MIPS member publications

This service is a new work in progress with the aim to communicate MIPS research developments and foster collaborations amongst members as well as the broader molecular imaging and theragnostics communities.

MIPS members: contact Jason Thanh Lee to list your publications or offer suggestions on how best to structure this page to be most effective.

Ha B, Liang K, Liu C, Melemenidis S, Manjappa R, Viswanathan V, Das N, Ashraf R, Lau B, Soto L, Graves EE, Rao J, Loo BW Jr, Pratx G. Real-time optical oximetry during FLASH radiotherapy using a phosphorescent nanoprobe. Radiother Oncol. 2022 Aug 11:S0167-8140(22)04232-3. doi: 10.1016/j.radonc.2022.08.011. Epub ahead of print. PMID: 35964762.

Seo JW, Ajenjo J, Wu B, Robinson E, Raie MN, Wang J, Tumbale SK, Buccino P, Anders DA, Shen B, Habte FG, Beinat C, James ML, Reyes ST, Ravindra Kumar S, Miles TF, Lee JT, Gradinaru V, Ferrara KW. Multimodal imaging of capsid and cargo reveals differential brain targeting and liver detargeting of systemically-administered AAVs. Biomaterials. 2022 Aug 6:121701. doi: 10.1016/j.biomaterials.2022.121701. Epub ahead of print. PMID: 35985893.

Lee YJ, van den Berg NS, Duan H, Azevedo EC, Ferri V, Hom M, Raymundo RC, Valencia A, Castillo J, Shen B, Zhou Q, Freeman L, Koran ME, Kaplan MJ, Colevas AD, Baik FM, Chin FT, Martin BA, Iagaru A, Rosenthal EL. 89Zr-panitumumab combined with 18F-FDG-PET improves detection and staging of head and neck squamous cell carcinoma. Clin Cancer Res. 2022 Aug 5:CCR-22-0094. doi: 10.1158/1078-0432.CCR-22-0094. Epub ahead of print. PMID: 35929985.

Foiret J, Cai X, Bendjador H, Park EY, Kamaya A, Ferrara KW. Improving plane wave ultrasound imaging through real-time beamformation across multiple arrays. Sci Rep. 2022 Aug 4;12(1):13386. doi: 10.1038/s41598-022-16961-2. PMID: 35927389; PMCID: PMC9352764.

Lautman Z, Winetraub Y, Blacher E, Yu C, Terem I, Chibukhchyan A, Marshel JH, de la Zerda A. Intravital 3D visualization and segmentation of murine neural networks at micron resolution. Sci Rep. 2022 Jul 30;12(1):13130. doi: 10.1038/s41598-022-14450-0. PMID: 35907928; PMCID: PMC9338956.

Xiao Z, Alam IS, Simonetta F, Chen W, Scheller L, Murty S, Lohmeyer JK, Lopes Ramos TL, James ML, Negrin RS, Gambhir SS. ICOS ImmunoPET Enables Visualization of Activated T Cells and Early Diagnosis of Murine Acute Gastrointestinal GvHD. Blood Adv. 2022 Jul 5:bloodadvances.2022007403. doi: 10.1182/bloodadvances.2022007403. Epub ahead of print. PMID: 35790103.

Rashidi A, Theruvath AJ, Huang CH, Wu W, Mahmoud EE, Jesu Raj JG, Marycz K, Daldrup-Link HE. Vascular injury of immature epiphyses impair stem cell engraftment in cartilage defects. Sci Rep. 2022 Jul 9;12(1):11696. doi: 10.1038/s41598-022-15721-6. PMID: 35810189; PMCID: PMC9271080.

Padwal J, Baratto L, Chakraborty A, Hawk K, Spunt S, Avedian R, Daldrup-Link HE. PET/MR of pediatric bone tumors: what the radiologist needs to know. Skeletal Radiol. 2022 Jul 9. doi: 10.1007/s00256-022-04113-6. Epub ahead of print. PMID: 35804163.

