2016 BioEngineering 224

Winter 2016 BioEngineering 224/Radiology 222B

Instructors

Senior Research Scientist-Basic Life, Rad/Molecular Imaging Program at Stanford

israt@stanford.edu

Professor of Pathology and of Microbiology and Immunology and, by courtesy, of Chemical and Systems Biology

mbogyo@stanford.edu

Assistant Professor of Medicine (Cardiovascular) and of Radiology (Veterans Affairs)

Professor of Pediatrics (Neonatology), Emeritus

ccontag@stanford.edu

Associate Professor of Structural Biology and, by courtesy, of Electrical Engineering

adlz@stanford.edu

Associate Professor of Radiation Oncology (Radiation Physics) and, by courtesy, of Radiology (Molecular Imaging Program at Stanford)

(650) 723-5591

egraves@stanford.edu

Senior Research Scientist, Rad/Canary Center at Stanford for Cancer Early Detection

shori@stanford.edu

Assistant Professor of Radiology (Molecular Imaging Program at Stanford) and of Neurology (Neurology Research Faculty) Instructor, Radiology- Molecular Imaging Program at Stanford

Assistant Professor of Medicine (Oncology)

(650) 497-8370

Assistant Professor of Medicine (Oncology)

(650) 497-8370

Professor of Radiology (Radiological Sciences Lab)

This profile is not available

Course Logistics

Classes:	Mondays and Fridays 8:30-10:20 AM HRP T138B "Redwood Building" (between LabSurge and MSOB)
Reference Materials:	At Lane Library Molecular Imaging: Principles and Practice Weissleder R, Ross BD, Rehemtulla A, Gambhir SS 2010 People's Medical Publishing House Buy online Torigian DA, Zaidi H, Kwee TC, Saboury B, Udupa JK, Cho ZH, Alavi A.PET/MR imaging: technical aspects and potential clinical applications.Radiology. 2013;267(1):26-44. Kircher MF, Willmann JK. Molecular body imaging: MR imaging, CT, and US. part I. principles. Radiology. 2012;263(3):633-43. Kircher MF, Willmann JK. Molecular body imaging: MR imaging, CT, and US. Part II. Applications. Radiology. 2012;264(2):349-68.
Exams:	NO exams; Final presentations during our allocated Final Exam time March 16, 2016 from 8:30am-12:30pm HRP T138B Download Presentation Guidelines (PDF)
Grading:	Class participation (20%) Final presentation (80%)

/content/dam/sm/mips/documents/courses/bioe224/2016/

Course Syllabus

Week	Monday	Instructor	Friday	Instructor
1	1/4	Overview and Reporter Proteins: the Earth, Wind, and Sky C. Contag Lecture notes	1/8	Proteases as Targets for Optical Molecular Imaging M. Bogyo Lecture notes
2	1/11	Ultrasound Agents K. Wilson Lecture notes Kaneko OF. Ultrasound for molecular imaging and therapy in cancer. Quant Imaging Med Surg. 2012;2(2). Wilson KE. Acoustic and photoacoustic molecular imaging of cancer. JNM. 2013 Nov;54(11). Klibanov AL. Ultrasound molecular imaging with targeted microbubble contrast agents. J Nucl Cardiol. 2007;14(6).	1/15	Nanoparticle Imaging (Part I): Motivation, Chemistry, and Caveats J. Campbell Lecture notes Kiessling F.Nanoparticles for Imaging: Top or Flop? Radiology. 2014 Oct;273(1):10-28.
3	1/18	School holiday: no class	1/22	OCT, PAT A. de la Zerda
4	1/25	Nanoparticle Imaging (Part II): Applications of Optical and Nuclear Nanoparticles C. Zavaleta Lecture notes Bertrand N. Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology. Adv Drug Deliv Rev. 2014;66:2-25. In GK. Emerging chemotherapy agents in lung cancer: nanoparticle therapeutics for non-small cell lung cancer.Transl Cancer Res 2015;4(4):340-355. Mudshinge SR.Nanoparticles: Emerging carriers for drug delivery. Saudi Pharm J. 2011 Jul;19(3):129-41. Salata O. Applications of nanoparticles in biology and medicine. J Nanobiotechnology. 2004 Apr 30;2(1):3. Yu MK. Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy. Theranostics. 2012;2(1):3-44.	1/29	Contrast and Contrast Agents in X-Ray Imaging E. Graves Lecture notes Graves EE. X-ray Computed Tomography Principles and Contrast Agents. from Molecular Imaging Probes for Cancer Research, World Scientific Publishing Company, 2012.
5	2/1	Mathematical Modeling of Biomarkers in Cancer S. Hori Lecture notes Hori S. Mathematical Model Identifies Blood Biomarker–Based Early Cancer Detection Strategies and Limitations. Sci Transl Med. 2011 Nov 16;3(109):109ra116. Altrock PM. The mathematics of cancer: integrating quantitative models.Nat Rev Cancer. 2015 Dec;15(12):730-45.	2/5	Combining Molecular imaging with Circulating Biomarkers D. Kurtz Lecture notes Hanash SM.Emerging molecular biomarkers--blood-based strategies to detect and monitor cancer. Nat Rev Clin Oncol. 2011 Mar;8(3):142-50. Schwarzenbach H.Cell-free nucleic acids as biomarkers in cancer patients. Nat Rev Cancer. 2011 Jun;11(6):426-37.
6	2/8	PET/SPECT Radiochemistry (Part I) F. Chin	2/12	PET/SPECT Radiochemistry (Part II) F. Chin
7	2/15	School holiday: no class	2/19	Design & Development of Novel PET Agents - from bench to bedside M. James Lecture notes
8	2/22	Modern Molecular Imaging Strategies in the Clinic E. Mittra Lecture notes	2/26	Preclinical and Clinical Brain PET M. James Lecture notes
9	2/29	Molecular Imaging Strategies for Cardiac I. Chen Lecture notes	3/4	The Promise of ImmunoPET I. Alam Lecture notes
10	3/7	MRI Probes and Particles M. Moseley Lecture notes	3/11	MRI Probes or how to give an oral presentation M. Moseley Lecture notes
3/18	Final Presentations "A New and Novel Molecular Imaging Approach" During our allocated Final Exam time Wednesday, March 16th from 8:30am-12:30pm HRP-T138B Presentation Guidelines

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Winter 2016 BioEngineering 224/Radiology 222B

Instructors

Course Logistics

Course Syllabus

Overview and Reporter Proteins: the Earth, Wind, and Sky

Proteases as Targets for Optical Molecular Imaging

Ultrasound Agents

Nanoparticle Imaging (Part I): Motivation, Chemistry, and Caveats

School holiday: no class

OCT, PAT

Nanoparticle Imaging (Part II): Applications of Optical and Nuclear Nanoparticles

Contrast and Contrast Agents in X-Ray Imaging

Mathematical Modeling of Biomarkers in Cancer

Combining Molecular imaging with Circulating Biomarkers

PET/SPECT Radiochemistry (Part I)

PET/SPECT Radiochemistry (Part II)

School holiday: no class

Design & Development of Novel PET Agents - from bench to bedside

Modern Molecular Imaging Strategies in the Clinic

Preclinical and Clinical Brain PET

Molecular Imaging Strategies for Cardiac

The Promise of ImmunoPET

MRI Probes and Particles

MRI Probes or how to give an oral presentation