The Rockefeller cell biologist and geneticist will give a talk at Stanford titled “Telomeres and the DNA damage response.”
February 20, 2019
Titia de Lange
Cell biologist and geneticist Titia de Lange, PhD, will give the 2019 Katharine D. McCormick Distinguished Lecture at 4 p.m. March 8 at the Li Ka Shing Center for Learning and Knowledge.
The title of her talk is “Telomeres and the DNA damage response.” The event is free and open to members of the Stanford community. A reception will follow. The deadline to register is March 7 at 7 p.m.
As director of the Anderson Center for Cancer Research at Rockefeller University, de Lange is also the Leon Hess Professor.
At Rockefeller, de Lange has focused on understanding how telomeres ensure the ends of chromosomes are not identified as damaged DNA. She identified the telomere binding proteins involved in protecting the ends of DNA and cloned the first human telomeric protein. Her subsequent work helped to identify the six-subunit shelterin complex and determined how shelterin represses the DNA damage response. She also investigates how loss of telomere protection drives genome instability in cancer.
The lectureship is named for Katharine Dexter McCormick, who left a large bequest to the Stanford School of Medicine. She earned a bachelor’s degree in biology from MIT in 1904. A suffragist and philanthropist, she is perhaps best known for funding research that led to the development of the first birth control pill.
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