Rashidi A, Baratto L, Theruvath AJ, Greene EB, Hawk KE, Lu R, Link MP, Spunt SL, Daldrup-Link HE. Diagnostic Accuracy of 2-[18F]FDG-PET and whole-body DW-MRI for the detection of bone marrow metastases in children and young adults. Eur Radiol. 2022 Jul;32(7):4967-4979. doi: 10.1007/s00330-021-08529-x. Epub 2022 Jan 31. PMID: 35099603; PMCID: PMC9232918.

Bendjador H, Foiret J, Wodnicki R, Stephens DN, Krut Z, Park EY, Gazit Z, Gazit D, Pelled G, Ferrara KW. A theranostic 3D ultrasound imaging system for high resolution image-guided therapy. Theranostics. 2022 Jun 27;12(11):4949-4964. doi: 10.7150/thno.71221. PMID: 35836805; PMCID: PMC9274734.

Jackson IM, Webb EW, Scott PJH, James ML. In Silico Approaches for Addressing Challenges in CNS Radiopharmaceutical Design. ACS Chem Neurosci. 2022 Jun 15;13(12):1675-1683. doi: 10.1021/acschemneuro.2c00269. Epub 2022 May 23. PMID: 35606334.

Duan H, Ferri V, Fisher GA, Shaheen S, Davidzon GA, Iagaru A, Mari Aparici C. Evaluation of Liver and Renal Toxicity in Peptide Receptor Radionuclide Therapy for Somatostatin Receptor Expressing Tumors: A 2-Year Follow-Up. Oncologist. 2022 Jun 8;27(6):447-452. doi: 10.1093/oncolo/oyab072. PMID: 35641196; PMCID: PMC9177120.

Pal R, Hom ME, van den Berg NS, Lwin TM, Lee YJ, Prilutskiy A, Faquin W, Yang E, Saladi SV, Varvares MA, Rosenthal EL, Kumar ATN. First Clinical Results of Fluorescence Lifetime-enhanced Tumor Imaging Using Receptor-targeted Fluorescent Probes. Clin Cancer Res. 2022 Jun 1;28(11):2373-2384. doi: 10.1158/1078-0432.CCR-21-3429. PMID: 35302604; PMCID: PMC9167767.

Pemmaraju R, Minahan R, Wang E, Schadl K, Daldrup-Link H, Habte F. Web-Based Application for Biomedical Image Registry, Analysis, and Translation (BiRAT). Tomography. 2022 May 30;8(3):1453-1462. doi: 10.3390/tomography8030117. PMID: 35736865; PMCID: PMC9228304.

Jackson IM, Buccino PJ, Azevedo EC, Carlson ML, Luo ASZ, Deal EM, Kalita M, Reyes ST, Shao X, Beinat C, Nagy SC, Chaney AM, Anders DA, Scott PJH, Smith M, Shen B, James ML. Radiosynthesis and initial preclinical evaluation of [11C]AZD1283 as a potential P2Y12R PET radiotracer. Nucl Med Biol. 2022 May 20:S0969-8051(22)00049-X. doi: 10.1016/j.nucmedbio.2022.05.001. Epub ahead of print. PMID: 35680502.

Xie J, El Rami F, Zhou K, Simonetta F, Chen Z, Zheng X, Chen M, Balakrishnan PB, Dai SY, Murty S, Alam IS, Baker J, Negrin RS, Gambhir SS, Rao J. Multiparameter Longitudinal Imaging of Immune Cell Activity in Chimeric Antigen Receptor T Cell and Checkpoint Blockade Therapies. ACS Cent Sci [Internet]. American Chemical Society; 2022 May 12

Duan H, Baratto L, Fan RE, Soerensen SJC, Liang T, Chung BI, Thong AEC, Gill H, Kunder C, Stoyanova T, Rusu M, Loening AM, Ghanouni P, Davidzon GA, Moradi F, Sonn GA, Iagaru A. Correlation of 68Ga-RM2 PET with Post-Surgery Histopathology Findings in Patients with Newly Diagnosed Intermediate- or High-Risk Prostate Cancer. J Nucl Med. 2022 May 1;jnumed.122.263971.

