Education:

PhD, Osaka University School of Medicine, 2006
MS, Osaka University School of Medicine, 2003
BS, Gunma University School of Medicine, 2000

Contact Information:

Research Interests:

Cancer stem cell, Molecular imaging, signal transduction, Drug discovery, Translational research

Recent Publications:

1. Tatsumi N, Oji Y, Tsuji N, Tsuda A, Higashio M, Aoyagi S, Fukuda I, Ito K, Nakamura J, Takashima S, Kitamura Y, Miyai S, Jomgeow T, Li Z, Shirakata T, Nishida S, Tsuboi A, Oka Y, Sugiyama H. Wilms' tumor gene WT1-shRNA as a potent apoptosis-inducing agent for solid tumors. Int J Oncol.. 2008; Mar;32(3):701-11.():.
2. Fujiki F, Oka Y, Tsuboi A, Kawakami M, Kawakatsu M, Nakajima H, Elisseeva OA, Harada Y, Ito K, Li Z, Tatsumi N, Sakaguchi N, Fujioka T, Masuda T, Yasukawa M, Udaka K, Kawase I, Oji Y, Sugiyama H. Identification and characterization of a WT1 (Wilms Tumor Gene) protein-derived HLA-DRB1*0405-restricted 16-mer helper peptide that promotes the induction and activation of WT1-specific cytotoxic T lymphocytes. J Immunother. . 2007;Apr;30(3):282-93.
3. Ito K, Oji Y, Tatsumi N, Shimizu S, Kanai Y, Nakazawa T, Asada M, Jomgeow T, Aoyagi S, Nakano Y, Tamaki H, Sakaguchi N, Shirakata T, Nishida S, Kawakami M, Tsuboi A, Oka Y, Tsujimoto Y, Sugiyama H. Antiapoptotic function of 17AA(+)WT1 (Wilms' tumor gene) isoforms on the intrinsic apoptosis pathway. . Oncogene. . 2006;Jul 13;25(30):4217-29.
4. Jomgeow T, Oji Y, Tsuji N, Ikeda Y, Ito K, Tsuda A, Nakazawa T, Tatsumi N, Sakaguchi N, Takashima S, Shirakata T, Nishida S, Hosen N, Kawakami M, Tsuboi A, Oka Y, Itoh K, Sugiyama H. Wilms' tumor gene WT1 17AA(-)/KTS(-) isoform induces morphological changes and promotes cell migration and invasion in vitro. . Cancer Sci. . 2006;Apr;97(4):259-70.
5. Oji Y, Miyoshi S, Takahashi E, Koga S, Nakano Y, Shintani Y, Hirabayashi H, Matsumura A, Iuchi K, Ito K, Kishimoto Y, Tsuboi A, Ikegame K, Hosen N, Oka Y, Ogawa H, Maeda H, Hayashi S, Kawase I, Sugiyama H. Absence of mutations in the Wilms' tumor gene wt1 in de novo non-small cell lung cancers. Neoplasma.. 2004;51(1):17-20.
6. Oji Y, Suzuki T, Nakano Y, Maruno M, Nakatsuka S, Jomgeow T, Abeno S, Tatsumi N, Yokota A, Aoyagi S, Nakazawa T, Ito K, Kanato K, Shirakata T, Nishida S, Hosen N, Kawakami M, Tsuboi A, Oka Y, Aozasa K, Yoshimine T, Sugiyama H. . Overexpression of the Wilms' tumor gene W T1 in primary astrocytic tumors. Cancer Sci. . 2004;Oct;95(10):822-7.
7. Oji Y, Yano M, Nakano Y, Abeno S, Nakatsuka S, Ikeba A, Yasuda T, Fujiwara Y, Takiguchi S, Yamamoto H, Fujita S, Kanato K, Ito K, Jomgeow T, Kawakami M, Tsuboi A, Shirakata T, Nishida S, Hosen N, Oka Y, Aozasa K, Monden M, Sugiyama H. Overexpression of the Wilms' tumor gene WT1 in esophageal cancer. Anticancer Res.. 2004; Sep-Oct;24(5B):3103-8.