Latest information on COVID-19

Publications

            

            

            

Clinical/Translational Research

2020

Yan, Carol H, Aakanksha Rathor, Kaelyn Krook, Yifei Ma, Melissa R Rotella, Robert L Dodd, Peter H Hwang, et al. “Effect of Omega-3 Supplementation in Patients With Smell Dysfunction Following Endoscopic Sellar and Parasellar Tumor Resection: A Multicenter Prospective Randomized Controlled Trial.” Neurosurgery, January 17, 2020, nyz559. https://doi.org/10.1093/neuros/nyz559.

Chang, Michael T., Davood K. Hosseini, Sun Hee Song, Jayakar V. Nayak, Zara M. Patel, Jennifer Y. Lee, and Peter H. Hwang. “The Effect of Endoscopic Sinus Surgery on Eustachian Tube Dysfunction Symptoms.” Otolaryngology–Head and Neck Surgery, April 28, 2020, 019459982091739. https://doi.org/10.1177/0194599820917396.

Patel, Zara M, Juan Fernandez-Miranda, Peter H Hwang, Jayakar V Nayak, Robert Dodd, Hamed Sajjadi, and Robert K Jackler. “Letter: Precautions for Endoscopic Transnasal Skull Base Surgery During the COVID-19 Pandemic.” Neurosurgery 87, no. 1 (July 1, 2020): E66–67. https://doi.org/10.1093/neuros/nyaa125.

Chang, Michael T., Kawinyarat Jitaroon, Teresa Nguyen, Carol H. Yan, Jonathan B. Overdevest, Jayakar V. Nayak, Peter H. Hwang, and Zara M. Patel. “Hemodynamic Changes in Patients Undergoing Office‐based Sinus Procedures under Local Anesthesia.” International Forum of Allergy & Rhinology 10, no. 1 (2020): 114–20. https://doi.org/10.1002/alr.22460.

Rahman, Arifeen S., Peter H. Hwang, Rahul Alapati, Yan Lin, Jayakar V. Nayak, Zara M. Patel, and Carol H. Yan. “Indications and Outcomes for Patients With Limited Symptoms Undergoing Endoscopic Sinus Surgery.” American Journal of Rhinology & Allergy 34, no. 4 (2020): 502–7. https://doi.org/10.1177/1945892420912159.

Tangbumrungtham, Navarat, Peter H. Hwang, Ximena Maul, Nicole A. Borchard, Sachi S. Dholakia, Zara M. Patel, Jayakar V. Nayak, and Garret Choby. “The Effect of Topical Epinephrine 1:1000 with and without Infiltration of 1% Lidocaine with Epinephrine 1:100,000 on Endoscopic Surgical Field Visualization: A Double‐blind Randomized Controlled Study.” International Forum of Allergy & Rhinology 10, no. 2 (2020): 147–52. https://doi.org/10.1002/alr.22468.

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2019

Walgama, Evan S., Andrew Thamboo, Navarat Tangbumrungtham, Noel Ayoub, Zara M. Patel, and Jayakar V. Nayak. “The Horizon Sign and Frontal Bar: Two Topographic Landmarks to Confirm Endoscopic Frontal Sinusotomy:” Otolaryngology–Head and Neck Surgery, January 29, 2019. https://doi.org/10.1177/0194599818825472.

Maul, Ximena A., Nicole A. Borchard, Peter H. Hwang, and Jayakar V. Nayak. “Microcurrent Technology for Rapid Relief of Sinus Pain: A Randomized, Placebo‐controlled, Double‐blinded Clinical Trial.” International Forum of Allergy & Rhinology 9, no. 4 (2019): 352–56. https://doi.org/10.1002/alr.22280.

Yan, Carol H., Charles C. L. Tong, Mrudula Penta, Vishal S. Patel, James N. Palmer, Nithin D. Adappa, Jayakar V. Nayak, Peter H. Hwang, and Zara M. Patel. “Imaging Predictors for Malignant Transformation of Inverted Papilloma.” The Laryngoscope 129, no. 4 (2019): 777–82. https://doi.org/10.1002/lary.27582.

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2018

Borchard, Nicole A., and Jayakar V. Nayak. “Orbital Apex Syndrome.” New England Journal of Medicine 378, no. 17 (April 26, 2018): e23. https://doi.org/10.1056/NEJMicm1703770.

Ayoub, Noel, Wirach Chitsuthipakorn, Jayakar V. Nayak, Zara M. Patel, and Peter H. Hwang. “Nose Blowing after Endoscopic Sinus Surgery Does Not Adversely Affect Outcomes.” The Laryngoscope 128, no. 6 (2018): 1268–73. https://doi.org/10.1002/lary.26907.

Beswick, Daniel M., Reza Vaezeafshar, Yifei Ma, Peter H. Hwang, Jayakar V. Nayak, and Zara M. Patel. “Risk Stratification for Postoperative Venous Thromboembolism after Endoscopic Sinus Surgery.” Otolaryngology–Head and Neck Surgery 158, no. 4 (2018): 767–73. https://doi.org/10.1177/0194599818755340.