Farshad Moradi, Heying Duan, Hong Song, Guido A Davidzon, Benjamin I Chung, Alan E C Thong, Andreas M Loening, Pejman Ghanouni, Geoffrey Sonn and Andrei Iagaru. 68Ga-PSMA-11 PET/MRI in patients with newly diagnosed intermediate or high-risk prostate adenocarcinoma: PET findings correlate with outcomes after definitive treatment. Journal of Nuclear Medicine. May 2022, jnumed.122.263897; DOI: https://doi.org/10.2967/jnumed.122.263897

Jiang Y, Zhang Z, Yuan Q, Wang W, Wang H, Li T, Huang W, Xie J, Chen C, Sun Z, Yu J, Xu Y, Poultsides GA, Xing L, Zhou Z, Li G, Li R. Predicting peritoneal recurrence and disease-free survival from CT images in gastric cancer with multitask deep learning: a retrospective study. Lancet Digit Health. 2022 May;4(5):e340-e350. doi: 10.1016/S2589-7500(22)00040-1. PMID: 35461691.

Zhang M, Zhou Q, Huang C, Chan CT, Wu W, Li G, Lim M, Gambhir SS, Daldrup-Link HE. In Vivo Evaluation of Near-Infrared Fluorescent Probe for TIM3 Targeting in Mouse Glioma. Mol Imaging Biol. 2022 Apr;24(2):280-287. doi: 10.1007/s11307-021-01667-0. Epub 2021 Nov 30. PMID: 34846678; PMCID: PMC9254586.

Bose et al. Engineered Cell-Derived Vesicles Displaying Targeting Peptide and Functionalized with Nanocarriers for Therapeutic microRNA Delivery to Triple-Negative Breast Cancer in Mice. Adv Healthc Mater. 2022.

Chen et al. Alternative medicine: therapeutic effects on gastric original signet ring carcinoma via ascorbate and combination with sodium alpha lipoate. BMC Complement Med Ther. 2022.

Cui et al. 3D computational model of oxygen depletion kinetics in brain vasculature during FLASH RT and its implications for in vivo oximetry experiments. Med Phys. 2022.

Duan et al. Reduced Acquisition Time per Bed Position for PET/MRI Using 68Ga-RM2 or 68Ga-PSMA-11 in Patients With Prostate Cancer: A Retrospective Analysis. AJR Am J Roentgenol. 2022.

Eke et al. Long-term expression changes of immune-related genes in prostate cancer after radiotherapy. Cancer Immunol Immunother. 2022.

Hu et al. Detection and Characterization of Sentinel Lymph Node by Ultrasound Molecular Imaging with B7-H3-Targeted Microbubbles in Orthotopic Breast Cancer Model in Mice. Mol Imaging Biol. 2022.

Kim et al. A red fluorescent protein with improved monomericity enables ratiometric voltage imaging with ASAP3. Sci Rep. 2022.

Lecler et al. Comparison between 7 Tesla and 3 Tesla MRI for characterizing orbital lesions. Diagn Interv Imaging. 2022.

Liu et al. Reversibly Photoswitching Upconversion Nanoparticles for Super-Sensitive Photoacoustic Molecular Imaging. Angew Chem Int Ed Engl. 2022.

Shen et al. Novel-view X-ray projection synthesis through geometry-integrated deep learning. Med Image Anal. 2022.

Zhao et al. Using arterial spin labeling to measure cerebrovascular reactivity in Moyamoya disease: Insights from simultaneous PET/MRI. J Cereb Blood Flow Metab. 2022.

