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Medical Research August 25, 2022

Molecules, shmolecules. Why should you care?

By Krista Conger

We explore the most basic molecular elements of human biology in the lead story for the latests issue of Stanford Medicine magazine.

Writing the lead story for Stanford Medicine magazine is a privilege and a responsibility. It's basically a giant fishhook to entice readers to gobble the rest of the issue (which, I will say, is particularly stellar). My effort, "Human biology at its most basic," introduces our latest themed issue: "Molecules of Life." So my job was to convince all of you that — molecules are cool! Molecules are fun! Molecules are important!

To do so, I considered my bait carefully. A dash of Greek philosophy, a soupçon of chemistry and a pinch of history spiced up a story exploring what makes Stanford Medicine unique when it comes to the study of these tiny building blocks of life, and why it matters.

As senior associate dean for research, Ruth O'Hara, PhD, said in the article, "We are at an extremely important point in scientific history. Molecular medicine is a vast domain that spans from basic science research aimed at understanding the molecular basis of diseases, to identifying potential therapeutic targets, to preclinical and clinical trials of new drugs. Mining complex molecular data and overlaying them on clinical outcomes is critical for precision health and medicine, and Stanford Medicine excels at it. This is a special place."

Finding my favorite molecule

This issue is crammed with fantastic articles running the gamut of subjects from mucus to microscopy. Each explores the effects of molecules on human health and the ways we can study them ever more closely. As I write in the story: "These advances are further illuminating the secret lives of molecules — peering behind the curtain, under the sheets and in the closets — in ways that are expected to revolutionize how medicine is practiced."

One of my favorite stories, "My favorite molecule," asks a dozen Stanford researchers to pick — you guessed it — their favorite molecule and explain their choice. It's a great way to see how fondly scientists view the inanimate subjects of their studies, and a fascinating look into several amazing research projects.

Personally, I stumbled upon my new favorite molecule while doing the background research for my article. It's helium hydride — the first molecule that formed after the Big Bang created our universe. The heat and the power of the explosion slammed together an atom of helium and an atom of hydrogen, and they've been locked in an embrace for some 14 billion years. Think of it. The very first molecule! Amazing. I hope you'll find something to love in this issue as well.

Illustration by Jeffrey Decoster

About Stanford Medicine

Stanford Medicine is an integrated academic health system comprising the Stanford School of Medicine and adult and pediatric health care delivery systems. Together, they harness the full potential of biomedicine through collaborative research, education and clinical care for patients. For more information, please visit med.stanford.edu.

Krista-Conger

Science writer

Krista Conger

Senior science writer Krista Conger, PhD ’99, covers cancer, stem cells, dermatology, developmental biology, endocrinology, pathology, hematology, radiation oncology and LGBTQ+ issues for the office. She received her undergraduate degree in biochemistry at the University of California, Berkeley and her PhD in cancer biology from Stanford University. After completing the science writing program at UC Santa Cruz, she joined the Stanford Medicine Office of Communications in 2000. She enjoys distilling complicated scientific topics into engaging prose accessible to the layperson. Over the years, she has had chronicled nascent scientific discoveries from their inception to Food and Drug Administration approval and routine clinical use — documenting the wonder and long arc of medical research. Her writing has repeatedly been recognized with awards from the Counsel for the Advancement and Support of Education and the Association of American Medical Colleges. She is a member of the National Academy of Science Writers and a certified science editor through the Board of Editors in the Life Sciences. In her spare time, she enjoys textile arts, experimenting with new recipes and hiking in beautiful northwestern Montana, where she was raised and now lives.