Choby, Garret, and Jayakar V. Nayak. “The ‘Cross-Court Draf IIb’ Procedure for Advanced Nasal Septum or Frontal Sinus Pathology and Nasal Septum Pathology: Crosscourt Draf IIb.” The Laryngoscope 128, no. 7 (2018): 1527–30. https://doi.org/10.1002/lary.27016.

Nayak, Jayakar V., Aakanksha Rathor, Jessica W. Grayson, Dawn T. Bravo, Nathalia Velasquez, Julia Noel, Daniel M. Beswick, et al. “Porcine Small Intestine Submucosal Grafts Improve Remucosalization and Progenitor Cell Recruitment to Sites of Upper Airway Tissue Remodeling: Upper Airway Wound Healing through Donor Site Grafting.” International Forum of Allergy & Rhinology 8, no. 10 (2018): 1162–68. https://doi.org/10.1002/alr.22156.

Patel, Vishal S., Garret Choby, Liang-Chun Shih, Zara M. Patel, Jayakar V. Nayak, and Peter H. Hwang. “Equivalence in Outcomes between Draf 2B vs Draf 3 Frontal Sinusotomy for Refractory Chronic Frontal Rhinosinusitis: Draf 2B vs Draf 3 Outcomes.” International Forum of Allergy & Rhinology 8, no. 1 (2018): 25–31. https://doi.org/10.1002/alr.22032.

Tangbumrungtham, Navarat, Vishal S. Patel, Andrew Thamboo, Zara M. Patel, Jayakar V. Nayak, Yifei Ma, Garret Choby, and Peter H. Hwang. “The Prevalence of Eustachian Tube Dysfunction Symptoms in Patients with Chronic Rhinosinusitis: Eustachian Tube Dysfunction in CRS.” International Forum of Allergy & Rhinology 8, no. 5 (2018): 620–23. https://doi.org/10.1002/alr.22056.

Thamboo, Andrew, Aakanksha Rathor, Nicole A. Borchard, Jayakar V. Nayak, Peter H. Hwang, and Zara M. Patel. “Precision Medicine: Why Surgeons Deviate from ‘Appropriateness Criteria’ in the Management of Chronic Rhinosinusitis and Effects on Outcomes: Surgical Decision Making for CRS.” International Forum of Allergy & Rhinology 8, no. 12 (2018): 1389–94. https://doi.org/10.1002/alr.22184.

Yan, Carol H., Navarat Tangbumrungtham, Ximena A. Maul, Yifei Ma, Jayakar V. Nayak, Peter H. Hwang, and Zara M. Patel. “Comparison of Outcomes Following Culture-Directed vs Non-Culture-Directed Antibiotics in Treatment of Acute Exacerbations of Chronic Rhinosinusitis: Utility of Routine Culture in Sinusitis Treatment.” International Forum of Allergy & Rhinology 8, no. 9 (2018): 1028–33. https://doi.org/10.1002/alr.22147.

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2017

Omura, Kazuhiro, Daiya Asaka, Jayakar V. Nayak, and Yasuhiro Tanaka. “Transseptal Access with Crossing Multiple Incisions for Improved Pedicle Control and Septum Preservation: ‘How I Do It’:” American Journal of Rhinology & Allergy, March 1, 2017. https://doi.org/10.2500/ajra.2017.31.4416.

Abuzeid, Waleed M., Asa Z. Peterson, Aakanksha Rathor, Jordan C. Xu, Nathalia Velasquez, Ali R. Rashan, Andrew Thamboo, and Jayakar V. Nayak. “Enhanced Irrigant Delivery to the Ethmoid Sinuses Directly Following Ethmoid Punch Sinusotomy.” Annals of Otology, Rhinology & Laryngology 126, no. 12 (2017): 804–12. https://doi.org/10.1177/0003489417737323.

Ayoub, Noel, Andrew Thamboo, Al-Rahim Habib, Jayakar V. Nayak, and Peter H. Hwang. “Determinants and Outcomes of Upfront Surgery versus Medical Therapy for Chronic Rhinosinusitis in Cystic Fibrosis: Chronic Rhinosinusitis in Cystic Fibrosis.” International Forum of Allergy & Rhinology 7, no. 5 (2017): 450–58. https://doi.org/10.1002/alr.21912.

Ayoub, Noel, Evan Walgama, Andrew Thamboo, Jayakar V. Nayak, and Peter H. Hwang. “Efficacy of Endoscopic Sinus Surgery for Chronic Rhinosinusitis Following Primary Radiotherapy and Concurrent Chemotherapy for Nasopharyngeal Carcinoma: CRS Following Radiation Therapy for NPC.” International Forum of Allergy & Rhinology 7, no. 11 (2017): 1045–51. https://doi.org/10.1002/alr.22002.

