Aging & Geriatrics
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A single protein is a master regulator of mouse muscle function during aging, a Stanford study finds. Blocking this protein increased muscle strength and endurance in old animals. It may play a role in age-related muscle weakening in humans.
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High-risk, high-reward grants for researchers
Annelise Barron, Peter Kim, Siddhartha Jaiswal and Keren Haroush will receive grants totaling $10 million to fund their investigations. The awards support risky efforts that could potentially have a big impact in the biomedical sciences.
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Digital coach increases walking
A virtual adviser can help older adults become more physically active, a Stanford Medicine study reports.
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Method to regrow cartilage
In laboratory studies, Stanford School of Medicine researchers have found a way to regenerate the cartilage that eases movement between bones.
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How to better care for older adults at lower cost
Stanford Medicine researchers spotlight three approaches to late-life care that, if implemented broadly, could save tens of billions of dollars.
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Alzheimer’s Disease Research Center grant
The Stanford-based center’s affiliated faculty and staff, aided by more than 400 volunteers, conduct research on Alzheimer’s and Parkinson’s diseases and related disorders.
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Exercise rejuvenates stem cells of old mice
The researchers also identified a molecular pathway involved in turning back the clock on the cells. Drugs that could manipulate the pathway might be an effective substitute for exercise, they suggest.
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Old human cells rejuvenated
Old human cells can become more youthful by coaxing them to briefly express proteins used to make induced pluripotent cells, Stanford researchers and their colleagues have found. The finding may have implications for aging research.
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Clues to how tiny fish ‘pauses’ life
Stanford scientists have identified molecular drivers that put the “pause” in “diapause,” a life stage of the African killifish that suspends its development as an embryo.
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Transitional services after heart failure worth cost
A new study asserts that disease-management clinics, home visits by nurses and nurse case management should become the standard of care for elderly patients with heart failure after they are discharged from the hospital.
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‘Ageotypes’ show how we age
Stanford scientists have identified specific biological pathways along which individuals age over time.
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Alcohol, ‘Asian glow’ and Alzheimer’s
In the presence of alcohol, a defective version of the aldehyde dehydrogenase 2 gene in human cell cultures and mice leads to biochemical changes associated with Alzheimer’s disease.
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