Aging

  • The Food and Drug Administration has approved a new and expensive medication for Alzheimer’s disease, but it’s not clear it helps. Researcher Kevin Schulman discusses what the government should consider before deciding to cover it.

  • Inflammatory-aging “clock” predicts health

    Scientists at Stanford and the Buck Institute have found a way to predict an individual’s immunological decline as well as the likelihood of incurring age-associated diseases and becoming frail.

  • Study reveals immune driver of brain aging

    Scientists have identified a key factor in mental aging and shown that it might be prevented or reversed by fixing a glitch in the immune system’s front-line soldiers.

  • Molecule restores strength in old mice

    A single protein is a master regulator of mouse muscle function during aging, a Stanford study finds. Blocking this protein increased muscle strength and endurance in old animals. It may play a role in age-related muscle weakening in humans.

  • High-risk, high-reward grants for researchers

    Annelise Barron, Peter Kim, Siddhartha Jaiswal and Keren Haroush will receive grants totaling $10 million to fund their investigations. The awards support risky efforts that could potentially have a big impact in the biomedical sciences.

  • How to better care for older adults at lower cost

    Stanford Medicine researchers spotlight three approaches to late-life care that, if implemented broadly, could save tens of billions of dollars.

  • Alzheimer’s Disease Research Center grant

    The Stanford-based center’s affiliated faculty and staff, aided by more than 400 volunteers, conduct research on Alzheimer’s and Parkinson’s diseases and related disorders.

  • Exercise rejuvenates stem cells of old mice

    The researchers also identified a molecular pathway involved in turning back the clock on the cells. Drugs that could manipulate the pathway might be an effective substitute for exercise, they suggest.

  • Clues to how tiny fish ‘pauses’ life

    Stanford scientists have identified molecular drivers that put the “pause” in “diapause,” a life stage of the African killifish that suspends its development as an embryo.

  • Transitional services after heart failure worth cost

    A new study asserts that disease-management clinics, home visits by nurses and nurse case management should become the standard of care for elderly patients with heart failure after they are discharged from the hospital.

  • ‘Ageotypes’ show how we age

    Stanford scientists have identified specific biological pathways along which individuals age over time.

  • Alcohol, ‘Asian glow’ and Alzheimer’s

    In the presence of alcohol, a defective version of the aldehyde dehydrogenase 2 gene in human cell cultures and mice leads to biochemical changes associated with Alzheimer’s disease.


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