David Hartmann, MD, PhD


  • New College of Florida, BA
  • Medical University of South Carolina, MD PhD



  • Cerebral blood flow
  • Platelets
  • Interictal spikes



Pericyte structure and distribution in the cerebral cortex revealed by high-resolution imaging of transgenic mice. DA Hartmann, RG Underly, RI Grant, AN Watson, V Lindner, AY Shih. Neurophotonics 2 (4), 041402

Pericytes as inducers of rapid, matrix metalloproteinase-9-dependent capillary damage during ischemia RG Underly, M Levy, DA Hartmann, RI Grant, AN Watson, AY Shih. Journal of Neuroscience 37 (1), 129-140

Organizational hierarchy and structural diversity of microvascular pericytes in adult mouse cortex RI Grant, DA Hartmann, RG Underly, AA Berthiaume, NR Bhat, AY Shih. Journal of Cerebral Blood Flow & Metabolism 39 (3), 411-425

Dynamic Remodeling of Pericytes In Vivo Maintains Capillary Coverage in the Adult Mouse Brain AA Berthiaume, RI Grant, KP McDowell, RG Underly, DA Hartmann,Cell reports 22 (1), 8-16

Functional deficits induced by cortical microinfarcts PM Summers, DA Hartmann, ES Hui, X Nie, RL Deardorff, ET McKinnon, ... Journal of Cerebral Blood Flow & Metabolism 37 (11), 3599-3614

Pericyte structural remodeling in cerebrovascular health and homeostasis AA Berthiaume, DA Hartmann, MW Majesky, NR Bhat, AY Shih. Frontiers in aging neuroscience 10, 210

A murine toolbox for imaging the neurovascular unit DA Hartmann, RG Underly, AN Watson, AY Shih. Microcirculation 22 (3), 168-182

Brain capillary pericytes exert a substantial but slow influence on blood flow DA Hartmann, AA Berthiaume, RI Grant, SA Harrill, T Koski, T Tieu, ... Nature Neuroscience, 1-13

Does pathology of small venules contribute to cerebral microinfarcts and dementia? DA Hartmann, HI Hyacinth, FF Liao, AY Shih. Journal of neurochemistry 144 (5), 517-526

Rodent Models of Cerebral Microinfarct and Microhemorrhage AY Shih, HI Hyacinth, DA Hartmann, SJ van Veluw. Stroke 49 (3), 803-810

Multiple approaches to investigate the transport and activity-dependent release of BDNF and their application in neurogenetic disorders D Hartmann, J Drummond, E Handberg, S Ewell, L Pozzo-Miller. Neural plasticity 2012

Mild pericyte deficiency is associated with aberrant brain microvascular flow in aged PDGFRβ+/− mice AN Watson, AA Berthiaume, AV Faino, KP McDowell, NR Bhat, ...Journal of Cerebral Blood Flow & Metabolism 40 (12), 2387-2400

VasoMetrics: unbiased spatiotemporal analysis of microvascular diameter in multi-photon imaging applications KP McDowell, AA Berthiaume, T Tieu, DA Hartmann, AY Shih. Quantitative Imaging in Medicine and Surgery 11 (3), 969

Clinical Problem Solving: An Older Woman With Weakness from Head to Toe. DA Hartmann, M Bock, V Douglas, J Gerdts, B Ramani, M Shah. The Neurohospitalist, 19418744211005321

Precise, 3-D optogenetic control of the diameter of single arterioles. PJ O’Herron, DA Hartmann, K Xie, P Kara, AY Shih. bioRxiv


  • Distinguished Graduate Award 2020 – Medical University of South Carolina
  • AAN Futures in Neurological Research Scholar 2019
  • 1st place Lasker Essay contest 2018
  • Gold Humanism Honor Society
  • Alpha Omega Alpha
  • NRSA F30



Playing basketball, hiking with my wife, making music, writing