PhySH "Physician Scientist Hour"
INDE 217 : Physician Scientist Hour (PhySH)
Mondays at 12:15pm - 1:15pm (VIRTUAL for Autumn 2021)
PhySH is virtual (via Zoom) for Autumn 2021. We hope to return to an IN-PERSON format for the rest of the 2021-2022 academic year.
Please register for PhySH - INDE 217
(You are not required to register to attend.)
You might also be interested in the TRAM lecture series, which hosts speakers who are recognized leaders in translational research and applied medicine. Please see the Translational Research and Applied Medicine website for more information.
Autumn 2021 PhySH Schedule
We will provide updates as information becomes available.
September 20, 2021
Managing up, down and across: How to have productive, stress-free relationships at work (RCR)
Dr. Boothroyd’s research interests have spanned from viruses such as bacteriophage T7 and Foot and Mouth Disease Virus through to protozoan parasites such as Trypanosoma brucei, the cause of African sleeping sickness, and Toxoplasma gondii, a serious pathogen in newborns and individuals who are immunocompromised. Currently, his lab is focused on the interaction between the animal host and Toxoplasma. Together with their collaborators, the lab asks: (1) how does Toxoplasma invade and co-opt almost any cell type from almost any animal; (2) once in, how does it persist in its hosts for their entire lifetime; and 3) how do the polymorphic “effectors” that Toxoplasma injects into a host cell produce different disease outcomes.
Allison Rustagi (UCSF)
October 4, 2021
Parenting as a physician-scientist: Research, personal stories, and opportunities for change
Dr. Rustagi obtained a bachelor’s in Human Biology from Stanford University, an M.D. from UCSF and a Ph.D. in Epidemiology from the University of Washington, in which she found cervical cancer screening reduces mortality among women even up to age 79. During her post-doctoral Fellowship in Global Health at the University of Washington, she conducted a cluster randomized trial of quality improvement interventions in sub-Saharan Africa, which increased uptake of interventions that reduce mother-to-child HIV transmission. Her current research focuses on implementation of lung cancer screening in the VA; she also has an interest in gender discrimination in medicine.
October 11, 2021
Understanding and modeling aging
Dr. Brunet’s lab is interested in the molecular mechanisms of aging and longevity, with a particular emphasis on the nervous system. Her lab is interested in identifying pathways involved in delaying aging in response to external stimuli such as availability of nutrients and mates. She also seeks to understand the mechanisms that influence the rejuvenation of old stem cells. Finally, her lab has pioneered the naturally short-lived African killifish as a new model to explore the regulation of aging and age-related diseases.
October 18, 2021
From parasites to plankton: The opportunities and challenges of switching fields
Dr. Yeh’s research focuses on the apicoplast, a prokaryotically-derived plastid organelle unique to Plasmodium (and other pathogenic Apicomplexa parasites) and a key anti-malarial drug target. Her laboratory's goal is to elucidate apicoplast biology, function, and role in pathogenesis with the ultimate goal of realizing the potential of the apicoplast as a therapeutic target.
October 25, 2021
Dr. Abu-Remaileh’s lab is interested in identifying novel pathways that enable cellular and organismal adaptation to metabolic stress and changes in environmental conditions. It also study how these pathways go awry in human diseases such as cancer, neurodegeneration and metabolic syndrome, in order to engineer new therapeutic modalities. By examining 1) how the lysosome communicates with other cellular compartments to fulfill the metabolic demands of the cell under various metabolic states, 2) and how its dysfunction leads to rare and common human diseases, his lab hopes to engineer novel therapies to modulate the pathways that govern human disease..
November 1, 2021
High-throughput genomics in cancer immunotherapy
Dr. Satpathy’s lab works at the interface of immunology, cancer biology, and genomics to study cellular and molecular mechanisms of the immune response to cancer. In particular, it is leveraging high-throughput genomic technologies to understand the dynamics of the tumor-specific T cell response to cancer antigens and immunotherapies (checkpoint blockade, CAR-T cells, and others). The lab is also interested in understanding the impact of immuno-editing on the heterogeneity and clonal evolution of cancer.
November 8, 2021
Dr. Idoyaga’s lab is focused on the function and biology of dendritic cells, which are specialized antigen-presenting cells that initiate and modulate our body’s immune responses. Considering their importance in orchestrating the quality and quantity of immune responses, dendritic cells are an indisputable target for vaccines and therapies.
MSTP Town Hall
November 15, 2021