Edward, Justin A., Alkis J. Psaltis, Ryan A. Williams, Gregory W. Charville, Robert L. Dodd, and Jayakar V. Nayak. “Endoscopic Resection of Skull Base Teratoma in Klippel-Feil Syndrome through Use of Combined Ultrasonic and Bipolar Diathermy Platforms.” Case Reports in Otolaryngology 2017 (2017): 1–7. https://doi.org/10.1155/2017/6384586.

Paknezhad, Hassan, Nicole A. Borchard, Greg W. Charville, Noel F. Ayoub, Garret W. Choby, Andrew Thamboo, and Jayakar V. Nayak. “Evidence for a ‘Preinvasive’ Variant of Fungal Sinusitis: Tissue Invasion without Angioinvasion.” World Journal of Otorhinolaryngology - Head and Neck Surgery 3, no. 1 (2017): 37–43. https://doi.org/10.1016/j.wjorl.2017.01.003.

Patel, Zara M., Andrew Thamboo, Luke Rudmik, Jayakar V. Nayak, Timothy L. Smith, and Peter H. Hwang. “Surgical Therapy vs Continued Medical Therapy for Medically Refractory Chronic Rhinosinusitis: A Systematic Review and Meta-Analysis: Surgery vs Medical Therapy for Refractory CRS.” International Forum of Allergy & Rhinology 7, no. 2 (2017): 119–27. https://doi.org/10.1002/alr.21872.

Patel, Vishal S., Andrew Thamboo, Jennifer Quon, Jayakar V. Nayak, Peter H. Hwang, Michael Edwards, and Zara M. Patel. “Outcomes After Endoscopic Endonasal Resection of Craniopharyngiomas in the Pediatric Population.” World Neurosurgery 108 (2017): 6–14. https://doi.org/10.1016/j.wneu.2017.08.058.

Vaezeafshar, Reza, Alkis J. Psaltis, Vidya K. Rao, David Zarabanda, Zara M. Patel, and Jayakar V. Nayak. “Barosinusitis: Comprehensive Review and Proposed New Classification System.” Allergy & Rhinology 8, no. 3 (2017): ar.2017.8.0221. https://doi.org/10.2500/ar.2017.8.0221.

Velasquez, Nathalia, Andrew Thamboo, Waleed M. Abuzeid, and Jayakar V. Nayak. “Safe Treatment of Ethmoid Sinusitis Utilizing Minimally Invasive Ethmoid Punch Sinusotomy in Chronic Rhinosinusitis without Polyposis Patients: Minimally Invasive Ethmoid Punch Sinusotomy.” The Laryngoscope 127, no. 6 (2017): 1268–75. https://doi.org/10.1002/lary.26493.

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2016

Noel, Julia E., Neville W. Teo, Vasu Divi, and Jayakar V. Nayak. “Use of Pedicled Nasoseptal Flap for Pathologic Oroantral Fistula Closure.” Journal of Oral and Maxillofacial Surgery 74, no. 4 (2016): 704.e1-704.e6. https://doi.org/10.1016/j.joms.2015.11.010.

Orlandi, Richard R., Todd T. Kingdom, Peter H. Hwang, Timothy L. Smith, Jeremiah A. Alt, Fuad M. Baroody, Pete S. Batra, et al. “International Consensus Statement on Allergy and Rhinology: Rhinosinusitis: International Consensus on Rhinosinusitis.” International Forum of Allergy & Rhinology 6, no. S1 (2016): S22–209. https://doi.org/10.1002/alr.21695.

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2015

Mohammadi, Fatemeh, Ali Rashan, Alkis Psaltis, Agnieszka Janisewicz, Peter Li, Tarek El-Sawy, and Jayakar V. Nayak. “Intraocular Pressure Changes in Emergent Surgical Decompression of Orbital Compartment Syndrome.” JAMA Otolaryngology–Head & Neck Surgery 141, no. 6 (June 1, 2015): 562. https://doi.org/10.1001/jamaoto.2015.0524.

Costa, Milena L., Alkis J. Psaltis, Jayakar V. Nayak, and Peter H. Hwang. “Long-Term Outcomes of Endoscopic Maxillary Mega-Antrostomy for Refractory Chronic Maxillary Sinusitis: Outcomes of Maxillary Mega-Antrostomy.” International Forum of Allergy & Rhinology 5, no. 1 (2015): 60–65. https://doi.org/10.1002/alr.21407.

Costa, Milena L., Alkis J. Psaltis, Jayakar V. Nayak, and Peter H. Hwang. “Medical Therapy vs Surgery for Recurrent Acute Rhinosinusitis: Recurrent Acute Rhinosinusitis.” International Forum of Allergy & Rhinology 5, no. 8 (2015): 667–73. https://doi.org/10.1002/alr.21533.

Huang, Zhenxiao, Amal Hajjij, Gang Li, Jayakar V. Nayak, Bing Zhou, and Peter H. Hwang. “Clinical Predictors of Neo-Osteogenesis in Patients with Chronic Rhinosinusitis: Clinical Predictors of Neo-Osteogenesis in CRS.” International Forum of Allergy & Rhinology 5, no. 4 (2015): 303–9. https://doi.org/10.1002/alr.21485.

