Publications

2019

Zinc-Chelating Small Molecules Preferentially Accumulate and Function within Pancreatic β Cells.
Horton TM, Allegretti PA, Lee S, Moeller HP, Smith M, Annes JP.  Cell Chem Biol. 2019 Feb 21;26(2):213-222.e6. doi: 10.1016/j.chembiol.2018.10.019. Epub 2018 Dec 6.

Fluorescent Triazole Urea Activity‐Based Probes for the Single‐Cell Phenotypic Characterization of Staphylococcus aureus.
Linhai Chen  Laura J. Keller  Edward Cordasco, Matthew Bogyo, Christian S. Lentz. Angew Chem Int Ed. 2019, 58, 5643-5647. 

2018

CC-401 Promotes β-Cell Replication via Pleiotropic Consequences of DYRK1A/B Inhibition.
Abdolazimi Y, Lee S, Xu H, Allegretti P, Horton TM, Yeh B, Moeller HP, Nichols RJ, McCutcheon D, Shalizi A, Smith M, Armstrong NA, Annes JP. (2018) Endocrinology. 2018 Sep 1;159(9):3143-3157. doi: 10.1210/en.2018-00083. PubMed PMID: 29514186.

Protein-Based Inheritance: Epigenetics beyond the Chromosome
Zachary H Harvey, Yiwen Chen, Daniel F Jarosz.  Molecular Cell.  2018 Jan 18;69(2): 195-202.  PMID: 29153393. PMCID: PMC5775936.

Interaction of mitochondrial fission factor with dynamin related protein 1 governs physiological mitochondrial function in vivo. 
Kornfeld OS, Qvit N, Haileselassie B, Shamloo M, Bernardi P, and Mochly-Rosen D.  Sci Rep. 2018 Sept 19;8(1):14034.  PMID: 30232469.  PMCID: PMC6145916.

2017

Protein-Based Inheritance: Epigenetics Beyond The Chromosome.
Harvey ZH, Chen Y, Jarosz DF. (2017) Mol Cell. 2017 Nov 15. pii: S1097-2765(17)30807-9. doi: 10.1016/j.molcel.2017.10.030. Review.

2016

Engineered substrate-specific delta PKC antagonists to enhance cardiac therapeutics.
Qvit N, Kornfeld OS, Mochly-Rosen D. (2016) Angew Chem Int Ed Engl. 2016 Dec 12. doi: 10.1002/anie.201605429.

Correcting mitochondrial fusion by manipulating mitofusin conformations.
Franco A, Kitsis RN, Fleischer JA, Gavathiotis E, Kornfeld OS, Gong G, Biris N, Benz A, Qvit N, Donnelly SK, Chen Y, Mennerick S, Hodgson L, Mochly-Rosen D, Dorn GW II. (2016) Nature. 2016 Dec 1. doi: 10.1038/nature20156.

The entangled ER-mitochondrial axis as a potential therapeutic strategy in neurodegeneration: A tangled duo unchained.
Joshi AU, Kornfeld OS, Mochly-Rosen D. (2016) Cell Calcium. 2016 Sep. doi: 10.1016/j.ceca.2016.04.010.

Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation.
Qvit N, Kornfeld OS. (2016) J Vis Exp. 2016 Jan 26. doi: 10.3791/53589.

2015

Mitochondrial reactive oxygen species at the heart of the matter: new therapeutic approaches for cardiovascular diseases.
Kornfeld OS, Hwang S, Disatnik MH, Chen CH, Qvit N, Mochly-Rosen D. (2015) Circ Res. 2015 May 22. doi: 10.1161/CIRCRESAHA.116.305432.