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Cancer April 04, 2017

Researchers named Outstanding Investigators by the National Cancer Institute

By Krista Conger

Stanford cancer researchers Ronald Levy and Howard Chang have been named Outstanding Investigators by the National Cancer Institute. They were awarded grants of up to $7 million over six years to advance their studies.

Howard Chang Howard Chang

The National Cancer Institute has named professor of dermatology Howard Chang, MD, PhD, and professor of oncology Ronald Levy, MD, as recipients of the institute's Outstanding Investigator Awards for 2016.

The awards provide funding to investigators with outstanding records of productivity in cancer research. Recipients receive up to $600,000 each year for seven years to pursue or extend research projects of unusual potential. 

"This is a great honor and I am delighted to have this opportunity," said Chang. "We plan to use this award to investigate how a class of genes called long noncoding RNAs are involved in human cancers. We are particularly interested in how long noncoding RNAs may make each cell within the cancer different from one another - a property that makes cancer difficult to treat -  and also how specific chemical changes alter the meaning of long noncoding RNAs in cancer."

Ronald Levy Ronald Levy

Levy is investigating ways to train the immune system to attack and eradicate cancer cells.

"We are combining the discoveries that stimulate the immune system with new knowledge about the Achilles' heels of cancer cells," said Levy, who is the Robert K. and Helen K. Summy Professor in the School of Medicine. "Great strides have been made in these fields and we hope to bring them together to help patients."

"The NCI Outstanding Investigator Award addresses a problem that many cancer researchers experience: finding a balance between focusing on their science while ensuring that they will have funds to continue their research in the future," said Dinah Singer, PhD, director of NCI's Division of Cancer Biology. She added that providing seven years of uninterrupted funding gives investigators the opportunity to fully develop ambitious cancer research programs.

Chang is a core investigator at the Parker Institute for Cancer Immunotherapy at Stanford. He is also a member of Stanford's Child Health Research Institute, Cancer InstituteNeurosciences Institute, ChEM-H and Bio-X. Levy is a member of the Stanford Cancer Institute and Bio-X. 

About Stanford Medicine

Stanford Medicine is an integrated academic health system comprising the Stanford School of Medicine and adult and pediatric health care delivery systems. Together, they harness the full potential of biomedicine through collaborative research, education and clinical care for patients. For more information, please visit med.stanford.edu.

Krista-Conger

Science writer

Krista Conger

Senior science writer Krista Conger, PhD ’99, covers cancer, stem cells, dermatology, developmental biology, endocrinology, pathology, hematology, radiation oncology and LGBTQ+ issues for the office. She received her undergraduate degree in biochemistry at the University of California, Berkeley and her PhD in cancer biology from Stanford University. After completing the science writing program at UC Santa Cruz, she joined the Stanford Medicine Office of Communications in 2000. She enjoys distilling complicated scientific topics into engaging prose accessible to the layperson. Over the years, she has had chronicled nascent scientific discoveries from their inception to Food and Drug Administration approval and routine clinical use — documenting the wonder and long arc of medical research. Her writing has repeatedly been recognized with awards from the Counsel for the Advancement and Support of Education and the Association of American Medical Colleges. She is a member of the National Academy of Science Writers and a certified science editor through the Board of Editors in the Life Sciences. In her spare time, she enjoys textile arts, experimenting with new recipes and hiking in beautiful northwestern Montana, where she was raised and now lives.