Mormino Lab Publications

Early Tau accumulation is detected within the medial temporal lobe using Tau PET imaging. 

Featured Publication

Post-translational modifications linked to preclinical Alzheimer's disease-related pathological and cognitive changes.

Abiose O, Rutledge J, Moran-Losada P, Belloy ME, Wilson EN, He Z, Trelle AN, Channappa D, Romero A, Park J, Yutsis MV, Sha SJ, Andreasson KI, Poston KL, Henderson VW, Wagner AD, Wyss-Coray T, Mormino EC.Alzheimers Dement. 2024 Mar;20(3):1851-1867. doi: 10.1002/alz.13576. Epub 2023 Dec 25.PMID: 38146099

Senior Author Papers

Younes K, Smith V, Johns E, Carlson ML, Winer J, He Z, Henderson VW, Greicius MD, Young CB, Mormino ECTemporal tau asymmetry spectrum influences divergent behavior and language patterns in Alzheimer's disease. Alzheimer's Disease Neuroimaging Initiative Researchers.Brain Behav Immun. 2024 Jul;119:807-817. doi: 10.1016/j.bbi.2024.05.002. Epub 2024 May 6.PMID: 38710339

Young CB, Smith V, Karjadi C, Grogan SM, Ang TFA, Insel PS, Henderson VW, Sumner M, Poston KL, Au R, Mormino EC. Speech patterns during memory recall relates to early tau burden across adulthood. Alzheimers Dement. 2024 Apr;20(4):2552-2563. doi: 10.1002/alz.13731. Epub 2024 Feb 13.PMID: 38348772 

Abiose O, Rutledge J, Moran-Losada P, Belloy ME, Wilson EN, He Z, Trelle AN, Channappa D, Romero A, Park J, Yutsis MV, Sha SJ, Andreasson KI, Poston KL, Henderson VW, Wagner AD, Wyss-Coray T, Mormino EC. Post-translational modifications linked to preclinical Alzheimer's disease-related pathological and cognitive changes. Alzheimers Dement. 2024 Mar;20(3):1851-1867. doi: 10.1002/alz.13576. Epub 2023 Dec 25.PMID: 38146099 

Close Local Collaborators

Rutledge J, Lehallier B, Zarifkar P, Losada PM, Shahid-Besanti M, Western D, Gorijala P, Ryman S, Yutsis M, Deutsch GK, Mormino E, Trelle A, Wagner AD, Kerchner GA, Tian L, Cruchaga C, Henderson VW, Montine TJ, Borghammer P, Wyss-Coray T, Poston KL. Comprehensive proteomics of CSF, plasma, and urine identify DDC and other biomarkers of early Parkinson's disease. Acta Neuropathol. 2024 Mar 11;147(1):52. doi: 10.1007/s00401-024-02706-0.PMID: 38467937 

Winer JR, Lok R, Weed L, He Z, Poston KL, Mormino EC, Zeitzer JM. Impaired 24-h activity patterns are associated with an increased risk of Alzheimer's disease, Parkinson's disease, and cognitive decline. Alzheimers Res Ther. 2024 Feb 14;16(1):35. doi: 10.1186/s13195-024-01411-0.PMID: 38355598

Fettahoglu A, Zhao M, Khalighi M, Vossler H, Jovin M, Davidzon G, Zeineh M, Boada F, Mormino E, Henderson VW, Moseley M, Chen KT, Zaharchuk G. Early-Frame [18F]Florbetaben PET/MRI for Cerebral Blood Flow Quantification in Patients with Cognitive Impairment: Comparison to an [15O]Water Gold Standard. J Nucl Med. 2024 Feb 1;65(2):306-312. doi: 10.2967/jnumed.123.266273.PMID: 38071587

Oh HS, Rutledge J, Nachun D, Pálovics R, Abiose O, Moran-Losada P, Channappa D, Urey DY, Kim K, Sung YJ, Wang L, Timsina J, Western D, Liu M, Kohlfeld P, Budde J, Wilson EN, Guen Y, Maurer TM, Haney M, Yang AC, He Z, Greicius MD, Andreasson KI, Sathyan S, Weiss EF, Milman S, Barzilai N, Cruchaga C, Wagner AD, Mormino E, Lehallier B, Henderson VW, Longo FM, Montgomery SB, Wyss-Coray T. Organ aging signatures in the plasma proteome track health and disease. Nature. 2023 Dec;624(7990):164-172. doi: 10.1038/s41586-023-06802-1. Epub 2023 Dec 6.PMID: 38057571 

Smith V, Younes K, Poston KL, Mormino EC, Young CB. Reliability of remote National Alzheimer's Coordinating Center Uniform Data Set data. Alzheimers Dement (Amst). 2023 Nov 29;15(4):e12498. doi: 10.1002/dad2.12498. eCollection 2023 Oct-Dec.PMID: 38034852 

Phongpreecha T, Godrich D, Berson E, Espinosa C, Kim Y, Cholerton B, Chang AL, Mataraso S, Bukhari SA, Perna A, Yakabi K, Montine KS, Poston KL, Mormino E, White L, Beecham G, Aghaeepour N, Montine TJ. Quantitative estimate of cognitive resilience and its medical and genetic associations. Alzheimers Res Ther. 2023 Nov 6;15(1):192. doi: 10.1186/s13195-023-01329-z.PMID: 37926851