Saedi, Babak, Ali R. Rashan, Michael Lipan, Jayakar V. Nayak, and Sam P. Most. “Consistent Ipsilateral Development of the Posterior Extension of the Quadrangular Cartilage and Bony Spur Formation in Nasal Septal Deviation.” Otolaryngology–Head and Neck Surgery 152, no. 3 (2015): 444–48. https://doi.org/10.1177/0194599814564549.

Soudry, Ethan, Alkis J. Psaltis, Kun H. Lee, Reza Vaezafshar, Jayakar V. Nayak, and Peter H. Hwang. “Complications Associated with the Pedicled Nasoseptal Flap for Skull Base Reconstruction: Nasoseptal Flap Complications.” The Laryngoscope 125, no. 1 (2015): 80–85. https://doi.org/10.1002/lary.24863.

Suh, Jeffrey D., Vijay R. Ramakrishnan, Christopher F. Thompson, Bradford A. Woodworth, Nithin D. Adappa, Jayakar Nayak, John M. Lee, Jivianne T. Lee, Alexander G. Chiu, and James N. Palmer. “Inverted Papilloma of the Sphenoid Sinus: Risk Factors for Disease Recurrence: Inverted Papilloma of the Sphenoid Sinus.” The Laryngoscope 125, no. 3 (2015): 544–48. https://doi.org/10.1002/lary.24929.

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2014

Santa Maria, Peter, Waleed Abuzeid, Jayakar Nayak, Steven Chang, and Nikolas Blevins. “A Case of Stereotactic Radiation in Skull Base Solitary Fibrous Tumor: More Harm Than Good?” Journal of Neurological Surgery Reports 75, no. 02 (August 11, 2014): e214–16. https://doi.org/10.1055/s-0034-1387196.

Ali, Mohammad Javed, Jayakar V. Nayak, Reza Vaezeafshar, Gang Li, and Alkis James Psaltis. “Anatomic Relationship of Nasolacrimal Duct and Major Lateral Wall Landmarks: Cadaveric Study with Surgical Implications: Endoscopic Landmarks of the Nasolacrimal Duct.” International Forum of Allergy & Rhinology 4, no. 8 (2014): 684–88. https://doi.org/10.1002/alr.21345.

Cho, Kyu-Sup, Ethan Soudry, Alkis J. Psaltis, Kari C. Nadeau, Sean A. McGhee, Jayakar V. Nayak, and Peter H. Hwang. “Long-Term Sinonasal Outcomes of Aspirin Desensitization in Aspirin Exacerbated Respiratory Disease.” Otolaryngology–Head and Neck Surgery 151, no. 4 (2014): 575–81. https://doi.org/10.1177/0194599814545750.

Choudhri, Omar, Stefan A. Mindea, Abdullah Feroze, Ethan Soudry, Steven D. Chang, and Jayakar V. Nayak. “Experience with Intraoperative Navigation and Imaging during Endoscopic Transnasal Spinal Approaches to the Foramen Magnum and Odontoid.” Neurosurgical Focus 36, no. 3 (2014): E4. https://doi.org/10.3171/2014.1.FOCUS13533.

Kumar, Anisha R., Jayakar V. Nayak, Agnieszka M. Janisiewicz, Gordon Li, and John S. Oghalai. “The Combined Subtemporal-Transfacial Approach for the Resection of Juvenile Nasopharyngeal Angiofibromas with Intracranial Extension:” Otology & Neurotology, 2014, 1. https://doi.org/10.1097/MAO.0000000000000498.

Soudry, Ethan, Paul K. Mohabir, Amar Miglani, Justin Chen, Jayakar V. Nayak, and Peter H. Hwang. “Outpatient Endoscopic Sinus Surgery in Cystic Fibrosis Patients: Predictive Factors for Admission: Outpatient Sinus Surgery and Cystic Fibrosis.” International Forum of Allergy & Rhinology 4, no. 5 (2014): 416–21. https://doi.org/10.1002/alr.21285.

Soudry, Ethan, Justin H. Turner, Jayakar V. Nayak, and Peter H. Hwang. “Endoscopic Reconstruction of Surgically Created Skull Base Defects: A Systematic Review.” Otolaryngology–Head and Neck Surgery 150, no. 5 (2014): 730–38. https://doi.org/10.1177/0194599814520685.

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2013

Turner, Justin H., Ethan Soudry, Jayakar V. Nayak, and Peter H. Hwang. “Survival Outcomes in Acute Invasive Fungal Sinusitis: A Systematic Review and Quantitative Synthesis of Published Evidence: Survival Outcomes in Invasive Fungal Sinusitis.” The Laryngoscope 123, no. 5 (2013): 1112–18. https://doi.org/10.1002/lary.23912.

