Leonardino (Dino) Digma, MD
EDUCATION
Residency: Stanford Health Care
Internship: Stanford Health Care
MD: UC San Diego
Undergraduate: UC Berkeley
CLINICAL AND RESEARCH INTERESTS
- Neurodegenerative conditions
PUBLICATIONS
Digma LA, Madsen JR, Reas ET, Dale AM, Brewer JB, Banks SJ; Alzheimer’s Disease Neuroimaging Initiative. Tau and atrophy: domain-specific relationships with cognition. Alzheimers Res Ther. 2019 Jul 27;11(1):65. doi: 10.1186/s13195-019-0518-8. PMID: 31351484; PMCID: PMC6661099.
Digma LA, Madsen JR, Rissman RA, Jacobs DM, Brewer JB, Banks SJ; Alzheimer’s Disease Neuroimaging Initiative. Women can bear a bigger burden: ante- and post- mortem evidence for reserve in the face of tau. Brain Commun. 2020;2(1):fcaa025. doi: 10.1093/braincomms/fcaa025. Epub 2020 Apr 14. PMID: 32337508; PMCID: PMC7166251. Editor’s choice.
Spencer BE, Digma LA, Jennings RG, Brewer JB; Alzheimer's Disease Neuroimaging Initiative and the A4 Study Team. Gene- and age-informed screening for preclinical Alzheimer's disease trials. Alzheimers Dement. 2021 Mar;17(3):457-465. doi: 10.1002/alz.12207. Epub 2020 Nov 23. PMID: 33226723; PMCID: PMC8906231.
Banks SJ, Andrews MJ, Digma L, Madsen J, Reas ET, Caldwell JZK, McEvoy LK, Fan CC, Dale AM, Brewer JB; Alzheimer's Disease Neuroimaging Initiative. Sex differences in Alzheimer's disease: do differences in tau explain the verbal memory gap? Neurobiol Aging. 2021 Nov;107:70-77. doi: 10.1016/j.neurobiolaging.2021.05.013. Epub 2021 Jun 4. PMID: 34399127; PMCID: PMC8963683.
Digma LA, Feng CH, Conlin CC, Rodríguez-Soto AE, Zhong AY, Hussain TS, Lui AJ, Batra K, Simon AB, Karunamuni R, Kuperman J, Rakow-Penner R, Hahn ME, Dale AM, Seibert TM. Correcting B0 inhomogeneity-induced distortions in whole-body diffusion MRI of bone. Sci Rep. 2022 Jan 7;12(1):265. doi: 10.1038/s41598-021-04467-2. PMID: 34997164; PMCID: PMC8741963.
Zhong AY, Digma LA, Hussain T, Feng CH, Conlin CC, Tye K, Lui AJ, Andreassen MMS, Rodríguez-Soto AE, Karunamuni R, Kuperman J, Kane CJ, Rakow-Penner R, Hahn ME, Dale AM, Seibert TM. Automated Patient-level Prostate Cancer Detection with Quantitative Diffusion Magnetic Resonance Imaging. Eur Urol Open Sci. 2022 Dec 15;47:20-28. doi: 10.1016/j.euros.2022.11.009. PMID: 36601040; PMCID: PMC9806706.
Conlin CC, Feng CH, Digma LA, Rodríguez-Soto AE, Kuperman JM, Rakow-Penner R, Karow DS, White NS, Seibert TM, Hahn ME, Dale AM. A Multicompartmental Diffusion Model for Improved Assessment of Whole-Body Diffusion-weighted Imaging Data and Evaluation of Prostate Cancer Bone Metastases. Radiol Imaging Cancer. 2023 Jan;5(1):e210115. doi: 10.1148/rycan.210115. PMID: 36705559; PMCID: PMC9896230.
Digma LA, Litvan I, Del Ser T, Bayram E. Sex differences for cognitive decline in progressive supranuclear palsy. Parkinsonism Relat Disord. 2023 Jul;112:105454. doi: 10.1016/j.parkreldis.2023.105454. Epub 2023 Jun 2. PMID: 37301014; PMCID: PMC10911684.
Lui AJ, Kallis K, Zhong AY, Hussain TS, Conlin C, Digma LA, Phan N, Mathews IT, Do DD, Domingo MR, Karunamuni R, Kuperman J, Dale AM, Shabaik A, Rakow- Penner R, Hahn ME, Seibert TM. ReIGNITE Radiation Therapy Boost: A Prospective, International Study of Radiation Oncologists' Accuracy in Contouring Prostate Tumors for Focal Radiation Therapy Boost on Conventional Magnetic Resonance Imaging Alone or With Assistance of Restriction Spectrum Imaging. Int J Radiat Oncol Biol Phys. 2023 Dec 1;117(5):1145-1152. doi: 10.1016/j.ijrobp.2023.07.004. Epub 2023 Jul 14. PMID: 37453559.
Digma LA, Winer JR, Greicius MD. Substantial Doubt Remains about the Efficacy of Anti-Amyloid Antibodies. J Alzheimers Dis. 2024;97(2):567-572. doi: 10.3233/JAD-231198. PMID: 38250779.
HONORS AND AWARDS
2023 AAIC Clinical Trials Advancement PIA Best Student Poster
2021 ISMRM Annual Conference Trainee Educational Stipend
2020 National Institute on Aging Medical Student Training in Aging Research Grant
2018 Alzheimer’s Association International Conference Travel Award
2017 American Neurological Association Travel Award
2016 Molecular and Cellular Biology Departmental Honors
2015 UC Berkeley Summer Undergraduate Research Fellowship