Kim Y, Jung HJ, Lee Y, Koo S, Thangam R, Jang WY, Kim SY, Park S, Lee S, Bae G, Patel KD, Wei Q, Lee KB, Paulmurugan R, Jeong WK, Hyeon T, Kim D, Kang H. Manipulating Nanoparticle Aggregates Regulates Receptor-Ligand Binding in Macrophages. J Am Chem Soc. 2022 Apr 6;144(13):5769-5783. doi: 10.1021/jacs.1c08861. Epub 2022 Mar 11. PMID: 35275625.

Gao H, Liu J, Lin Y, Gan GN, Pratx G, Wang F, Langen K, Bradley JD, Rotondo RL, Li HH, Chen RC. Simultaneous dose and dose rate optimization (SDDRO) of the FLASH effect for pencil-beam-scanning proton therapy. Med Phys. 2022 Mar;49(3):2014-2025. doi: 10.1002/mp.15356. Epub 2021 Dec 7. PMID: 34800301; PMCID: PMC8917068.

Alongi P, Laudicella R, Lanzafame H, Farolfi A, Mapelli P, Picchio M, Burger IA, Iagaru A, Minutoli F, Evangelista L. PSMA and Choline PET for the Assessment of Response to Therapy and Survival Outcomes in Prostate Cancer Patients: A Systematic Review from the Literature. Cancers (Basel). 2022 Mar 31;14(7):1770. doi: 10.3390/cancers14071770. PMID: 35406542; PMCID: PMC8997431.

Quan Zhou, Nynke S. van den Berg, Wenying Kang, Jacqueline Pei, Naoki Nishio, Stan van Keulen, Myrthe A. Engelen, Yu-Jin Lee, Marisa Hom, Johana C. M. Vega Leonel, Zachary Hart, Hannes Vogel, Romain Cayrol, Brock A. Martin, Mark Roesner, Glenn Shields, Natalie Lui, Melanie Hayden Gephart, Roan C. Raymundo, Grace Yi, Monica Granucci, Gerald A. Grant, Gordon Li and Eben L. Rosenthal. Factors for differential outcome across cancers in clinical molecular-targeted fluorescence imaging. J Nucl Med 2022 Published March 24, 2022 as doi:10.2967/jnumed.121.263674

Turco S, Tiyarattanachai T, Ebrahimkheil K, Eisenbrey J, Kamaya A, Mischi M, Lyshchik A, El Kaffas A. Interpretable machine learning for characterization of focal liver lesions by contrast-enhanced ultrasound. IEEE Trans Ultrason Ferroelectr Freq Control. 2022 Mar 23;PP. doi: 10.1109/TUFFC.2022.3161719. Epub ahead of print. PMID: 35320099.

Zhao MY, Fan AP, Chen DY, Ishii Y, Khalighi MM, Moseley M, Steinberg GK, Zaharchuk G. Using arterial spin labeling to measure cerebrovascular reactivity in Moyamoya disease: Insights from simultaneous PET/MRI. J Cereb Blood Flow Metab. 2022 Mar 2:271678X221083471. doi: 10.1177/0271678X221083471. Epub ahead of print. PMID: 35236136.

Minamimoto R, Baratto L, Iagaru A. Association Between Time Since Administration of Pegylated G-CSF (Pegfilgrastim) and Bone Marrow Uptake on FDG PET/CT: Determination of a Minimum Interval. AJR Am J Roentgenol. 2022 Feb;218(2):351-358. doi: 10.2214/AJR.21.26480. Epub 2021 Sep 1. PMID: 34467784.

Filipiak P, Shepherd T, Lin YC, Placantonakis DG, Boada FE, Baete SH. Performance of orientation distribution function-fingerprinting with a biophysical multicompartment diffusion model. Magn Reson Med. 2022 Feb 28. doi: 10.1002/mrm.29208. Epub ahead of print. PMID: 35225365.