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2012

Patel, Zara M., Peter H. Hwang, Ary Chernomorsky, Dawn T. Bravo, Bryan L. Nguyen, Klementina Nesterova, and Jayakar V. Nayak. “Low-Frequency Pulsed Ultrasound in the Nasal Cavity and Paranasal Sinuses: A Feasibility and Distribution Study.” International Forum of Allergy & Rhinology 2, no. 4 (2012): 303–8. https://doi.org/10.1002/alr.21039.

Ramakrishnan, Vijay R., Todd T. Kingdom, Jayakar V. Nayak, Peter H. Hwang, and Richard R. Orlandi. “Nationwide Incidence of Major Complications in Endoscopic Sinus Surgery.” International Forum of Allergy & Rhinology 2, no. 1 (2012): 34–39. https://doi.org/10.1002/alr.20101.

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2010

Lee, John M., Jayakar V. Nayak, Laurie L. Doghramji, Kevin C. Welch, and Alexander G. Chiu. “Assessing the Risk of Irrigation Bottle and Fluid Contamination after Endoscopic Sinus Surgery.” American Journal of Rhinology & Allergy 24, no. 3 (2010): 197–99. https://doi.org/10.2500/ajra.2010.24.3481.

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2008

Leibowitz, Michael S., Jayakar V. Nayak, and Robert L. Ferris. “Head and Neck Cancer Immunotherapy: Clinical Evaluation.” Current Oncology Reports 10, no. 2 (2008): 162–69. https://doi.org/10.1007/s11912-008-0025-8.

Nayak, Jayakar V., Lisa A. Teot, Yatin Vyas, Carl H. Snyderman, Elizabeth H. Toh, and Frederic W.-B. Deleyiannis. “Head and Neck Epithelioid Sarcoma in a Child: Diagnostic Dilemma and Anterolateral Thigh Free Flap Reconstruction.” International Journal of Pediatric Otorhinolaryngology 72, no. 5 (2008): 719–24. https://doi.org/10.1016/j.ijporl.2008.01.032.

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2007

Nayak, Jayakar V., Rohan R. Walvekar, Regiane S. Andrade, Nicole Daamen, Stephen Y. Lai, Athanassios Argiris, Ryan P. Smith, et al. “Deferring Planned Neck Dissection Following Chemoradiation for Stage IV Head and Neck Cancer: The Utility of PET-CT:” The Laryngoscope 117, no. 12 (2007): 2129–34. https://doi.org/10.1097/MLG.0b013e318149e6bc.

Nayak, Jayakar V., Paul A. Gardner, Allan D. Vescan, Ricardo L. Carrau, Amin B. Kassam, and Carl H. Snyderman. “Experience with the Expanded Endonasal Approach for Resection of the Odontoid Process in Rheumatoid Disease.” American Journal of Rhinology 21, no. 5 (2007): 601–6. https://doi.org/10.2500/ajr.2007.21.3089.

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2005

Ferris, Robert L., Barton F. Branstetter, and Jayakar V. Nayak. “Diagnostic Utility of Positron Emission Tomography-Computed Tomography for Predicting Malignancy in Cystic Neck Masses in Adults:” The Laryngoscope 115, no. 11 (2005): 1979–82. https://doi.org/10.1097/01.mlg.0000178328.70288.55.

Zimmer, Lee A., Barton F. Branstetter, Jayakar V. Nayak, and Jonas T. Johnson. “Current Use of 18F-Fluorodeoxyglucose Positron Emission Tomography and Combined Positron Emission Tomography and Computed Tomography in Squamous Cell Carcinoma of the Head and Neck:” The Laryngoscope 115, no. 11 (2005): 2029–34. https://doi.org/10.1097/01.MLG.0000181495.94611.A6.

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2003

Nayak, Jayakar V., J. Thomas Molina, Jonathan C. Smith, Barton F. Branstetter IV, Jennifer L. Hunt, and Carl H. Snyderman. “Myoepithelial Neoplasia of the Submandibular Gland: Case Report and Therapeutic Considerations.” Archives of Otolaryngology–Head & Neck Surgery 129, no. 3 (March 1, 2003): 359. https://doi.org/10.1001/archotol.129.3.359.

Nayak, Jayakar V., James R. Cook, J. Thomas Molina, Matthew P. Branch, Barton F. Branstetter IV, Robert L. Ferris, and Eugene N. Myers. “Primary Lymphoma of the Larynx: New Diagnostic and Therapeutic Approaches.” ORL 65, no. 6 (2003): 321–26. https://doi.org/10.1159/000076049.


Empty Nose Syndrome (ENS) and Upper Airway Physiology

2020

Gill, Amarbir S., Mena Said, Travis T. Tollefson, E. Bradley Strong, Jayakar V. Nayak, and Toby O. Steele. “Patient-Reported Outcome Measures and Provocative Testing in the Workup of Empty Nose Syndrome—Advances in Diagnosis: A Systematic Review.” American Journal of Rhinology & Allergy 34, no. 1 (2020): 134–40. https://doi.org/10.1177/1945892419880642.

