers spotlight three approaches to late-life care that, if implemented broadly, could save tens of billions of dollars.
Alzheimer’s Disease Research Center grant
The Stanford-based center’s affiliated faculty and staff, aided by more than 400 volunteers, conduct research on Alzheimer’s and Parkinson’s diseases and related disorders.
Exercise rejuvenates stem cells of old mice
The researchers also identified a molecular pathway involved in turning back the clock on the cells. Drugs that could manipulate the pathway might be an effective substitute for exercise, they suggest.
Clues to how tiny fish ‘pauses’ life
Stanford scientists have identified molecular drivers that put the “pause” in “diapause,” a life stage of the African killifish that suspends its development as an embryo.
Transitional services after heart failure worth cost
A new study asserts that disease-management clinics, home visits by nurses and nurse case management should become the standard of care for elderly patients with heart failure after they are discharged from the hospital.
‘Ageotypes’ show how we age
Stanford scientists have identified specific biological pathways along which individuals age over time.
Alcohol, ‘Asian glow’ and Alzheimer’s
In the presence of alcohol, a defective version of the aldehyde dehydrogenase 2 gene in human cell cultures and mice leads to biochemical changes associated with Alzheimer’s disease.
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