Wardak M, Sonni I, Fan AP, Minamimoto R, Jamali M, Hatami N, Zaharchuk G, Fischbein N, Nagpal S, Li G, Koglin N, Berndt M, Bullich S, Stephens AW, Dinkelborg LM, Abel T, Manning HC, Rosenberg J, Chin FT, Sam Gambhir S, Mittra ES. 18F-FSPG PET/CT Imaging of System xC- Transporter Activity in Patients with Primary and Metastatic Brain Tumors. Radiology. 2022 Feb 22:203296. doi: 10.1148/radiol.203296. Epub ahead of print. PMID: 35191738.

McLellan CA, Siefe C, Casar JR, Peng CS, Fischer S, Lay A, Parakh A, Ke F, Gu XW, Mao W, Chu S, Goodman MB, Dionne JA. Engineering Bright and Mechanosensitive Alkaline-Earth Rare-Earth Upconverting Nanoparticles. J Phys Chem Lett. 2022 Feb 17;13(6):1547-1553. doi: 10.1021/acs.jpclett.1c03841. Epub 2022 Feb 8. PMID: 35133831.

Ravi N, Chang SE, Franco LM, Nagamani SCS, Khatri P, Utz PJ, Wang SX. A GMR-based assay for quantification of the human response to influenza. Biosens Bioelectron. 2022 Feb 17;205:114086. doi: 10.1016/j.bios.2022.114086. Epub ahead of print. PMID: 35192997.

Lucot KL, Stevens MY, Bonham TA, Azevedo EC, Chaney AM, Webber ED, Jain P, Klockow JL, Jackson IM, Carlson ML, Graves EE, Montine TJ, James ML. Tracking innate immune activation in a mouse model of Parkinson's disease using TREM1 and TSPO PET tracers. J Nucl Med. 2022 Feb 17:jnumed.121.263039. doi: 10.2967/jnumed.121.263039. Epub ahead of print. PMID: 35177426.

Cover Article
Goreke U, Bode A, Yaman S, Gurkan UA, Durmus NG. Size and density measurements of single sickle red blood cells using microfluidic magnetic levitation. Lab Chip. 2022 Feb 15;22(4):683-696. doi: 10.1039/d1lc00686j. PMID: 35094036.

Liu C, Zheng X, Dai T, Wang H, Chen X, Chen B, Sun T, Wang F, Chu S, Rao J. Reversibly Photoswitching Upconversion Nanoparticles for Super-Sensitive Photoacoustic Molecular Imaging. Angew Chem Int Ed Engl. 2022 Feb 9:e202116802. doi: 10.1002/anie.202116802. Epub ahead of print. PMID: 35139242.

Sodji QH, Harris JP, Quon A, Modlin LA, Lau B, Jiang A, Trakul N, Maxim PG, Diehn M, Loo BW Jr, Hiniker SM. Detection of Recurrence After Thoracic Stereotactic Ablative Radiotherapy Using FDG-PET-CT. Clin Lung Cancer. 2022 Feb 4:S1525-7304(22)00010-9. doi: 10.1016/j.cllc.2022.01.006. Epub ahead of print. PMID: 35246393.

Di Ianni T, Airan RD. Deep-fUS: A deep learning platform for functional ultrasound imaging of the brain using sparse data. IEEE Trans Med Imaging. 2022 Feb 2;PP. doi: 10.1109/TMI.2022.3148728. Epub ahead of print. PMID: 35108201.

Louise Kiru, Aimen Zlitni, Aidan Michael Tousley, Guillermo Nicolás Dalton, Wei Wu, Famyrah Lafortune, Anna Liu, Kristen May Cunanan, Hossein Nejadnik, Todd Sulchek, Michael Eugene Moseley, Robbie G. Majzner, Heike Elisabeth Daldrup-Link. In vivo imaging of nanoparticle-labeled CAR T cells. PNAS. Feb 2022, 119 (6) e2102363119; DOI: 10.1073/pnas.2102363119
Paper discussed in "Diving into Imaging Science" ESMI podcast

Jung KO, Theruvath AJ, Nejadnik H, Liu A, Xing L, Sulchek T, Daldrup-Link HE, Pratx G. Mechanoporation enables rapid and efficient radiolabeling of stem cells for PET imaging. Sci Rep. 2022 Feb 22;12(1):2955. doi: 10.1038/s41598-022-06938-6. PMID: 35194089; PMCID: PMC8863797.