Ibrahim, Nour, Matthew A. Tyler, Nicole A. Borchard, Aakanksha Rathor, and Jayakar V. Nayak. “Nasal Vestibular Body Treatment for Recalcitrant Nasal Obstruction.” International Forum of Allergy & Rhinology 10, no. 3 (2020): 388–94. https://doi.org/10.1002/alr.22463.

Malik, Jennifer, Andrew Thamboo, Sachi Dholakia, Nicole A. Borchard, Sam McGhee, Chengyu Li, Kai Zhao, and Jayakar V. Nayak. “The Cotton Test Redistributes Nasal Airflow in Patients with Empty Nose Syndrome.” International Forum of Allergy & Rhinology 10, no. 4 (2020): 539–45. https://doi.org/10.1002/alr.22489.

Thamboo, Andrew, Sachi S. Dholakia, Nicole A. Borchard, Vishal S. Patel, Navarat Tangbumrungtham, Nathalia Velasquez, Zhenxiao Huang, David Zarabanda, Tsuguhisa Nakayama, and Jayakar V. Nayak. “Inferior Meatus Augmentation Procedure (IMAP) to Treat Empty Nose Syndrome: A Pilot Study.” Otolaryngology–Head and Neck Surgery 162, no. 3 (2020): 382–85. https://doi.org/10.1177/0194599819900263.

***

2019

Borchard, Nicole A., Sachi S. Dholakia, Carol H. Yan, David Zarabanda, Andrew Thamboo, and Jayakar V. Nayak. “Use of Intranasal Submucosal Fillers as a Transient Implant to Alter Upper Airway Aerodynamics: Implications for the Assessment of Empty Nose Syndrome.” International Forum of Allergy & Rhinology 9, no. 6 (2019): 681–87. https://doi.org/10.1002/alr.22299.

Manji, Jamil, Vishal S. Patel, Jayakar V. Nayak, and Andrew Thamboo. “Environmental Triggers Associated With Empty Nose Syndrome Symptoms: A Cross-Sectional Study.” Annals of Otology, Rhinology & Laryngology 128, no. 7 (2019): 601–7. https://doi.org/10.1177/0003489419833714.

Talmadge, Jason, Jayakar V. Nayak, William Yao, and Martin J. Citardi. “Management of Postsurgical Empty Nose Syndrome.” Facial Plastic Surgery Clinics of North America 27, no. 4 (2019): 465–75. https://doi.org/10.1016/j.fsc.2019.07.005.

Williams, Ryan, Vishal Patel, Yu-Feng Chen, Navarat Tangbumrungtham, Andrew Thamboo, Sam P. Most, Jayakar V. Nayak, and Stanley Y. C. Liu. “The Upper Airway Nasal Complex: Structural Contribution to Persistent Nasal Obstruction.” Otolaryngology–Head and Neck Surgery 161, no. 1 (2019): 171–77. https://doi.org/10.1177/0194599819838262.

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2018

Manji, Jamil, Jayakar V. Nayak, and Andrew Thamboo. “The Functional and Psychological Burden of Empty Nose Syndrome: Burdens of ENS.” International Forum of Allergy & Rhinology 8, no. 6 (2018): 707–12. https://doi.org/10.1002/alr.22097.

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2017

Thamboo, Andrew, Nathalia Velasquez, Al-Rahim R. Habib, David Zarabanda, Hassan Paknezhad, and Jayakar V. Nayak. “Defining Surgical Criteria for Empty Nose Syndrome: Validation of the Office-Based Cotton Test and Clinical Interpretability of the Validated Empty Nose Syndrome 6-Item Questionnaire: Cotton Test Validation and ENS6Q MCID.” The Laryngoscope 127, no. 8 (2017): 1746–52. https://doi.org/10.1002/lary.26549.

Velasquez, Nathalia, Andrew Thamboo, Al-Rahim R. Habib, Zhenxiao Huang, and Jayakar V. Nayak. “The Empty Nose Syndrome 6-Item Questionnaire (ENS6Q): A Validated 6-Item Questionnaire as a Diagnostic Aid for Empty Nose Syndrome Patients: ENS6Q Diagnostic Aid for ENS.” International Forum of Allergy & Rhinology 7, no. 1 (2017): 64–71. https://doi.org/10.1002/alr.21842.

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2016

Locketz, Garrett D., Neville W. Teo, Evan Walgama, Ian M. Humphreys, and Jayakar V. Nayak. “The Nasal Vestibular Body: Anatomy, Clinical Features, and Treatment Considerations.” European Archives of Oto-Rhino-Laryngology 273, no. 3 (2016): 777–81. https://doi.org/10.1007/s00405-015-3868-2.

Thamboo, Andrew, Nathalia Velasquez, Noel Ayoub, and Jayakar V. Nayak. “Distinguishing Computed Tomography Findings in Patients with Empty Nose Syndrome: Radiologic Findings in ENS.” International Forum of Allergy & Rhinology 6, no. 10 (2016): 1075–82. https://doi.org/10.1002/alr.21774.

***

2015

Velasquez, Nathalia, Zhenxiao Huang, Ian M. Humphreys, and Jayakar V. Nayak. “Inferior Turbinate Reconstruction Using Porcine Small Intestine Submucosal Xenograft Demonstrates Improved Quality of Life Outcomes in Patients with Empty Nose Syndrome: IT Submucosal Restoration Improves QOL in ENS.” International Forum of Allergy & Rhinology 5, no. 11 (2015): 1077–81. https://doi.org/10.1002/alr.21633.


Immunology: Immune Systems and Immunity

2020

Lee, Ivan T., Tsuguhisa Nakayama, Chien-Ting Wu, Yury Goltsev, Sizun Jiang, Phillip A. Gall, Chun-Kang Liao, et al. “Robust ACE2 Protein Expression Localizes to the Motile Cilia of the Respiratory Tract Epithelia and Is Not Increased by ACE Inhibitors or Angiotensin Receptor Blockers.” MedRxiv, May 12, 2020, 2020.05.08.20092866. https://doi.org/10.1101/2020.05.08.20092866.

***

2019

Huang, Zhenxiao, Nathalia Velasquez, Alan Nguyen, Ting Ye, Wei Le, Dawn T. Bravo, Peter H. Hwang, Bing Zhou, and Jayakar V. Nayak. “Topical Corticosteroid Pretreatment Mitigates Cellular Damage After Caustic Injury to the Nasal Upper Airway Epithelium.” American Journal of Rhinology & Allergy 33, no. 3 (2019): 277–85. https://doi.org/10.1177/1945892418823305.

***

2018

Kim, Young Hyo, Tsuguhisa Nakayama, and Jayakar Nayak. “Glycolysis and the Hexosamine Biosynthetic Pathway as Novel Targets for Upper and Lower Airway Inflammation.” Allergy, Asthma & Immunology Research 10, no. 1 (2018): 6. https://doi.org/10.4168/aair.2018.10.1.6.

***

2017

Huang, Zhenxiao, Jayakar V. Nayak, Yan Sun, Qian Huang, and Bing Zhou. “Peripheral Blood T-Helper Cells and Eosinophil Populations in Patients with Atopic and Nonatopic Chronic Rhinosinusitis:” American Journal of Rhinology & Allergy, January 1, 2017. https://doi.org/10.2500/ajra.2017.31.4405.

Böscke, Robert, Eszter K. Vladar, Michael Könnecke, Birgit Hüsing, Robert Linke, Ralph Pries, Norbert Reiling, Jeffrey D. Axelrod, Jayakar V. Nayak, and Barbara Wollenberg. “Wnt Signaling in Chronic Rhinosinusitis with Nasal Polyps.” American Journal of Respiratory Cell and Molecular Biology 56, no. 5 (2017): 575–84. https://doi.org/10.1165/rcmb.2016-0024OC.

Edward, Justin A, Mrinmoy Sanyal, Wei Le, Ethan Soudry, Vijay R Ramakrishnan, Dawn T Bravo, Alan L Nguyen, et al. “Selective Expansion of Human Regulatory T Cells in Nasal Polyps, and Not Adjacent Tissue Microenvironments, in Individual Patients Exposed to Steroids.” Clinical Immunology 179 (2017): 66–76. https://doi.org/10.1016/j.clim.2017.02.002.

Min, Jin-Young, Jayakar V. Nayak, Kathryn E. Hulse, Whitney W. Stevens, Paul A. Raju, Julia H. Huang, Lydia A. Suh, et al. “Evidence for Altered Levels of IgD in the Nasal Airway Mucosa of Patients with Chronic Rhinosinusitis.” Journal of Allergy and Clinical Immunology 140, no. 6 (2017): 1562-1571.e5. https://doi.org/10.1016/j.jaci.2017.05.032.

***

2016

Rashan, Ali R., Eliver Goshn, Asa Peterson, Yang Yang, Meghan Phillips, Bita Sahaf, Leonore Herzenberg, and Jayakar V. Nayak. “Characterization of Immunoglobulin E Plasma Cells That Are Elevated in the Upper Airway Mucosa of Nonatopic Patients with Chronic Rhinosinusitis without Nasal Polyps: IgE Plasmablasts in Nonatopic CRSsNP.” International Forum of Allergy & Rhinology 6, no. 4 (2016): 378–84. https://doi.org/10.1002/alr.21696.

***

2014

Cho, Do-Yeon, Wei Le, Dawn T. Bravo, Peter H. Hwang, Beate Illek, Horst Fischer, and Jayakar V. Nayak. “Air Pollutants Cause Release of Hydrogen Peroxide and Interleukin-8 in a Human Primary Nasal Tissue Culture Model: PM Induced Oxidative Stress in Nasal Tissue.” International Forum of Allergy & Rhinology 4, no. 12 (2014): 966–71. https://doi.org/10.1002/alr.21413.