Yoon D, Xu Y, Cipriano PW, Alam IS, Mari Aparici C, Tawfik VL, Curtin CM, Carroll IR, Biswal S. Neurovascular, Muscle, and Skin Changes on [18F]FDG PET/MRI in Complex Regional Pain Syndrome of the Foot: A Prospective Clinical Study. Pain Med. 2022 Feb 1;23(2):339-346. doi: 10.1093/pm/pnab315. PMID: 34718774; PMCID: PMC8807071.

Rashidi A, Baratto L, Theruvath AJ, Greene EB, Hawk KE, Lu R, Link MP, Spunt SL, Daldrup-Link HE. Diagnostic Accuracy of 2-[18F]FDG-PET and whole-body DW-MRI for the detection of bone marrow metastases in children and young adults. Eur Radiol. 2022 Jan 31. doi: 10.1007/s00330-021-08529-x. Epub ahead of print. PMID: 35099603.

Wang H, Vilches-Moure JG, Bettinger T, Cherkaoui S, Lutz A, Paulmurugan R. Contrast Enhanced Ultrasound Molecular Imaging of Spontaneous Chronic Inflammatory Bowel Disease in an Interleukin-2 Receptor α-/- Transgenic Mouse Model Using Targeted Microbubbles. Nanomaterials (Basel). 2022 Jan 17;12(2):280. doi: 10.3390/nano12020280. PMID: 35055297; PMCID: PMC8779209.

Lee CK, Atibalentja DF, Yao LE, Park J, Kuruvilla S, Felsher DW. Anti-PD-L1 F(ab) Conjugated PEG-PLGA Nanoparticle Enhances Immune Checkpoint Therapy. Nanotheranostics. 2022 Jan 16;6(3):243-255. doi: 10.7150/ntno.65544. PMID: 35145835; PMCID: PMC8824669.

Theruvath J, Menard M, Smith BAH, Linde MH, Coles GL, Dalton GN, Wu W, Kiru L, Delaidelli A, Sotillo E, Silberstein JL, Geraghty AC, Banuelos A, Radosevich MT, Dhingra S, Heitzeneder S, Tousley A, Lattin J, Xu P, Huang J, Nasholm N, He A, Kuo TC, Sangalang ERB, Pons J, Barkal A, Brewer RE, Marjon KD, Vilches-Moure JG, Marshall PL, Fernandes R, Monje M, Cochran JR, Sorensen PH, Daldrup-Link HE, Weissman IL, Sage J, Majeti R, Bertozzi CR, Weiss WA, Mackall CL, Majzner RG. Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication. Nat Med. 2022 Jan 13. doi: 10.1038/s41591-021-01625-x. Epub ahead of print. PMID: 35027753.

Duan H, Baratto L, Hatami N, Liang T, Mari Aparici C, Davidzon GA, Iagaru A. 68Ga-PSMA11 PET/CT for biochemically recurrent prostate cancer: Influence of dual-time and PMT- vs SiPM-based detectors. Transl Oncol. 2022 Jan;15(1):101293. doi: 10.1016/j.tranon.2021.101293. Epub 2021 Nov 22. PMID: 34823095; PMCID: PMC8626686.

Wang H, Hu Z, Sukumar UK, Bose RJ, Telichko A, Dahl JJ, Paulmurugan R. Ultrasound-Guided Microbubble-Mediated Locoregional Delivery of Multiple MicroRNAs Improves Chemotherapy in Hepatocellular Carcinoma. Nanotheranostics. 2022 Jan 1;6(1):62-78. doi: 10.7150/ntno.63320. PMID: 34976581; PMCID: PMC8671967.