***

2013

Cho, Do-Yeon, Jayakar V. Nayak, Dawn T. Bravo, Wei Le, Alan Nguyen, Justin A. Edward, Peter H. Hwang, Beate Illek, and Horst Fischer. “Expression of Dual Oxidases and Secreted Cytokines in Chronic Rhinosinusitis: DUOX1/DUOX2 and Secreted Cytokines in CRS.” International Forum of Allergy & Rhinology 3, no. 5 (2013): 376–83. https://doi.org/10.1002/alr.21133.

Edward, Justin A., Mrinmoy Sanyal, Vijay R. Ramakrishnan, Wei Le, Alan L. Nguyen, Todd T. Kingdom, Peter H. Hwang, and Jayakar V. Nayak. “Systemic Prednisone Administration Selectively Alters Granulocyte Subsets in Nasal Polyps from Aspirin-Exacerbated Respiratory Disease and Chronic Rhinosinusitis Patients: Prednisone Alters Granulocytes in Nasal Polyps.” International Forum of Allergy & Rhinology 3, no. 11 (2013): 866–76. https://doi.org/10.1002/alr.21221.

***

2010

Figures, Mindy R., Jayakar V. Nayak, Carl Gable, and Alexander G. Chiu. “Sinonasal Seromucinous Hamartomas: Clinical Features and Diagnostic Dilemma.” Otolaryngology–Head and Neck Surgery 143, no. 1 (2010): 165–66. https://doi.org/10.1016/j.otohns.2009.11.014.

***

2009

Cohen, Michael, Jennifer Kofonow, Jayakar V. Nayak, James N. Palmer, Alexander G. Chiu, Jeff G. Leid, and Noam A. Cohen. “Biofilms in Chronic Rhinosinusitis: A Review.” American Journal of Rhinology & Allergy 23, no. 3 (2009): 255–60. https://doi.org/10.2500/ajra.2009.23.3319.

***

2006

López-Albaitero, Andrés, Jayakar V. Nayak, Takeshi Ogino, Avinash Machandia, William Gooding, Albert B. DeLeo, Soldano Ferrone, and Robert L. Ferris. “Role of Antigen-Processing Machinery in the In Vitro Resistance of Squamous Cell Carcinoma of the Head and Neck Cells to Recognition by CTL.” The Journal of Immunology 176, no. 6 (March 15, 2006): 3402–9. https://doi.org/10.4049/jimmunol.176.6.3402.

Nayak, Jayakar V., David A. Hokey, Adriana Larregina, Yukai He, Russell D. Salter, Simon C. Watkins, and Louis D. Falo. “Phagocytosis Induces Lysosome Remodeling and Regulated Presentation of Particulate Antigens by Activated Dendritic Cells.” The Journal of Immunology 177, no. 12 (December 15, 2006): 8493–8503. https://doi.org/10.4049/jimmunol.177.12.8493.

***

2005

Yu, Paul B., William Parker, Jayakar V. Nayak, and Jeffrey L. Platt. “Sensitization with Xenogeneic Tissues Alters the Heavy Chain Repertoire of Human Anti-Gal??1???3Gal Antibodies:” Transplantation 80, no. 1 (2005): 102–9. https://doi.org/10.1097/01.TP.0000162976.07023.6D.

***

2003

Dileo, John, Rajkumar Banerjee, Mark Whitmore, Jayakar V Nayak, Louis D Falo, and Leaf Huang. “Lipid–Protamine–DNA-Mediated Antigen Delivery to Antigen-Presenting Cells Results in Enhanced Anti-Tumor Immune Responses.” Molecular Therapy 7, no. 5 (2003): 640–48. https://doi.org/10.1016/S1525-0016(03)00064-9.


Stem Cell / Regenerative Medicine for Upper Airway Diseases

2020

Vaidyanathan, Sriram, Ameen A. Salahudeen, Zachary M. Sellers, Dawn T. Bravo, Shannon S. Choi, Arpit Batish, Wei Le, et al. “High-Efficiency, Selection-Free Gene Repair in Airway Stem Cells from Cystic Fibrosis Patients Rescues CFTR Function in Differentiated Epithelia.” Cell Stem Cell 26, no. 2 (2020): 161-171.e4. https://doi.org/10.1016/j.stem.2019.11.002.

***

2014

Cho, Kyu-Sup, Hee-Young Park, Hwan-Jung Roh, Dawn T. Bravo, Peter H. Hwang, and Jayakar V. Nayak. “Human Ethmoid Sinus Mucosa: A Promising Novel Tissue Source of Mesenchymal Progenitor Cells.” Stem Cell Research & Therapy 5, no. 1 (January 24, 2014): 15. https://doi.org/10.1186/scrt404.

***

2013

Bravo, Dawn T., Ethan Soudry, Justin A. Edward, Wei Le, Alan L. Nguyen, Peter H. Hwang, Mrinmoy Sanyal, and Jayakar V. Nayak. “Characterization of Human Upper Airway Epithelial Progenitors.” International Forum of Allergy & Rhinology 3, no. 10 (October 2013): 841–47. https://doi.org/10.1002/alr.21205.